domingo, 24 de febrero de 2013

Historia y algo más/History and more


http://www.smo.edu.mx/





Este mes en la historia de la anestesiología: Febrero
This Month in Anesthesia History: February
1723 February 25: Christopher Wren died in London. Around 1660 the English architect and astronomer began to experiment with the transfusion of blood between animals and intravenous injections into animals. An account of his work was published in the Philosophical Transactions of the Royal Society of London in 1665.  [see Bergman NA. Early intravenous anesthesia: an eyewitness account. Anesthesiology 72:185-186, 1990] Recent biographies of Wren include Lisa Jardine's On a Grander Scale: The Outstanding Life of Christopher Wren and Adrian Tinniswood's His Invention So Fertile: A Life of Christopher Wren.
http://ahahq.org/Calendar/February.php 

  
Un informe de la conferencia James Watson en la Universidad de Yale
A report of the James Watson lecture at Yale University.
Smith-Vikos T.
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA. thalyana.smith-vikos@yale.edu
Yale J Biol Med. 2012 Sep;85(3):417-9. Epub 2012 Sep 25.
Abstract
In March 2012, Nobel Prize winner James Watson gave a seminar at Yale University entitled "Driven by Ideas." In his lecture, Watson discussed his personal vision for the future of science, specifically addressing how the scientific community should approach developing anticancer agents. He discussed the use of glycolytic inhibitors as anticancer agents due to the Warburg effect, as well as the benefits of metformin and anti-inflammatory drugs to help prevent cancer. He also compared drugs that target cell proliferation instead of targeting cell growth. Additionally, Watson commented on the mechanisms for how research should be conducted in the laboratory.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447206/pdf/yjbm_85_3_417.pdf
 
 
Una conversación con Robert Lefkowitz, Joseph Goldstein y Michael Brown
A conversation with Robert Lefkowitz, Joseph Goldstein, and Michael Brown
Ushma S. Neill and Howard A. Rockman
J Clin Invest. 2012 May 1; 122(5): 1586-1587. Published online 2012 May 1. doi: 10.1172/JCI64244
Today we shift the format of our Conversations with Giants in Medicine and allow three of our most charismatic giants (Robert Lefkowitz, Joseph Goldstein, and Michael Brown) to interview each other. Lefkowitz (Duke University) is known for his seminal discoveries in understanding G protein-coupled receptor function. The legendary partnership between Brown and Goldstein (University of Texas Southwestern Medical Center) has spanned four decades. Together they were awarded the 1985 Nobel Prize in Physiology or Medicine acknowledging their discovery of the LDL cholesterol receptor and its role in the regulation of cholesterol metabolism. The full interview can be seen on the JCI website, http://www.jci.org/kiosk/cgm.

Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org

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