Google+

domingo, 15 de mayo de 2011

El Victor Ravens Diario Domingo, May. 15, 2011


Contribuyente
Artículo
Fuente
Tema

evidpediatria
Objetivo: estimar la inmunidad a largo plazo inducida por la vacuna contra la hepatitis B (HB) y la posible necesidad de una dosis de recuerdo. Fuentes de datos: hasta diciembre de 2008 se revisaro...
 evidenciasenpe...

TIME
Mike Huckabee announced he would not take another shot at the White House on Saturday night, telling viewers tuning into his Fox News talk show that he had made “a spiritual decision” not to run. T...
 swampland.time...
Política

HuffingtonPost
Sarah Silverman popped into the Fox booth to chat with Joe Buck during the 4th inning of Saturday night's Red Sox vs. Yankees game, and it quickly got weird. Silverman asked whether or not the spor...
 huffingtonpost...
Cultura y Espectáculos

nytimesscience
THE late Amos Tversky, a Stanford psychologist and a founding father of behavioral economics, used to say, “My colleagues, they study artificial intelligence; me, I study natural stupidity.” ...
 nytimes.com

nytimeshealth
THE GIST Being socially rejected doesn’t just feel bad. It hurts. THE SOURCE “Social Rejection Shares Somatosensory Representations With Physical Pain,” by Ethan F. Kross, Marc G. Be...
 nytimes.com
Salud

nytimesscience
WASHINGTON — President Obama, facing voter anger over high gasoline prices and complaints from Republicans and business leaders that his policies are restricting the development of domestic energy ...
 nytimes.com
Medio ambiente

nytimeshealth
We all know by now — don’t we? — that many of the synthetic chemicals in our food, personal-­care and cleaning products, toys and household goods are harming not just the environment but ourselves....
 nytimes.com
Salud

NIOSH
April 2011 DHHS (NIOSH) Publication Number 2011-149 As the largest organ of the body, the skin performs multiple critical functions, such as serving as the primary barrier to the external environme...
 cdc.gov
Salud

ScienceChannel
"Raising the Dead" Premieres Saturday, April 16At Obscura Antiques and Oddities, shop regular Laura Flook stumbles upon a disturbing, mysterious tonic -- made with actual testicles. Meanwhile, when...
 science.discov...
Cultura y Espectáculos

nytimesscience
When you consider Jane Goodall’s happy British childhood, largely spent outdoors and filled with horses, dogs, chickens and pet turtles — earthworms tucked beneath her pillow at night — and her adu...
 nytimes.com
Cultura y Espectáculos

nytimeshealth
CLIFTON, N.J. IN 2009, Deborah Gianelli, 58, of Montclair, was told she had celiac disease, a disorder in which the immune system attacks the small intestine in response to gluten, a pr...
 nytimes.com

pzmyers
You're all going, right? They've just announced the next Global Atheist Convention for 13-15 April, in Melbourne, Australia, with Dawkins, Dennett, Harris, and Hitchens committing to attending. The...
 scienceblogs.com
Educación

fayerwayer
Un grupo de investigadores de la Luleå University of Technology de Suecia desarrolló una silla de ruedas eléctrica pensada específicamente para personas ciegas. La silla es controlada a través de u...
 fayerwayer.com
Tecnología

nytimeshealth
Remember melatonin? In the 1990s, this over-the-counter dietary supplement was all the rage among frequent fliers, promoted as the miracle cure for jet lag. Now it is back in vogue, this time as a ...
 nytimes.com

Harvard
The Harvard Alumni Association (HAA) announced that Arne Duncan ’86 has been elected by his classmates to be this year’s chief marshal for Commencement. Selected from the ranks of the 25th reunion ...
 news.harvard.edu
Educación

nytimes
ABU DHABI, United Arab Emirates — Late one night last November, a plane carrying dozens of Colombian men touched down in this glittering seaside capital. Whisked through customs by an Emirati intel...
 nytimes.com
Política

HarvardResearch
New findings suggest that HIV-infected patients may delay the onset of AIDS by starting drug therapy earlier while their immune systems are stronger. Researchers including Lauren Cain, a research f...
 hsph.harvard.edu
Salud

elmundosalud
Desde que en 1854 el profesor de canto Manuel García inventara el laringoscopio tras mirarse en el espejo de unos escaparates y darse cuenta de que podía combinar pequeños espejos para observar sus...
 elmundo.es
Salud

nytimes
ON a nondescript street in Long Island City, Queens, is a mysterious gold-painted door with a drawing of a colorful tent and a sign that reads “Circus Warehouse.” Inside is a cavernous space with a...
 nytimes.com
Cultura y Espectáculos

gfry
NEW YORK | Sat May 14, 2011 8:42pm EDT NEW YORK (Reuters) - IMF Managing Director Dominique Strauss-Kahn was taken into custody on Saturday at JFK airport in New York and was being questioned in re...
 reuters.com
Negocios
Publicado por Bibliomanazteca en 1:19 0 comentarios
Etiquetas: , ,

