| Adyuvantes analgésicos en dolor por cáncer: Una revisión |
Adjuvant Analgesics in Cancer Pain: A Review
Raj Mitra, Stephanie Jones
AM J HOSP PALLIAT CARE 2012 29: 70
Abstract
Adjuvant analgesics (co-analgesics) are medications whose primary indication is the management of a medical condition with secondary effects of analgesia. Cancer pain is multifactorial and often involves inflammatory, nociceptive, and neuropathic pain subtypes. Adjuvant analgesics used in conjunction with opioids have been found to be beneficial in the management of many cancer pain syndromes; however, they are currently underutilized. Antidepressants, anticonvulsants, local anesthetics, topical agents, steroids, bisphosphonates, and calcitonin are all adjuvants which have been shown to be effective in the management of cancer pain syndromes. When utilizing analgesic adjuvants in the treatment of cancer pain, providers must take into account the particular side effect profile of the medication. Ideally, adjuvant analgesics will be initiated at lower dosages and escalated as tolerated until efficacy or adverse effects are encountered.
Keywords: adjuvant, analgesic, cancer and pain
http://ajh.sagepub.com/content/29/1/70.full.pdf+html
|
| Tratamiento clínico del dolor en cáncer avanzado del pulmón |
Clinical management of pain in advanced lung cancer.
Simmons CP, Macleod N, Laird BJ.
Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. EH4 2XR.
Clin Med Insights Oncol. 2012;6:331-46. doi: 10.4137/CMO.S8360. Epub 2012 Oct 8.
Abstract
Lung cancer is the most common cancer in the world and pain is its most common symptom. Pain can be brought about by several different causes including local effects of the tumor, regional or distant spread of the tumor, or from anti-cancer treatment. Patients with lung cancer experience more symptom distress than patients with other types of cancer. Symptoms such as pain may be associated with worsening of other symptoms and may affect quality of life. Pain management adheres to the principles set out by the World Health Organization's analgesic ladder along with adjuvant analgesics. As pain can be caused by multiple factors, its treatment requires pharmacological and non-pharmacological measures from a multidisciplinary team linked in with specialist palliative pain management. This review article examines pain management in lung cancer.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474460/pdf/cmo-6-2012-331.pdf
|
| Papel de los corticosteroides en el manejo del dolor de los pacientes con cáncer |
The role of corticosteroids in the treatment of pain in cancer patients.
Leppert W, Buss T.
Department of Palliative Medicine, Poznan University of Medical Sciences, Poland. wojciechleppert@wp.pl
Curr Pain Headache Rep. 2012 Aug;16(4):307-13. doi: 10.1007/s11916-012-0273-z.
Abstract
Pain is one of the most frequent and most distressing symptoms in the course of cancer. The management of pain in cancer patients is based on the concept of the World Health Organization (WHO) analgesic ladder and was recently updated with the EAPC (European Association for Palliative Care) recommendations. Cancer pain may be relieved effectively with opioids administered alone or in combination with adjuvant analgesics. Corticosteroids are commonly used adjuvant analgesics and play an important role in neuropathic and bone pain treatment. However, in spite of the common use of corticosteroids, there is limited scientific evidence demonstrating their efficacy in cancer patients with pain. The use of corticosteroids in spinal cord compression, superior vena cava obstruction, raised intracranial pressure, and bowel obstruction is better established than in other nonspecific indications. This review aims to present the role of steroids in pain and management of other symptoms in cancer patients according to the available data, and discusses practical aspects of steroid use.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395343/pdf/11916_2012_Article_273.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
|
|
No hay comentarios:
Publicar un comentario