Balance de líquidos en el niño grave / Children, critical care and fluid balance

Pueblo Mágico. Información / Information Sobrecarga de líquidos en niños críticamente enfermos. Fluid Overload in Critically Ill Children. Raina R1,2, Sethi SK3, Wadhwani N3, Vemuganti M4, Krishnappa V2,5, Bansal SB3. Front Pediatr. 2018 Oct 29;6:306. doi: 10.3389/fped.2018.00306. eCollection 2018. Abstract Background: A common practice in the management of critically ill patients is fluid resuscitation. An excessive administration of fluids can lead to an imbalance in fluid homeostasis and cause fluid overload (FO). In pediatric critical care patients, FO can lead to a multitude of adverse effects and increased risk of morbidity. Objectives: To review the literature highlighting impact of FO on a multitude of outcomes in critically-ill children, causative vs. associative relationship of FO with critical illness and current pediatric fluid management guidelines. Data Sources: A literature search was conducted using PubMed/Medline and Embase databases from the earliest available date until June 2017. Data Extraction: Two authors independently reviewed the titles and abstracts of all articles which were assessed for inclusion. The manuscripts of studies deemed relevant to the objectives of this review were then retrieved and associated reference lists hand-searched. Data Synthesis: Articles were segregated into various categories namely pathophysiology and sequelae of fluid overload, assessment techniques, epidemiology and fluid management. Each author reviewed the selected articles in categories assigned to them. All authors participated in the final review process. Conclusions: Recent evidence has purported a relationship between mortality and FO, which can be validated by prospective RCTs (randomized controlled trials). The current literature demonstrates that "clinically significant" degree of FO could be below 10%. The lack of a standardized method to assess FB (fluid balance) and a universal definition of FO are issues that need to be addressed. To date, the impact of early goal directed therapy and utility of hemodynamic parameters in predicting fluid responsiveness remains underexplored in pediatric resuscitation. KEYWORDS: acute kidney injury; critical care; fluid overload; intensive care; pediatric nephrology PDF Síndrome de dificultad respiratoria aguda pediátrica: manejo de líquidos en la UCIP. Pediatric Acute Respiratory Distress Syndrome: Fluid Management in the PICU. Ingelse SA1, Wösten-van Asperen RM1, Lemson J2, Daams JG3, Bem RA1, van Woensel JB1. Front Pediatr. 2016 Mar 21;4:21. doi: 10.3389/fped.2016.00021. eCollection 2016. Abstract The administration of an appropriate volume of intravenous fluids, while avoiding fluid overload, is a major challenge in the pediatric intensive care unit. Despite our efforts, fluid overload is a very common clinical observation in critically ill children, in particular in those with pediatric acute respiratory distress syndrome (PARDS). Patients with ARDS have widespread damage of the alveolar-capillary barrier, potentially making them vulnerable to fluid overload with the development of pulmonary edema leading to prolonged course of disease. Indeed, studies in adults with ARDS have shown that an increased cumulative fluid balance is associated with adverse outcome. However, age-related differences in the development and consequences of fluid overload in ARDS may exist due to disparities in immunologic response and body water distribution. This systematic review summarizes the current literature on fluid imbalance and management in PARDS, with special emphasis on potential differences with adult patients. It discusses the adverse effects associated with fluid overload and the corresponding possible pathophysiological mechanisms of its development. Our intent is to provide an incentive to develop age-specific fluid management protocols to improve PARDS outcomes. KEYWORDS: PARDS; children; critical care; fluid balance; lung edema; management PDF International Symposium on Ultrasound, ISURA May 9-1. Porto, Portugal Información / Information Congresos Médicos por Especialidades en todo Mundo Medical Congresses by Specialties around the World Información / Information Safe Anaesthesia Worldwide Delivering safe anaesthesia to the world's poorest people Informes / Information

Anestesiología y Medicina del Dolor 52 664 6848905 vwhizar@anestesia-dolor.org anestesia-dolor.org

Una célula madre recién descubierta que mantiene los huesos en crecimiento.

http://ortopediaytraumatologia.sytes.net/index.php/2019/03/04/una-celula-madre-recien-descubierta-que-mantiene-los-huesos-en-crecimiento/

https://www.nature.com/articles/d41586-019-00527-w?error=cookies_not_supported&code=76b9093a-8520-4e4c-95b1-e79b6aa59a67

