Dexmedetomidine and propofol for monitored anesthesia care in the middle ear surgery.
Verma R, Gupta R, Bhatia V K, Bogra J, Agarwal S P.
Indian J Otol [serial online] 2014 [cited 2014 May 3];20:70-4.
Abstract
Context: Local anaesthesia with sedation is a well established approach used for tympanoplasty. Dexmedetomidine is a new drug which acts on α2-adrenergic receptors in the dorsal horn of the spinal cord to produce analgesic effects. Aims: Efficacy and safety of intravenous dexmedetomidine in comparison to propofol. Setting and Design: Randomized controlled trial. Materials and Methods: Eighty patients were randomly allocated to receive either dexmedetomidine or propofol as intravenous bolus followed by the same in infusion supplemented with local anaesthesia for tympanoplasty. Statistical Analyses Used: Statistical Package for Social Sciences version 15.0. Results:Dexmedetomidine and propofol provides adequate sedation but the use of propofol is associated with more requirements of rescue analgesia and poor patient and surgeon satisfaction. Conclusion: These results suggest that dexmedetomidine provides adequate sedation with analgesia and good surgical and patient comfort without any adverse effects for patients undergoing tympanoplasty under local anaesthesia
Keywords: Dexmedetomidine, Propofol, Sedation, Surgery
http://www.indianjotol.org/downloadpdf.asp?issn=0971-7749;year=2014;volume=20;issue=2;spage=70;epage=74;aulast=Verma;type=2
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Anestesiología y Medicina del Dolor
www.anestesia-dolor.org |
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