jueves, 31 de agosto de 2017

Envejecimiento y antienvejecimiento / Aging and anti-aging

Agosto 30, 2017. No. 2796





MECANISMOS EN ENDOCRINOLOGÍA: Envejecimiento y antienvejecimiento: una visión general en combo-endocrinología.
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Eur J Endocrinol. 2017 Jun;176(6):R283-R308. doi: 10.1530/EJE-16-1061. Epub 2017 Mar 6.
Abstract
Aging and its underlying pathophysiological background has always attracted the attention of the scientific society. Defined as the gradual, time-dependent, heterogeneous decline of physiological functions, aging is orchestrated by a plethora of molecular mechanisms, which vividly interact to alter body homeostasis. The ability of an organism to adjust to these alterations, in conjunction with the dynamic effect of various environmental stimuli across lifespan, promotes longevity, frailty or disease. Endocrine function undergoes major changes during aging, as well. Specifically, alterations in hormonal networks and concomitant hormonal deficits/excess, augmented by poor sensitivity of tissues to their action, take place. As hypothalamic-pituitary unit is the central regulator of crucial body functions, these alterations can be translated in significant clinical sequelae that can impair the quality of life and promote frailty and disease. Delineating the hormonal signaling alterations that occur across lifespan and exploring possible remedial interventions could possibly help us improve the quality of life of the elderly and promote longevity.



XIV Congreso Virtual Mexicano de Anestesiología 2017
Octubre 1-Diciembre 31, 2017
Información / Information
Convocatoria para el Curso de Posgrado en Medicina del Dolor y Paliativa 2018 para Mexicanos y extranjeros.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Informes (52) 55 5487 0900 ext. 5011 de lunes a viernes de 9.00 a 14 h (hora de Ciudad de México). 
XXXIV Congreso Latinoamericano de Anestesiología. CLASA 2017
Octubre 8-11. Uruguay
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Anestesiología y Medicina del Dolor

52 664 6848905

Ligamento colateral medial del codo


Basic Sciences – Anatomy of the Elbow Medial Collateral Ligament
Fuente
Este artículo y/o video es originalmente publicado en:
De y todos los derechos reservados para:
Courtesy: Harry Benjamin Laing MRCS, Ortho M8, FRCS(Tr and Orth) Tutorials


Migraña / Migraine

Agosto 31, 2017. No. 2797







Investigación premiada por el Comité Editorial de Cefalalgia como el artículo más impactante en el campo de las cefaleas.
This prestigious award is given to the paper which the Cephalalgia Editorial Board considers to be the most impactful paper in the field of headache medicine to be published in the Journal.
Este prêmio de prestígio é dado ao artigo que o Conselho Editorial da Cephalalgia considera ser o documento mais impactante no campo do medicamento para dor de cabeça para ser publicado no Jornal.
Micropartículas circulantes en mujeres migrañosas con aura
Circulating endothelial microparticles in female migraineurs with aura.
Cephalalgia. 2015 Feb;35(2):88-94. doi: 10.1177/0333102414529671. Epub 2014 Apr 8.
Abstract
BACKGROUND AND PURPOSE: Endothelial microparticles (EMPs) are vesicles that are released from activated endothelial cells and serve as a surrogate for endothelial dysfunction (ED). ED may be involved in migraine pathophysiology and contribute to the increased risk of ischemic stroke, particularly in female migraineurs with aura (MA). We sought to determine whether EMPs are elevated in women with MA.
CONCLUSION: EMP levels are significantly elevated in women with MA and correlated with increased AI. Our findings suggest that endothelial activation is present in women with MA. This might contribute to higher stroke risk in MA.
KEYWORDS: Endothelial microparticle; endothelial dysfunction; migraine; stroke risk



XIV Congreso Virtual Mexicano de Anestesiología 2017
Octubre 1-Diciembre 31, 2017
Información / Information
Convocatoria para el Curso de Posgrado en Medicina del Dolor y Paliativa 2018 para Mexicanos y extranjeros.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Informes (52) 55 5487 0900 ext. 5011 de lunes a viernes de 9.00 a 14 h (hora de Ciudad de México). 
XXXIV Congreso Latinoamericano de Anestesiología. CLASA 2017
Octubre 8-11. Uruguay
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Anestesiología y Medicina del Dolor

52 664 6848905

lunes, 28 de agosto de 2017

Neuronas adictivas / Addictive neurons.

Agosto 28, 2017. No. 2794






Neuronas adictivas
Addictive neurons.
Kodirov SA1,2,3,4,5.
Ther Targets Neurol Dis. 2017;4. pii: e1498. Epub 2017 Jan 30.
Abstract
Since the reward center is considered to be the area tegmentalis ventralis of the hypothalamus, logically its neurons could mainly be responsible for addiction. However, the literature asserts that almost any neurons of CNS can respond to one or another addictive compound. Obviously not only addictive nicotine, but also alcohol, amphetamine, cannabis, cocaine, heroin and morphine may influence dopaminergic cells alone in VTA. Moreover, paradoxically some of these drugs ameliorate symptoms, counterbalance syndromes, cure diseases and improve health, not only those related to the CNS and in adults, but also almost all other organs and in children, e.g. epilepsy.
KEYWORDS: ADP; AHP; LTD; LTP; amygdala; lateral septum; medial prefrontal cortex; paired pulse facilitation; rebound action potential; spike



XIV Congreso Virtual Mexicano de Anestesiología 2017
Octubre 1-Diciembre 31, 2017
Información / Information
Convocatoria para el Curso de Posgrado en Medicina del Dolor y Paliativa 2018 para Mexicanos y extranjeros.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Informes en el teléfono (52) 55 5487 0900 ext. 5011 de lunes a viernes de 9.00 a 14 h (hora de México). 
XXXIV Congreso Latinoamericano de Anestesiología. CLASA 2017
Octubre 8-11. Uruguay
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Anestesiología y Medicina del Dolor

52 664 6848905

De médico....la mala letra

El Doctor Benjamín Joel Torres Fernandez invita: