sábado, 28 de mayo de 2011

Trombocitopenia en el embarazo


Trombocitopenia en el embarazo
Thrombocytopenia in pregnancy.
McCrae KR.
Source
Cleveland Clinic Foundation, Cleveland, OH 44195, USA. mccraek@ccf.org
Hematology Am Soc Hematol Educ Program. 2010;2010:397-402.
Abstract
Thrombocytopenia occurs commonly during pregnancy, and may result from diverse etiologies. Awareness of these many causes facilitates proper diagnosis and management of thrombocytopenia in the pregnant setting. Some causes of thrombocytopenia are unique to pregnancy and may not be familiar to hematologists. In the review, we will discuss the differential diagnosis of thrombocytopenia in pregnancy, and the pathogenesis of selected thrombocytopenic disorders. Considerations for optimal management of the pregnant patient with thrombocytopenia will also be described.

Experiencias de las mujeres eclámpticas: Encuesta de las acciones Australianas de las mujeres y sus confidentes
Women's Experiences of Preeclampsia: Australian Action on Preeclampsia Survey of Women and Their Confidants.
East C, Conway K, Pollock W, Frawley N, Brennecke S.
Source
Department of Obstetrics & Gynaecology, The University of Melbourne and Department of Perinatal Medicine, Royal Women's Hospital, 20 Flemington Road, Parkville, VIC 3052, Australia.
J Pregnancy. 2011;2011:375653. Epub 2011 Mar 23.
Abstract
Introduction. The experience of normal pregnancy is often disrupted for women with preeclampsia (PE). Materials and Methods. Postal survey of the 112 members of the consumer group, Australian Action on Pre-Eclampsia (AAPEC). Results. Surveys were returned by 68 women (61% response rate) and from 64 (57%) partners, close relatives or friends. Respondents reported experiencing pre-eclampsia (n = 53), eclampsia (n = 5), and/or Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP syndrome) (n = 26). Many women had no knowledge of PE prior to diagnosis (77%) and, once diagnosed, did not appreciate how serious or life threatening it was (50%). Women wanted access to information about PE. Their experience contributed substantial anxiety towards future pregnancies. Partners/friends/relatives expressed fear for the woman and/or her baby and had no prior understanding of PE. Conclusions. The PE experience had a substantial effect on women, their confidants, and their babies and affected their approach to future pregnancies. Access to information about PE was viewed as very important
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087153/pdf/JP2011-375653.pdf  
Evolución materna del síndrome de HELLP que requirió manejo en UCI en un hospital turco.
Maternal outcome in HELLP syndrome requiring intensive care management in a Turkish hospital.
Osmanagaoglu MA, Osmanagaoglu S, Ulusoy H, Bozkaya H.
Source
Sao Paulo Med J. 2006 Mar 2;124(2):85-9.

Department of Obstetrics and Gynecology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey. osmanaga@meds.ktu.edu.tr
Abstract
CONTEXT AND OBJECTIVE: Despite the development of tertiary care facilities, intensive care and advanced blood banking techniques, pregnancy-related hypertensive disorders are the main cause of maternal mortality in most countries. Our purpose was to determine maternal outcome in pregnancies complicated by HELLP syndrome (hemolysis, elevated liver enzymes and low platelet count) that required intensive care management. DESIGN AND SETTING: Retrospective study at Department of Obstetrics and Gynecology, and Department of Anesthesiology and Reanimation, Karadeniz Technical University, Trabzon, Turkey.
METHODS: 37 patients with HELLP syndrome admitted to the obstetric intensive care unit were analyzed retrospectively from 1992 to 2004. RESULTS: All patients were hypertensive, with mean Glasgow coma score (GCS) of 11 +/- 3.96. Mean gestational age at delivery was 32 +/- 4.09 weeks. Delivery was vaginally in nine and by cesarean section in 27 patients. General anesthesia was used in 12 and spinal anesthesia in 25 patients. Maternal morbidity included acute renal failure (11%), disseminated intravascular coagulation (5%), acute lung edema (3%), severe ascites (11%), pleural effusion (3%), adult respiratory distress syndrome (11%), abruptio placenta (11%), cerebral edema (8%) and cerebral hemorrhage (40%). All patients required transfusions using blood products. There were 11 maternal deaths (30%). CONCLUSION:
Because of high maternal mortality and morbidity found among patients with HELLP syndrome, standard antenatal follow-up protocols should be applied, so as to obtain early diagnosis and improve the speed of transfer to obstetric departments with expertise in this field
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Atentamente
Dr. Benito Cortes-Blanco 
Anestesiología y Medicina del Dolor

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