Revisiones_bibliográficas TyO_Web: Sepsis en el anciano / Sepsis in elderly patients

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lunes, 20 de marzo de 2017

Sepsis en el anciano / Sepsis in elderly patients

Marzo 19, 2017. No. 2633

Sepsis e inmuno senescencia en el paciente anciano. Una revisión

Sepsis and Immunosenescence in the Elderly Patient: A Review.

Martín S1, Pérez A1, Aldecoa C2.

Front Med (Lausanne). 2017 Feb 28;4:20. doi: 10.3389/fmed.2017.00020. eCollection 2017.

Abstract

Sepsis is a prevalent, serious medical condition with substantial mortality and a significant consumption of health-care resources. Its incidence has increased around 9% annually in general population over the last years and specially in aged patients group. Several risk factors such as comorbidities, preadmission status, malnutrition, frailty, and an impared function in the immune system called immunosenescence are involved in the higher predisposition to sepsis in the elderly patients. Immunosenescence status consists in a functional impairment in both cell-mediated immunity and humoral immune responses and increases not only the risk for develop sepsis but also lead to more severe presentation of infection and may be is also related with a higher mortality. There is a also a concern about to admit patients in the intensive care units taking into account that the outcome of elderly patients is poorer compared to younger people. Nevertheless, the management of septic elderly patients does not differ substantially from younger people. In addition, the quality of life in septic elderly survivors is also lower than in younger people. But age, as alone factor, should not be used to determine treatment options because the poorer outcomes is thought to be due to the increased comorbidities and frailty in this group of patients.

KEYWORDS: elderly patients; immunosenescence; outcome; quality of life; sepsis

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Disminución del músculo esquelético como factor de riesgo en ancianos con sepsis. Estudio retrospectivo de cohortes

Decreasing skeletal muscle as a risk factor for mortality in elderly patients with sepsis: a retrospective cohort study.

Shibahashi K1, Sugiyama K1, Kashiura M1, Hamabe Y1.

J Intensive Care. 2017 Jan 11;5:8. doi: 10.1186/s40560-016-0205-9. eCollection 2017.

Abstract

BACKGROUND: Older patients account for the majority of patients with sepsis. The objective of this study was to determine if decreased skeletal muscle mass is associated with outcomes in elderly patients with sepsis. ,, CONCLUSIONS: Less skeletal muscle mass is associated with higher in-hospital mortality in elderly patients with sepsis. The results of this study suggest that identifying patients with low muscularity contributes to better stratification in this population.

KEYWORDS: Intensive care; Mortality; Sarcopenia; Sepsis

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