Dexmedetomidina / Dexmedetomidine

Enero 19, 2017. No. 2574

Eficacia de la dexmedetomidina-remifentanil versus dexmedetomidina-propofol en niños programados para broncoscopía flexible The efficacy of dexmedetomidine-remifentanil versus dexmedetomidine-propofol in children undergoing flexible bronchoscopy: A retrospective trial. Zhang H1, Fang B, Zhou W. Medicine (Baltimore). 2017 Jan;96(1):e5815. doi: 10.1097/MD.0000000000005815. Abstract Flexible bronchoscopy has been more and more used for diagnosis and management diseases of respiratory system in pediatrics. Previous studies have reported that remifentanil (RF) and propofol are safe and effective for flexible bronchoscopy in adults, however, there have no trials evaluate the efficacy of DEX-RF versus dexmedetomidine-propofol in children undergoing flexible bronchoscopy. DEX-RF resulted in more stable hemodynamic profiles and bronchoscopist-satisfaction scores, lesser patient movements, and can hence be more effectively used in children undergoing flexible bronchoscopy than dexmedetomidine-propofol. PDF Dexmedetomidina previene nausea y vomito postoperatorios en pacientes con anestesia general Dexmedetomidine prevent postoperative nausea and vomiting on patients during general anesthesia: A PRISMA-compliant meta analysis of randomized controlled trials. Jin S1, Liang DD, Chen C, Zhang M, Wang J. Medicine (Baltimore). 2017 Jan;96(1):e5770. doi: 10.1097/MD.0000000000005770. Abstract BACKGROUND: Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of this article was to evaluate the effect of dexmedetomidine on PONV.  CONCLUSIONS: Dexmedetomidine administrated in continuous infusion mode has the advantage to prevent PONV as well as reduce side effects such as bradycardia and hypotension. PDF Uso de alfa2 agonistas en neuroanestesia. Una revisión Use of α(2)-Agonists in Neuroanesthesia: An Overview. Farag E, Argalious M, Sessler DI, Kurz A, Ebrahim ZY, Schubert A. Ochsner J. 2011 Spring;11(1):57-69. Abstract α(2)-Agonists are a novel class of drugs with mechanisms of action that differ from other commonly used anesthetic drugs. They have neuroprotective, cardioprotective, and sedative effects. These unique characteristics make them potentially useful during neuroanesthesia and intensive care. We review the effects of dexmedetomidine on cerebral blood flow and cerebral metabolism, along with recent advances in using α(2)-agonists in neuroanesthesia and neurointensive care. KEYWORDS: Alpha-2 agonist; anesthesia; dexmedetomidine; neuroanesthesia; neuroprotection PDF

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