Ketamina / Ketamine

Junio 27, 2016. No. 2370

Dosis subanestésicas de ketamina para analgesia perioperatoria Intravenous sub-anesthetic ketamine for perioperative analgesia. Gorlin AW1, Rosenfeld DM1, Ramakrishna H1. J Anaesthesiol Clin Pharmacol. 2016 Apr-Jun;32(2):160-7. doi: 10.4103/0970-9185.182085. Abstract Ketamine, an N-methyl-d-aspartate antagonist, blunts central pain sensitization at sub-anesthetic doses (0.3 mg/kg or less) and has been studied extensively as an adjunct for perioperative analgesia. At sub-anesthetic doses, ketamine has a minimal physiologic impact though it is associated with a low incidence of mild psychomimetic symptoms as well as nystagmus and double vision. Contraindications to its use do exist and due to ketamine's metabolism, caution should be exercised in patients with renal or hepatic dysfunction. Sub-anesthetic ketamine improves pain scores and reduces perioperative opioid consumption in a broad range of surgical procedures. In addition, there is evidence that ketaminemay be useful in patients with opioid tolerance and for preventing chronic postsurgical pain. PDF Aplicaciones prácticas de las propiedades neuroregenerativas de ketamina: experiencia en el mundo real Practical application of the neuroregenerative properties of ketamine: real world treatment experience. Henderson TA1. Neural Regen Res. 2016 Feb;11(2):195-200. doi: 10.4103/1673-5374.177708. Abstract While controversial, ketamine has emerged as an effective treatment for refractory depression. Serial infusions have been performed 3 times per week, but our practical experience has challenged this precept concerning infusion frequency. Depression is associated with neuron loss, reduced synapse numbers, and dearborization of dendrites. Ketamine appears to potently induce mechanisms which reverse these neurodegenerative processes. Ketamine not only blocks the glutamate receptor, it activates eukaroyotic elongation factor 2 (eEF2). This, in turn, activates brain-derived neurotrophic factor (BDNF) protein synthesis. This is thought to underlie ketamine's enduring benefits. In addition, ketamine alters glycogen synthase kinase-3 (GSK-3) phosphorylation, probably responsible for its rapid antidepressant effect. Notably, inhibition of the BDNF receptor does not block the immediate benefits of ketamine, but does prevent the enduring effects. Neuro-Luminance Ketamine Infusion Centers have been treating patients with serial ketamine infusions for over three years. Our methods differ from what is often reported, as we perform infusions only once per week and generally do not perform more than five infusions. Data from 100 patients showed that 80% of the patients responded. The baseline Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR) score was 17.8 ± 2.8. Responders to ketamineshowed a drop in QIDS-SR score of 10.8 ± 3.5, while non-responders showed a 0.8 ± 1.8 change. Moreover, they often had persistent benefits over several months. Recently, it was proposed that psychotomimetic effects are necessary during a ketamine infusion to yield effective antidepressant benefits. Yet, only one patient in our clinic has experienced hallucinations in three years. Nevertheless, 80% of our patients show clinical improvement. Further studies of clinical methods for ketamine infusion therapy are encouraged. KEYWORDS: Ketamine; brain-derived neurotrophic factor; depression; infusion therapy; safety PDF Comité Europeo de Enseñanza en Anestesiología Curso de Actualización en Anestesiología Anestesia por Especialidades y Simposio Anestesia y Cirugía Plástica Seguras Agosto 5-7, 2016. Tijuana BC, México Información Dr. Sergio Granados Tinajero granadosts@gmail.com  16th World Congress of Anaesthesiologists 28 August - 2 September 2016  Hong Kong Convention and Exhibition Centre World Federation of Societies of Anaesthesiologists http://wca2016.com/

Anestesiología y Medicina del Dolor 52 664 6848905 vwhizar@anestesia-dolor.org anestesia-dolor.org Copyright © 2015

Bibliotecas. Noticias

bibliotecas
Notificaciones diarias ⋅ 3 de julio de 2016
NOTICIAS


El Eco de Tandil
Se agrava la situación de las bibliotecas con casi siete meses de subsidios adeudados
El Eco de Tandil
Ante la grave situación que atraviesan las bibliotecas populares por la falta de pago de siete meses del subsidio que les otorga el Gobierno provincial ...




EnergyPress
Graves problemas de las bibliotecas populares de la provincia de Buenos Aires
EnergyPress
"La situación de las Bibliotecas Populares es grave", así lo manifiesta la Federación que nuclea a las bibliotecas populares en la provincia de Buenos ...




zonaretiro.com
Un total de 25 bibliotecas municipales ofrecen cursos y talleres infantiles relacionados con el ...
Europa Press
Un total de 25 bibliotecas municipales proporcionarán en el mes de julio actividades y talleres infantiles relacionadas con los libros, la cultura y el ...
25 bibliotecas municipales ofrecen cursos y talleres infantiles - Madridpress.com
Las bibliotecas de la capital ofrecen talleres para niños en el mes de julio - Madrid Actual
Cobertura total de la noticia




Almuñécar Digital
La Red de Bibliotecas Públicas Municipales organiza sus 'Talleres de Verano'
Almuñécar Digital
La edil de Educación ha señalado que gracias a la Red de Bibliotecas Municipales se puede atender a los usuarios y colaborar con las asociaciones ...




