Micropartículas circulantes en mujeres migrañosas con aura
Circulating endothelial microparticles in female migraineurs with aura.
Cephalalgia. 2015 Feb;35(2):88-94. doi: 10.1177/0333102414529671. Epub 2014 Apr 8.
Abstract
BACKGROUND AND PURPOSE: Endothelial microparticles (EMPs) are vesicles that are released from activated endothelial cells and serve as a surrogate for endothelial dysfunction (ED). ED may be involved in migraine pathophysiology and contribute to the increased risk of ischemic stroke, particularly in female migraineurs with aura (MA). We sought to determine whether EMPs are elevated in women with MA.
CONCLUSION: EMP levels are significantly elevated in women with MA and correlated with increased AI. Our findings suggest that endothelial activation is present in women with MA. This might contribute to higher stroke risk in MA.
KEYWORDS: Endothelial microparticle; endothelial dysfunction; migraine; stroke risk
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