Plaquetas

Concentrado de plaquetas; pasado, presente y futuro  Platelet concentrates: past, present and future. Prakash S, Thakur A. J Maxillofac Oral Surg. 2011 Mar;10(1):45-9. Epub 2011 Feb 25. Abstract Platelets play a crucial role in hemostasis and wound healing, platelet growth factors are well known source of healing cytokines. Numerous techniques of autologous platelet concentrates have been developed and applied in oral and maxillofacial surgery. This review describes the evolution of the first and second generation of platelet concentrates (platelet rich plasma and platelet rich fibrin respectively) from their fore runner-fibrin sealants. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177496/?tool=pubmed http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177496/pdf/12663 _2011_Article_182.pdf    Función plaquetaria en diabéticos: desde la teoría a la perspectiva clínica  Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective. Kakouros N, Rade JJ, Kourliouros A, Resar JR. Johns Hopkins University School of Medicine, and Johns Hopkins Hospital Division of Cardiovascular Disease, Baltimore, MD 21287-073, USA. Int J Endocrinol. 2011;2011:742719. Epub 2011 Aug 21. Abstract Patients with diabetes mellitus have an increased prevalence of vascular disease. Pathologic thrombosis associated with atherosclerotic plaque rupture is a major cause of morbidity and mortality. Platelets are intimately involved in the initiation and propagation of thrombosis. Evidence suggests that platelets from patients with type 2 diabetes have increased reactivity and baseline activation compared to healthy controls. We review the pathophysiology of platelet hyperreactivity in DM patients and its implications in clinical practice, with particular focus on acute coronary syndromes, percutaneous coronary intervention, and novel antiplatelet agents. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159301/?tool=pubmed  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159301/pdf/IJE2011-742719.pdf

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