viernes, 29 de julio de 2011

MODY review




MODY
History, genetics, pathophysiology, and clinical decision making





Studies conducted at the University
of Michigan for 60 years and at the
University of Chicago for approximately
25 years form the basis of this
review. As no field of study can develop
or progress in isolation, we have included
selected investigations performed in other
centers.
EARLY HISTORY—In the academic
year 1949–1950, one of us (S.S.F.), while
a first-year Fellow in Endocrinology and
Metabolism at the University of Michigan
(Jerome W. Conn, Division Chief), initiated
a prospective, long-term study on the
diagnosis, natural history, and clinical
genetics of diabetes. Starting with known
diabetic patients from the Diabetes Clinic,.......





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