doi: 10.1038/d41586-019-00527-w

© 2019 Springer Nature Publishing AG

Líquidos iv en perioperatorio / IV fluids in surgery

Marzo 4,  2019.  No. 3357

Ritual Chamula Convocatoria para Capítulos sobre Anestésicos Locales Call for Book Chapters on Local Anesthetics Información / Information Conceptos actuales de manejo de fluidos en vías de recuperación mejoradas. Current concepts of fluid management in enhanced recovery pathways. Makaryus R1, Miller TE2, Gan TJ3. Br J Anaesth. 2018 Feb;120(2):376-383. doi: 10.1016/j.bja.2017.10.011. Epub 2017 Nov 24. Abstract Perioperative fluid management impacts outcomes and plays a pivotal role in enhanced recovery pathways (ERPs). There have been major advances in understanding the effects of fluid therapy and administration during the perioperative period. Improving fluid management during this period leads to a decrease in complications, decrease in length of stay (LOS), and enhanced patient outcomes. It is important to consider preoperative and postoperative fluid management to be just as critical as intraoperative management given multiple associated benefits to the patients. Preoperative hydration with (complex) carbohydrate drinks up until 2 h before surgery is safe and should be encouraged, as this helps improve metabolism, decrease insulin resistance, reduce anxiety, and reduce nausea and vomiting. During the intraoperative period, the goals of fluid management are to maintain euvolemia using an individualized plan for fluid and haemodynamic management, matching the needs for monitoring with patient and surgical risk through goal-directed therapy (GDT). By combining the use of fluids and inotropes, GDT uses measurements and indicators of cardiac output and stroke volume to improve blood flow intraoperatively, and ultimately reduce LOS and complications. In the postoperative period, an early transition to oral hydration helps to enhance the conditions for healing and recovery from surgery. I.V. fluid therapy should be kept at a minimum, and urine output should not be the driving force for fluid administration. The optimization of perioperative fluid management is critical to ERPs as it helps improve pulmonary function, tissue oxygenation, gastrointestinal motility, and wound healing. KEYWORDS: fluid therapy; perioperative care; perioperative period PDF Terapia de fluidos en el contexto perioperatorio: una revisión clínica. Fluid therapy in the perioperative setting-a clinical review. Voldby AW1, Brandstrup B1. J Intensive Care. 2016 Apr 16;4:27. doi: 10.1186/s40560-016-0154-3. eCollection 2016. Abstract BACKGROUND: Perioperative hypovolemia and fluid overload have effects on both complications following surgery and on patient survival. Therefore, the administration of intravenous fluids before, during, and after surgery at the right time and in the right amounts is of great importance. This review aims to analyze the literature concerning perioperative fluid therapy in abdominal surgery and to provide evidence-based recommendations for clinical practice. RESULTS: Preoperative oral or intravenous administration of carbohydrate containing fluids has been shown to improve postoperative well-being and muscular strength and to reduce insulin resistance. Hence, the intake of fluid (preferably containing carbohydrates) should be encouraged up to 2 h prior to surgery in order to avoid dehydration. Excessive intravenous fluid administration adds to tissue inflammation and edema formation, thereby compromising tissue healing. During major abdominal surgery a "zero-balance" intraoperative fluid strategy aims at avoiding fluid overload (and comparable to the so-called restrictive approach) as well as goal-directed fluid therapy (GDT). Both proved to significantly reduce postoperative complications when compared to "standard fluid therapy". Trials comparing "restrictive" or zero-balance and GDT have shown equal results, as long as fluid overload is avoided in the GDT group as well (categorized as "zero-balance GDT"). It is possible that high-risk surgical patients, such as those undergoing acute surgery, may benefit from the continuous monitoring of circulatory status that the GDT provides. Data on this group of patients is not available at present, but trials are ongoing. CONCLUSION: In elective surgery, the zero-balance approach has shown to reduce postoperative complications and is easily applied for most patients. It is less expensive and simpler than the zero-balance GDT approach and therefore recommended in this review. In outpatient surgery, 1-2 L of balanced crystalloids reduces postoperative nausea and vomiting and improves well-being. KEYWORDS: Fluid therapy; Goal-directed fluid therapy; Outcome of surgery; Postoperative complications; Restricted; Third space; Third space loss PDF La administración perioperatoria de líquido intravenoso cristaloide tamponado versus no tamponado para mejorar los resultados después de procedimientos quirúrgicos en adultos: una revisión sistemática Cochrane Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures: a Cochrane systematic review. Odor PM1, Bampoe S2, Dushianthan A3, Bennett-Guerrero E4, Cro S5, Gan TJ4, Grocott MPW6, James MFM7, Mythen MG1, O'Malley CMN8, Roche AM9, Rowan K10, Burdett E11. Perioper Med (Lond). 2018 Dec 13;7:27. doi: 10.1186/s13741-018-0108-5. eCollection 2018. Abstract BACKGROUND: Buffered intravenous fluid preparations contain substrates to maintain acid-base status. The objective of this systematic review was to compare the effects of buffered and non-buffered fluids administered during the perioperative period on clinical and biochemical outcomes. METHODS: We searched MEDLINE, EMBASE, CINAHL and the Cochrane Library until May 2017 and included all randomised controlled trials that evaluated buffered versus non-buffered fluids, whether crystalloid or colloid, administered to surgical patients. We assessed the selected studies for risk of bias and graded the level of evidence in accordance with Cochrane recommendations. ....CONCLUSIONS: Small effect sizes for biochemical outcomes and lack of correlated clinical follow-up data mean that robust conclusions on major morbidity and mortality associated with buffered versus non-buffered perioperative fluid choices are still lacking. Buffered fluid may have biochemical benefits, including a significant reduction in postoperative hyperchloraemia and metabolic acidosis. KEYWORDS: Fluid therapy; Plasma substitutes; Surgery PDF Congresos Médicos por Especialidades en todo Mundo Medical Congresses by Specialties around the World Información / Information Safe Anaesthesia Worldwide Delivering safe anaesthesia to the world's poorest people Informes / Information

Anestesiología y Medicina del Dolor 52 664 6848905 vwhizar@anestesia-dolor.org anestesia-dolor.org