Neuralgia postherpética: Una visión general de su fisiopatología, presentación y manejo


Neuralgia postherpética: Una visión general de su fisiopatología, presentación y manejo.
Postherpetic Neuralgia: An Overview of the Pathophysiology, Presentation, and Management.
Gharibo C, Kim C.
Pain Med News, 2011;1-7.
Postherpetic neuralgia (PHN) presents itself as a frustrating and fascinating subject within the realm of neuropathic pain. With herpes zoster affecting roughly 3.4 per 1,000 people, and nearly .49 per 1,000 people developing PHN annually, the subject continues to be a prevalent dilemma in want of further study. Drs. Christopher Gharibo and Carolyn Kim explore the diagnosis, treatment and management of this complicated condition
http://www.painmedicinenews.com/download/PostNeuralgiaPMN0411_WM.pdf
 

Terapia analgésica en neuralgia postherpética: Revisión sistemática cuantitativa.
Analgesic Therapy in Postherpetic Neuralgia: A Quantitative Systematic Review
Hempenstall K, Nurmikko TJ, Johnson RW, A'Hern RP, Rice AS
PLoS Med 2005;2(7): e164. doi:10.1371/journal.pmed.002016
Background
Postherpetic neuralgia (PHN) is a complication of acute herpes zoster, which is emerging as a preferred clinical trial model for chronic neuropathic pain. Although there are published meta-analyses of analgesic therapy in PHN, and neuropathic pain in general, the evidence base has been substantially enhanced by the recent publication of several major trials. Therefore, we have conducted a systematic review and meta-analysis for both efficacy and adverse events of analgesic therapy for PHN. Methods and Findings. We systematically searched databases (MEDLINE 1966-2004, EMBASE 1988-2004, CINAHL 1982-2002, and PubMed [29 October 2004]) for trials of PHN. We also searched references of retrieved studies and review articles for further trials. We included trials that examined adult patients with PHN of greater duration than 3 mo, that were blinded, randomised, and had at least one measure of pain outcome. Dichotomous pain outcome data were extracted for 50% decrease in baseline pain using a hierarchy of pain/pain-relief measurement tools. Where available, dichotomous data were also collected for adverse events. Calculated estimates of efficacy included relative benefit and number needed to treat. Of 62 studies identified, 35 were randomised controlled trials. Of these, 31 were placebo controlled and suitable for meta-analysis, from which it was possible to extract dichotomous efficacy outcome data from 25. This meta-analysis revealed that there is evidence to support the use of the following orally administered therapies: tricyclic antidepressants, "strong" opioids, gabapentin, tramadol, and pregabalin. Topical therapies associated with efficacy were lidocaine 5% patch and capsaicin. Finally, a single study of spinal intrathecal administration of lidocaine and methyl prednisolone demonstrated efficacy, although this has yet to be replicated.
Data suggest that the following therapies are not associated with efficacy in PHN: certain NMDA receptor antagonists (e.g., oral memantine, oral dextromethorphan, intravenous ketamine), codeine, ibuprofen, lorazepam, certain 5HT1 receptor agonists, and acyclovir. Topical administration of benzydamine, diclofenac/diethyl ether, and vincristine (iontophoresis) are similarly not associated with efficacy, nor are intrathecal administration of lidocaine alone or epidural administration of lidocaine and methylprednisolone, intravenous therapy with lidocaine, subcutaneous injection of Cronassial, or acupuncture. However, many of the trials that demonstrated a lack of efficacy represented comparatively low numbers of patient episodes or were single-dose studies, so it may be appropriate to regard such interventions as "not yet adequately tested" rather than demonstrating "no evidence of efficacy." Topical aspirin/diethyl ether has not been adequately tested. Conclusion. The evidence base supports the oral use of tricyclic antidepressants, certain opioids, and gabapentinoids in PHN. Topical therapy with lidocaine patches and capsaicin is similarly supported. Intrathecal administration of methylprednisolone appears to be associated with high efficacy, but its safety requires further evaluation


Atentamente
Anestesiología y Medicina del Dolor
Publicado por Bibliomanazteca en 0:50 0 comentarios
Etiquetas:
Suscribirse a: Entradas (Atom)