lunes, 28 de agosto de 2017

Neuronas adictivas / Addictive neurons.

Agosto 28, 2017. No. 2794






Neuronas adictivas
Addictive neurons.
Kodirov SA1,2,3,4,5.
Ther Targets Neurol Dis. 2017;4. pii: e1498. Epub 2017 Jan 30.
Abstract
Since the reward center is considered to be the area tegmentalis ventralis of the hypothalamus, logically its neurons could mainly be responsible for addiction. However, the literature asserts that almost any neurons of CNS can respond to one or another addictive compound. Obviously not only addictive nicotine, but also alcohol, amphetamine, cannabis, cocaine, heroin and morphine may influence dopaminergic cells alone in VTA. Moreover, paradoxically some of these drugs ameliorate symptoms, counterbalance syndromes, cure diseases and improve health, not only those related to the CNS and in adults, but also almost all other organs and in children, e.g. epilepsy.
KEYWORDS: ADP; AHP; LTD; LTP; amygdala; lateral septum; medial prefrontal cortex; paired pulse facilitation; rebound action potential; spike



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