Estimulación del nervio vago para epilepsia. Una revisión de los mecanismos periféricos
Vagus nerve stimulation for epilepsy: A review of the peripheral mechanisms.
Krahl SE.
Surg Neurol Int [serial online] 2012 [cited 2012 Dec 1];3:47-52.
Vagus nerve stimulation (VNS) is a unique epilepsy treatment in that a peripheral intervention is used to treat a disease that is entirely related to pathological events occurring within the brain. To understand how stimulation of the vagus nerve can be used to stop seizures, an understanding of the peripheral anatomy and physiology of the vagus nerve is essential. The peripheral aspects of the vagus nerve are discussed in this review, with an explanation of which fibers and branches are involved in producing these antiepileptic effects, along with speculation about the potential for improving the therapy.
Keywords: Epilepsy, vagus nerve stimulation, peripheral nerves
http://www.surgicalneurologyint.com/text.asp?2012/3/2/47/91610
Estimulación del nervio vago para epilepsia. Un revisión de los mecanismos centrales
Vagus nerve stimulation for epilepsy: A review of central mechanisms
Krahl SE, Clark KB.
Surg Neurol Int [serial online] 2012 [cited 2013 Jan 7];3:255-9.
In a previous paper, the anatomy and physiology of the vagus nerve was discussed in an attempt to explain which vagus nerve fibers and branches are affected by clinically relevant electrical stimulation. This companion paper presents some of vagus nerve stimulation's putative central nervous system mechanisms of action by summarizing known anatomical projections of vagal afferents and their effects on brain biogenic amine pathways and seizure expression.
Keywords: Locus coeruleus, norepinephrine, raphe nuclei, serotonin, vagus nerve stimulation, seizures
http://www.surgicalneurologyint.com/text.asp?2012/3/5/255/103015
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Vagus nerve stimulation for epilepsy: A review of the peripheral mechanisms.
Krahl SE.
Surg Neurol Int [serial online] 2012 [cited 2012 Dec 1];3:47-52.
Vagus nerve stimulation (VNS) is a unique epilepsy treatment in that a peripheral intervention is used to treat a disease that is entirely related to pathological events occurring within the brain. To understand how stimulation of the vagus nerve can be used to stop seizures, an understanding of the peripheral anatomy and physiology of the vagus nerve is essential. The peripheral aspects of the vagus nerve are discussed in this review, with an explanation of which fibers and branches are involved in producing these antiepileptic effects, along with speculation about the potential for improving the therapy.
Keywords: Epilepsy, vagus nerve stimulation, peripheral nerves
http://www.surgicalneurologyint.com/text.asp?2012/3/2/47/91610
Estimulación del nervio vago para epilepsia. Un revisión de los mecanismos centrales
Vagus nerve stimulation for epilepsy: A review of central mechanisms
Krahl SE, Clark KB.
Surg Neurol Int [serial online] 2012 [cited 2013 Jan 7];3:255-9.
In a previous paper, the anatomy and physiology of the vagus nerve was discussed in an attempt to explain which vagus nerve fibers and branches are affected by clinically relevant electrical stimulation. This companion paper presents some of vagus nerve stimulation's putative central nervous system mechanisms of action by summarizing known anatomical projections of vagal afferents and their effects on brain biogenic amine pathways and seizure expression.
Keywords: Locus coeruleus, norepinephrine, raphe nuclei, serotonin, vagus nerve stimulation, seizures
http://www.surgicalneurologyint.com/text.asp?2012/3/5/255/103015
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
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