Unión de Morelos
Preparan ya “Mis vacaciones en la biblioteca” en Jojutla
Unión de Morelos
Foto/ Evaristo Torres Ocampo Niños de la región sur ya se pueden inscribir en el programa “Mis vacaciones en la biblioteca”, que comenzará el 18 de ...




La Crónica de Salamanca
4 conciertos de blues en la Torrente Ballester
La Crónica de Salamanca
El tradicional ciclo de cine al aire libre, talleres, exposiciones y conciertos de blues protagonizan la programación de las bibliotecas municipales para ...




Peninsular Digital
Habilitan módulos digitales
Peninsular Digital
Marlen Carballo Contreras, coordinadora Municipal de Bibliotecas explicó que es un servicio para niños y jóvenes que necesitan utilizar una ...




Primer Plano
Convocan a los Cursos de Verano 2016; Habrá Múltiples Actividades
Primer Plano
Eso y más se impartirán en los cursos de verano de las bibliotecas, ... regional de bibliotecas, Gregorio García Torres, en conferencia de prensa.


WEB

Bibliotecas Comprometidas con la Excelencia
Universidad de La Laguna
Los orígenes de este grupo de colaboración para el desarrollo de acciones de benchmarking se remontan al año 2008, cuando varias bibliotecas de ...



Investigadores del legado de Gabo podrán viajar a Austin
Biblioteca Nacional de Colombia
El Ministerio de Cultura y la Biblioteca Nacional de Colombia, en colaboración con la Universidad de Texas en Austin, invitan a los investigadores ...

Más de cuidasdos paliativos / More on palliative care

Junio 30, 2016. No. 2373

La Unidad de Cuidados Paliativos en un Centro Integral del Cáncer como Cruce de Camino Oncológico de los pacientes. The Palliative-Supportive Care Unit in a Comprehensive Cancer Center as Crossroad for Patients' Oncological Pathway. Mercadante S1, Adile C1, Caruselli A2, Ferrera P1, Costanzi A3, Marchetti P3, Casuccio A4. PLoS One. 2016 Jun 22;11(6):e0157300. doi: 10.1371/journal.pone.0157300. eCollection 2016. Abstract AIM: The aim of this study was to assess how an admission to an acute palliative-supportive care unit (APSCU), may influence the therapeutic trajectory of advanced cancer patients. METHODS: A consecutive sample of advanced cancer patients admitted to APCU was assessed. The following parameters were collected: patients demographics, including age, gender, primary diagnosis, marital status, and educational level, performance status and reasons for and kind of admission, data about care-givers, recent anticancer treatments, being on/off treatment or uncertain, the previous care setting, who proposed the admission to APSCU. Physical and psychological symptoms were evaluated at admission and at time of discharge. The use of opioids was also recorded. Hospital staying was also recorded. At time of discharge the parameters were recorded and a follow-up was performed one month after discharge. RESULTS: 314 consecutive patients admitted to the APSCU were surveyed. Pain was the most frequent reason for admission. Changes of ESAS were highly significant, as well as the use of opioids and breakthrough pain medications (p <0.0005). A significant decrease of the number of "on therapy" patients was reported, and concomitantly a significant number of "off-therapy" patients increased. At one month follow-up, 38.9% patients were at home, 19.7% patients were receiving palliative home care, and 1.6% patients were in hospice. 68.5% of patients were still living. CONCLUSION: Data of this study suggest that the APSCU may have a relevant role for managing the therapeutic trajectory of advanced cancer patients, limiting the risk of futile and aggressive treatment while providing an appropriate care setting. PDF Pacientes paliativos baja el cuidado del anestesiólogo Palliative patients under anaesthesiological care: a single-centre retrospective study on incidence, demographics and outcome. Lassen CL1, Aberle S2,3, Lindenberg N4, Bundscherer A5, Klier TW6, Graf BM7, Wiese CH8. BMC Anesthesiol. 2015 Nov 13;15:164. doi: 10.1186/s12871-015-0143-4. Abstract BACKGROUND: While anesthesiologist's involvement in palliative care has been widely researched, extensive data on palliative patients under anesthesiological care in the operating room is missing. This study was performed to assess the incidence, demographics, and outcome ofpalliative patients under anesthesiological care. CONCLUSIONS: Palliative patients are treated by anesthesiologists under varying circumstances. Anesthesiologists need to identify these patients and need to be aware of their characteristics to adequately attend to them during the periprocedural period. PDF Comité Europeo de Enseñanza en Anestesiología Curso de Actualización en Anestesiología Anestesia por Especialidades y Simposio Anestesia y Cirugía Plástica Seguras Agosto 5-7, 2016. Tijuana BC, México Información Dr. Sergio Granados Tinajero granadosts@gmail.com  16th World Congress of Anaesthesiologists 28 August - 2 September 2016  Hong Kong Convention and Exhibition Centre World Federation of Societies of Anaesthesiologists http://wca2016.com/

Anestesiología y Medicina del Dolor 52 664 6848905 vwhizar@anestesia-dolor.org anestesia-dolor.org Copyright © 2015