El hialuronano oral alivia el dolor de rodilla: una revisión

http://www.columnayortopedia.com.mx/academia/el-hialuronano-oral-alivia-el-dolor-de-rodilla-una-revision/

Oral hyaluronan relieves knee pain: a review.

Fuente
Este artículo es originalmente publicado en:

https://www.ncbi.nlm.nih.gov/pubmed/?term=Oral+hyaluronan+relieves+knee+pain%3A+a+review

https://nutritionj.biomedcentral.com/articles/10.1186/s12937-016-0128-2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729158/

De:

Oe M1,Tashiro T2,Yoshida H3,Nishiyama H4,Masuda Y5,Maruyama K6,

Koikeda T7,Maruya R8,Fukui N9

.

Nutr J.

2016 Jan 27;15:11. doi: 10.1186/s12937-016-0128-2.

Todos los derechos reservados para:

Copyright

© Oe et al. 2016Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Abstract

Hyaluronan (HA) is a component that is particularly abundant in the synovial fluid. Randomized, double-blinded, placebo-controlled trials carried out between 2008 and 2015 have proven the effectiveness of HA for the treatment of symptoms associated with synovitis, and particularly, knee pain, relief of synovial effusion or inflammation, and improvement of muscular knee strength. The mechanism by which HA exerts its effects in the living body, specifically receptor binding in the intestinal epithelia, has gradually been clarified. This review examines the effects of HA upon knee pain as assessed in clinical trials, as well as the mechanism of these effects and the safety of HA.

Resumen

El hialuronano (HA) es un componente particularmente abundante en el líquido sinovial. Los ensayos aleatorizados, doble ciego y controlados con placebo realizados entre 2008 y 2015 han demostrado la eficacia de la HA para el tratamiento de los síntomas asociados a la sinovitis y, en particular, el dolor en la rodilla, el alivio del derrame sinovial o la inflamación y la mejora de la fuerza muscular de la rodilla . El mecanismo por el cual el HA ejerce sus efectos en el cuerpo vivo, específicamente la unión al receptor en el epitelio intestinal, ha sido aclarado gradualmente. Esta revisión examina los efectos de HA sobre el dolor de rodilla evaluado en ensayos clínicos, así como el mecanismo de estos efectos y la seguridad de HA.

PMID:   26818459   PMCID:  

PMC4729158

DOI:  

10.1186/s12937-016-0128-2

[Indexed for MEDLINE]

Free PMC Article

#hialuronano#líquido sinovial#dolor#rodilla