La anestesia espinal-general disminuye la respuesta neuroendócrina al estrés en colecistectomía laparoscópica
Spinal-general anaesthesia decreases neuroendocrine stress response in laparoscopic cholecystectomy.
Calvo-Soto P, Martínez-Contreras A, -Hernández BT, And FP, Vásquez C.
Department of Anaesthesia, General Family Medicine and Zone Hospital No. 1, Mexican Social Security Institute, Colima, Mexico.
J Int Med Res. 2012;40(2):657-65.
Abstract
OBJECTIVE: A randomized clinical study to compare the stress response to laparoscopic cholecystectomy during spinal-general anaesthesia and epidural- general anaesthesia. METHODS: Women undergoing elective laparoscopic chole cystectomy were assigned to receive either spinal anaesthesia (SA group; n = 12) or epidural anaesthesia (EA group; n = 12), in addition to general anaesthesia. Plasma concentrations of cortisol, adrenocorticotrophic hormone (ACTH), noradrenaline, adrenaline and total catecholamines were measured pre- and intraoperatively. RESULTS: Intraoperative cortisol, noradrenaline and total catecholamine levels were significantly lower in the SA group compared with the EA group. When pre- and intraoperative values were compared, the SA group showed a decrease in adrenaline, noradrenaline and total catecholamine levels, and the EA group showed an increase in ACTH and noradrenaline levels. CONCLUSIONS: The type of regional anaesthesia significantly affected the stress response: spinal anaesthesia produced a more favourable endocrine response than epidural anaesthesia. Spinal-general anaesthesia may reduce postoperative morbidity in laparoscopic cholecystectomy
http://www.jimronline.net/content/full/2012/108/1905.pdf
Efectos similares sobre la respuesta perioperatoria al estrés de los pacientes hemorroidectomizados bajo anestesia espinal o general
Similar effects of general and spinal anaesthesia on perioperative stress response in patients undergoing haemorrhoidectomy.
Buyukkocak U, Caglayan O, Daphan C, Aydinuraz K, Saygun O, Agalar F.
Department of Anaesthesiology and Reanimation, School of Medicine, Kirikkale Univeristy, 71100 Kirikkale, Turkey.
Mediators Inflamm. 2006;2006(1):97257.
Abstract
Surgery induces release of neuroendocrine hormones (cortisol), cytokines (interleukin-6: IL-6, tumour necrosis factor-alpha: TNF-alpha), acute phase proteins (C-reactive protein: CRP, leptin). We studied the effects of general and spinal anaesthesia on stress response to haemorrhoidectomy. Patients were assigned to general and spinal anaesthesia groups (n = 7). Blood samples were drawn before induction and 24 hours after surgery. Perioperative levels of IL-6, TNF-alpha, CRP, cortisol, and leptin were comparable among the groups. Twenty four hours after surgery, TNF-alpha and cortisol did not change; IL-6 and CRP increased significantly in all patients. Significant increase in leptin levels was found in patients undergoing spinal anaesthesia. Except for the increase in leptin levels, there was no significant difference related to the effects of general and spinal anaesthesia.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570390/pdf/MI2006-97257.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570390/
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Spinal-general anaesthesia decreases neuroendocrine stress response in laparoscopic cholecystectomy.
Calvo-Soto P, Martínez-Contreras A, -Hernández BT, And FP, Vásquez C.
Department of Anaesthesia, General Family Medicine and Zone Hospital No. 1, Mexican Social Security Institute, Colima, Mexico.
J Int Med Res. 2012;40(2):657-65.
Abstract
OBJECTIVE: A randomized clinical study to compare the stress response to laparoscopic cholecystectomy during spinal-general anaesthesia and epidural- general anaesthesia. METHODS: Women undergoing elective laparoscopic chole cystectomy were assigned to receive either spinal anaesthesia (SA group; n = 12) or epidural anaesthesia (EA group; n = 12), in addition to general anaesthesia. Plasma concentrations of cortisol, adrenocorticotrophic hormone (ACTH), noradrenaline, adrenaline and total catecholamines were measured pre- and intraoperatively. RESULTS: Intraoperative cortisol, noradrenaline and total catecholamine levels were significantly lower in the SA group compared with the EA group. When pre- and intraoperative values were compared, the SA group showed a decrease in adrenaline, noradrenaline and total catecholamine levels, and the EA group showed an increase in ACTH and noradrenaline levels. CONCLUSIONS: The type of regional anaesthesia significantly affected the stress response: spinal anaesthesia produced a more favourable endocrine response than epidural anaesthesia. Spinal-general anaesthesia may reduce postoperative morbidity in laparoscopic cholecystectomy
http://www.jimronline.net/content/full/2012/108/1905.pdf
Efectos similares sobre la respuesta perioperatoria al estrés de los pacientes hemorroidectomizados bajo anestesia espinal o general
Similar effects of general and spinal anaesthesia on perioperative stress response in patients undergoing haemorrhoidectomy.
Buyukkocak U, Caglayan O, Daphan C, Aydinuraz K, Saygun O, Agalar F.
Department of Anaesthesiology and Reanimation, School of Medicine, Kirikkale Univeristy, 71100 Kirikkale, Turkey.
Mediators Inflamm. 2006;2006(1):97257.
Abstract
Surgery induces release of neuroendocrine hormones (cortisol), cytokines (interleukin-6: IL-6, tumour necrosis factor-alpha: TNF-alpha), acute phase proteins (C-reactive protein: CRP, leptin). We studied the effects of general and spinal anaesthesia on stress response to haemorrhoidectomy. Patients were assigned to general and spinal anaesthesia groups (n = 7). Blood samples were drawn before induction and 24 hours after surgery. Perioperative levels of IL-6, TNF-alpha, CRP, cortisol, and leptin were comparable among the groups. Twenty four hours after surgery, TNF-alpha and cortisol did not change; IL-6 and CRP increased significantly in all patients. Significant increase in leptin levels was found in patients undergoing spinal anaesthesia. Except for the increase in leptin levels, there was no significant difference related to the effects of general and spinal anaesthesia.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570390/pdf/MI2006-97257.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570390/
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
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