Alergia y anestesia / Allergy and anesthesia

Octubre 25, 2017. No. 2892

Alergia a las benzodiazepinas con administración de anestesia: revisión de la literatura actual. Benzodiazepine Allergy With Anesthesia Administration: A Review of Current Literature. Haybarger E1, Young AS2, Giovannitti JA Jr3. Author information Anesth Prog. Fall 2016;63(3):160-7. doi: 10.2344/16-00019.1. Abstract The incidence of anaphylactic/anaphylactoid reactions has been reported to vary between 1:3500 and 1:20,000 cases with a mortality rate ranging from 3 to 9%. Clinical signs present as skin rash, urticaria, angioedema, bronchospasm, tachycardia, bradycardia, and hypotension. Rapid identification and treatment are crucial to overall patient prognosis, as delayed intervention is associated with increased mortality. Diagnosis may be confirmed with clinical presentation, serum tryptase levels, and skin test results. While the main causative agents in anesthetic practice are typically neuromuscular blocking agents (NMBs), latex, and antibiotics, this review aims to discuss recognition, management, and preventive measures in perioperative anaphylactic/anaphylactoid reactions from benzodiazepine administration. KEYWORDS: Anaphylactoid reactions; Anaphylaxis; Benzodiazepine allergy; Diagnosis of anaphylaxis; Management of anaphylaxis PDF Hipersensibilidad a los anestésicos locales Hypersensitivity to local anesthetics. Grzanka A, Wasilewska I, Śliwczyńska M, Misiołek H1. Author information Anaesthesiol Intensive Ther. 2016;48(2):128-34. doi: 10.5603/AIT.a2016.0017. Epub 2016 Mar 15. Abstract Using local anaesthetics in daily practice, particularly by anaesthetists and dentists, is connected with the risk of side effects. Therefore, the observation of side effects, carrying out detailed research (according to the chart proposed in this study) and conducting specialist examinations is of the highest importance. There is a variety of side effects that could occur during local anaesthesia procedures, with the intensity ranging from clinically unimportant to life threatening. Clinicians' major concerns are the appearance of various hypersensitivity reactions, including anaphylaxis. Healthcare providers responsible for the administration of local anaesthetics should be able to detect hypersensitivity reactions to implement appropriate treatment and then choose highly selected diagnostic procedures. The final diagnosis should be based on specific medical history; documentation, including a description of the case and measurement of tryptase activity; skin tests; and provocation trials. Screening tests are not recommended in populations without hypersensitivity to local anaesthestics in their medical history. KEYWORDS: hypersensitivity; local anestehtics; local anesthesia; skin tests PDF XXVII Congreso Peruano de Anestesiología Lima, Noviembre 2-4, 2017 Informes / Informataion

Anestesiología y Medicina del Dolor 52 664 6848905 vwhizar@anestesia-dolor.org anestesia-dolor.org