martes, 18 de julio de 2017

Enfermedades cardiovasculares y diabetes / Cardiovascular disease and diabetes

Julio 15, 2017. No. 2750






Enfermedades cardiovasculares y diabetes. ¡Dos caras de la misma moneda!
Cardiovascular Disease and Diabetes: Two Sides of the Same Coin!
Sayeeda Rahman, Md. Anwarul Azim Majumder, Russell Kabir, Mainul Haque, Subir Gupta, Sana Mohammad Yasir Arafat, Nkemcho Ojeh and Prasad Dalvi
Recent Trends in Cardiovascular Risks
Abstract
Cardiovascular disease (CVD) and type 2 diabetes (T2DM) are rapidly rising around the globe. Empirical researches demonstrated rapid increase in mortality and morbidity related to CVD and T2DM. Much of the diabetes-associated morbidity and mortality predominantly reflects its deleterious effect on macrovascular and microvascular diseases. The microvascular complications of T2DM include retinopathy, neuropathy and nephropathy and the macrovascular complications include ischemic heart disease, cerebrovascular disease and peripheral vascular diseases. Research indicates that coronary heart disease (CHD) is the major cause of mortality in people with T2DM. Herein, this chapter reviews relationship between CVD and T2DM, associated complications and effectiveness of relevant treatment modalities to treat/prevent diabetic macrovasculopthy. Macrovascular disease occur due to underlying obstructive atherosclerotic changes of major arteries which cause functional and structural abnormalities of blood vessels. The long-term complications can be controlled and prevented by controlling glycemia, maintaining normal lipid profiles, adopting a healthy lifestyle and using pharmacological interventions. Clinical trials have shown that lifestyle interventions help in prevention and reduction of CVD risk, but evidence for long-term CVD outcomes is lacking. A multidisciplinary approach involving patients, health professionals and researchers and governments should be undertaken to reduce the incidence and prevalence of diabetesrelated cardiovascular complications. Keywords: cardiovascular diseases, type 2 diabetes, vasculopathy, macrovascular diseases, atherosclerosis, pathophysiology, pathogenesis

Refinación de la predicción a largo plazo del riesgo cardiovascular en la diabetes - La puntuación de VILDIA.
Refining Long-Term Prediction of Cardiovascular Risk in Diabetes - The VILDIA Score.
Sci Rep. 2017 Jul 5;7(1):4700. doi: 10.1038/s41598-017-04935-8.
Abstract
Cardiovascular risk assessment in patients with diabetes relies on traditional risk factors. However, numerous novel biomarkers have been found to be independent predictors of cardiovascular disease, which might significantly improve risk prediction in diabetic patients. .... The VILDIA score based on traditional cardiovascular risk factors and reinforced with novel biomarkers outperforms previous risk algorithms.

XIV Congreso Virtual Mexicano de Anestesiología 2017
Octubre 1-Diciembre 31, 2017
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