Muertes relacionadas con broncoaspiración en 57 pacientes consecutivos. Estudio en autopsias
Aspiration-related deaths in 57 consecutive patients: autopsy study.
Hu X, Yi ES, Ryu JH.
PLoS One. 2014 Jul 30;9(7):e103795. doi: 10.1371/journal.pone.0103795. eCollection 2014.
Abstract
BACKGROUND: Aspiration can cause a diverse spectrum of pulmonary disorders some of which can lead to death but can be difficult to diagnose. PATIENTS AND METHODS: The medical records and autopsy findings of 57 consecutive patients in whom aspiration was the immediate cause of death at Mayo Clinic (Rochester, MN, USA) over a 9-yr period, from January 1 2004 to December 31 2012 were analyzed. RESULTS: The median age at death was 72 years (range, 13-95 years) and included 39 (68%) males. The most common symptom before death was dyspnea (63%) and chest radiography revealed bilateral infiltrates in the majority (81%). Most common precipitating factors for aspiration were depressed consciousness (46%) and dysphagia (44%). Aspiration-related syndromes leading to death were aspiration pneumonia in 26 (46%), aspiration pneumonitis in 25 (44%), and large airway obstruction in 6 patients (11%). Aspiration was clinically unsuspected in 19 (33%) patients. Antimicrobial therapy had been empirically administered to most patients (90%) with aspiration pneumonia and aspiration pneumonitis. CONCLUSION: We conclude aspiration-related deaths occur most commonly in the elderly with identifiable risks and presenting bilateral pulmonary infiltrates. One-third of these aspiration-related pulmonary syndromes were clinically unsuspected at the time of death.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116222/pdf/pone.0103795.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Aspiration-related deaths in 57 consecutive patients: autopsy study.
Hu X, Yi ES, Ryu JH.
PLoS One. 2014 Jul 30;9(7):e103795. doi: 10.1371/journal.pone.0103795. eCollection 2014.
Abstract
BACKGROUND: Aspiration can cause a diverse spectrum of pulmonary disorders some of which can lead to death but can be difficult to diagnose. PATIENTS AND METHODS: The medical records and autopsy findings of 57 consecutive patients in whom aspiration was the immediate cause of death at Mayo Clinic (Rochester, MN, USA) over a 9-yr period, from January 1 2004 to December 31 2012 were analyzed. RESULTS: The median age at death was 72 years (range, 13-95 years) and included 39 (68%) males. The most common symptom before death was dyspnea (63%) and chest radiography revealed bilateral infiltrates in the majority (81%). Most common precipitating factors for aspiration were depressed consciousness (46%) and dysphagia (44%). Aspiration-related syndromes leading to death were aspiration pneumonia in 26 (46%), aspiration pneumonitis in 25 (44%), and large airway obstruction in 6 patients (11%). Aspiration was clinically unsuspected in 19 (33%) patients. Antimicrobial therapy had been empirically administered to most patients (90%) with aspiration pneumonia and aspiration pneumonitis. CONCLUSION: We conclude aspiration-related deaths occur most commonly in the elderly with identifiable risks and presenting bilateral pulmonary infiltrates. One-third of these aspiration-related pulmonary syndromes were clinically unsuspected at the time of death.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116222/pdf/pone.0103795.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
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