Dexmedetomidine in pulmonary hypertension: A Review Abhijit S. Nair, MD Consultant Anesthesiologist, Yashoda Hospital, Somajiguda, Rajbhavan Road , Hyderabad- 50005282. ABSTRACT Patients with pulmonary hypertension often have adverse outcomes after anesthesia. Tachycardia, hypertension, hypervolemia, increased intrathoracic pressure, acidosis, painful stimuli and hyperthermia are triggering factors for adverse perioperative events. Dexmedetomidine is a centrally acting α2agonist which, due to its desirable properties like sympatholysis, bradycardia and μ agonism, can be a useful agent for patients with pulmonary hypertension. Dexmedetomidine also has the ability to potentiate inhalational, intravenous and regional anesthetics when it is used as an adjunct. Key words: Pulmonary arterial hypertension; Dexmedetomidine; Anesthesia. Citation: Nair AS. Dexmedetomidine in pulmonary hypertension: A Review. Anaesth Pain & Intensive Care 2013;17(3):279-281
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