Azul de metileno: revisado |
Methylene blue: Revisited Ginimuge PR, Jyothi SD. J Anaesth Clin Pharmacol 2010;26:517-20 Methylene blue, an inhibitor of nitric oxide synthase and guanylate cyclase has many uses in medicine. It has been found to improve the hypotension associated with various clinical states. It also improves hypoxia and hyper dynamic circulation in cirrhosis of liver and severe hepatopulmonary syndrome. It also results in transient and reproducible improvement in blood pressure and cardiac function in septic shock
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Azul demetileno: utilidad en el tratamiento de la hipotensión arterialrefractaria en prematuros |
López-Suárez O, Pérez-Muñuzuri A, Baña-Souto A, Crespo-Suárez P, Couce-Pico ML, Fernández-Lorenzo JR
An Pediatr (Barc). 2011 Feb 5. [Epub ahead of print]
La hipotensión arterial del shock séptico se produce en parte como consecuencia de la liberación de mediadores inflamatorios. En este contexto, el exceso de óxido nítrico (NO)desempeña un papel en el desarrollo de dicha hipotensión, tal y como demuestran distintos trabajos que revelan niveles altos de nitratos, nitritos y metaboli tos del NO en recién nacidos con sepsis. Por este motivo, los inhibidores de la enzima NO sintasa se han ensayado con resultados variables, en el tratamiento del shock séptico.
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| Envenenamiento con indoxacarb: una presentación rara de metahemoglobinemia |
Indoxacarb poisoning: A rare presentation as methemoglobinaemia.
Chhabra R, Singh I, Tandon M, Babu R.
Department of Anaesthesiology and Intensive Care, Jaipur Golden Hospital, New Delhi, India.
Indian J Anaesth. 2010 May;54(3):239-41
Abstract
Indoxacarb is a broad-spectrum non-organophosphorus oxidiazine insecticide widely used in farming. Once absorbed it acts on sodium channels and blocks the flow of sodium ions. We report a case of indoxacarb poisoning in a farmer following suicidal consumption, manifested as unconsciousness, cyanosis and stationary SpO(2) values. Methemoglobinaemia was suspected on clinical presentation which was successfully managed with inj. methylene blue and other symptomatic and supportive treatment.
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| Experiencia anestesiológica con metahemoglobinemia detectada durante anestesia general para gastrectomía en cáncer avanzado. Informe de caso |
Anesthetic experience of methemoglobinemia detected during general anesthesia for gastrectomy of advanced gastric cancer -A case report-.
Cho SS, Park YD, Noh JH, Kang KO, Jun HJ, Yoon JS.
Department of Anesthesiology, Seoul Veterans Hospital, Seoul, Korea.
Korean J Anesthesiol. 2010 Nov;59(5):340-3. Epub 2010 Nov 25.
Abstract
Methemoglobinemia is an uncommon but potentially fatal disorder. Most cases have no adverse clinical consequence and require no treatment, but methemoglobinemia is often overlooked as a cause of low oxygen saturation, and often mistaken for the more common causes of hypoxia by anesthesiologists despite simple bedside tests that indicate the presence of this treatable abnormality. We present a 68-year-old female patient who underwent gastrectomy for advanced gastric cancer with bleeding. In the preoperative period, the patient showed cyanosis and oxygen saturation was 85% by pulse oximeter, but oxygen saturation by arterial blood gas analysis was 100%. After tracheal intubation, the methemoglobin level was 18.3%. Ascorbic acid and methylene blue were administered. During preanesthetic evaluation, the patient had not informed the anesthesiologist that she had been taking dapsone En este enlace puede bajar el PDF
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