Clinical Care Guidelines
Guidelines regarding thrombosis and thrombophilia
A. DVT and PE Prevention and Treatment - General Guidelines:
1. ACCP 2008
ACCP Guidelines for Antithrombotic and Thrombolytic Therapy: 8th Edition
Evidence-based treatment recommendations are provided for prevention and treatment of arterial and venous thromboembolism, including in pregnant women and children, by a group of experts from the American College of Chest Physicians (ACCP), .. ACCP Guidelines for Antithrombotic and Thrombolytic Therapy: 8th Edition; Chest 2008 Jun;133(6 Suppl):110S-112S.
2. AHA 2011 DVT and PE
Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis and chronic thromboembolic pulmonary hypertension. A scientific statement from the American Heart Association
Evidence-based management recommendations for iliofemoral DVT, massive and submassive PE, chronic thromboembolic pulmonary hypertension and postthrombotic syndrome are addressed in this statement by a group of experts brought together by the American Heart Association (AHA). Jaff MR, McMurtry MS, Archer SL, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis and chronic thromboembolic pulmonary hypertension. A scientific statement from the American Heart Association. Circulation 2011,123(pre-published on the web).
3. AAOS 2011
Clinical Guideline on Prevention of Pulmonary Embolism in Patients Undergoing Total Hip or Knee Arthroplasty
Recommendations from the American Academy of Orthopedic Surgeons (AAOS) on DVT prophyalxis after orthopedic procedures. Am Academy Ortho Surg (AAOS) Clinical Guideline; Aug 2011
4. ACP 2011
Clinical Guidelines:Venous Thromboembolism Prophylaxis in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians
Recommendations from the American College of Physicians regarding prophylaxis in hospitalized patients. Amir Qaseem, Roger Chou, Linda L. Humphrey, Melissa Starkey, and Paul Shekelle for the Clinical Guidelines Committee of the American College of Physicians Ann Intern Med November 1, 2011 155:625-632
5. ASH 2011
Clinical Practice Guide on Anticoagulant Dosing and Management of Anticoagulant-Associated Bleeding Complications in Adults
The American Society of Hematology has developed a pocket-sized Quick Reference guide adapted in part from The American College of Chest Physicians Evidence-Based Clinical Practice Guideline on Antithrombotic and Thrombolytic Therapy (8th Edition).
The American Society of Hematology has developed a pocket-sized Quick Reference guide adapted in part from The American College of Chest Physicians Evidence-Based Clinical Practice Guideline on Antithrombotic and Thrombolytic Therapy (8th Edition).
B. Pregnancy, VTE and thrombophilia guidelines
1. ACOG 2011
Guidelines from the American College of Obstetricians and Gynecologists regarding the prevention, management and treatment of blood clots during pregnancy. Obstetrics & Gynecology. 118(3):718-729, September 2011. Note: journal license required to view full article
Review of common thrombophilias and their association with maternal venous thromboembolism risk, adverse pregnancy outcomes, indications for screening to detect these conditions and management options during pregnancy. Obstetrics & Gynecology. 118(3):730-740, September 2011. Note: journal license required to view full article.
C. Cerebral Venous Thrombosis Guidelines:
1. AHA 2011 Cerebral venous thrombosis
Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Health Care Professionals from the American Heart Association
This consensus statement provides a comprehensive overview of cerebral venous sinus thrombosis and provides evidence-based recommendations for its diagnosis, management, and treatment. The group of experts was brought together by the American Heart Association (AHA). Gustavo Saposnik et al. Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Healthcare Professionals; Stroke. 2011 Apr;42(4):1158-1192. Epub 2011 Feb 3.
D. Cancer and VTE guidelines:
1. NCCN 2010
NCCN Clinical Practice Guidelines for Venous Thromboembolic Disease
Comprehensive. Evidence-based guidelines from the National Comprehensive Cancer Network (NCCN) covering prevention, care and management of venous thromboembolism (VTE) in cancer patients. Note: this site requires registration (free) before being able to view this document.
2. ACCP 2008 - Prevention of VTE in Cancer Patients
Prevention of Venous Thromboembolism
Discusses the prevention of venous thromboembolism (VTE), including cancer patients, and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Geerts WH et al. Prevention of Venous Thromboembolism; Chest. 2008;133:381S-453S
3. ACCP 2008 – Treatment of VTE in Cancer patients
Antithrombotic Therapy for Venous Thromboembolic Disease
Discusses the treatment of venous thromboembolism (VTE), including cancer patients, and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Kearon C et al. Antithrombotic Therapy for Venous Thromboembolic Disease; Chest. 2008;133:454S-545S.
3. ASCO 2007
American Society of Clinical Oncology Guideline: Recommendations for Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer
Detailed, evidence-based recommendations for the use of anticoagulation in the prevention and treatment of venous thromboembolism (VTE) in patients with cancer. Lyman GH et al. American Society of Clinical Oncology Guideline: Recommendations for Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer. J Clin Oncol. 2007;25:5490-5505;
4. International Myeloma Working Group 2008
Myeloma Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma
Recommendations for VTE Prophylaxis in Multiple Myeloma by the International Myeloma Working Group.. Palumbo A et al. Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma.. Leukemia. 2008;22:414-423. Note: journal site license required to view full article.
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