Prion - una visión general / Prion - An Overview

Marzo 10, 2017. No. 2624

Prion - una visión general Prion - An Overview Edited by Yusuf Tutar, ISBN 978-953-51-3002-4, Print ISBN 978-953-51-3001-7, 236 pages, Publisher: InTech, Chapters published March 08, 2017 under CC BY 3.0 license DOI: 10.5772/63289 Edited Volume Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded infectious protein agent forms the pathogenesis of the disease. This book presents pathology of the disease along with current knowledge of the structure-activity mechanism in the first two sections. Dyshomeostasis of metals is implicated in the pathogenesis of prions, and this influence is discussed further to understand the prion mechanism. Genetic resistance and immunobiology of the disease are elaborated in the following section. Finally, a computational study on the dynamics of the prion propagation provides a structural basis of the mechanism. Libro / Book Curso sobre Anestesia en Trasplantes, Cirugía abdominal, Plástica, Oftalmología y Otorrinolaringología. Committee for European Education in Anaesthesiology (CEEA)  y el Colegio de Anestesiólogos de León A.C. Abril 7-9, 2017, León Guanajuato, México Informes  (477) 716 06 16, kikinhedz@gmail.com Vacante para Anestesiología Pediátrica Hospital de Especialidades Pediátrico de León, Guanajuato  México  Informes con la Dra Angélica García Álvarez  angy.coachanestped@gmail.com o al teléfono 477 101 8700 Ext 1028

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