| El uso de un sistema de puntuación para guiar la tromboprofilaxis en una población de embarazadas de alto riesgo |
The use of a scoring system to guide thromboprophylaxis in a high-risk pregnant population.
Schoenbeck D, Nicolle A, Newbegin K, Hanley J, Loughney AD.
Department of Women's Services and Royal Victoria Infirmary, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK.
Thrombosis.2011;2011:652796. Epub 2011 Sep 8.
Abstract
Guidelines for thromboprophylaxis in pregnancy are usually based upon clinical observations and expert opinion. For optimal impact, their use must be attended by consistency in the advice given to women. In this observational study, we evaluated the performance of a scoring system, used as a guide for clinicians administering dalteparin to pregnant women at increased risk of venous thromboembolism. The work included 47 women treated with dalteparin prior to adoption of the scoring system and 58 women treated with dalteparin after its adoption. The indication for thromboprophylaxis was recorded in each case together with details of the regimen employed, obstetric, and haematological outcomes. The main outcome measure was to determine whether consistency improved after adoption of the scoring system. We also recorded the occurrence of any new venous thromboembolism, haemorrhage, the use of regional anaesthesiaduring labour, evidence of allergy, and thrombocytopenia. We found that use of the scoring system improved the consistency of advice and increased the mean duration of thromboprophylaxis. None of the subjects suffered venous thromboembolism after assessment using the scoring system. There was no increase in obstetric or anaesthetic morbidity when dalteparin was given antenatally period and no evidence of heparin-induced thrombocytopenia.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200277/pdf/THROMB2011-652796.pdf
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