lunes, 12 de marzo de 2018

LIbro sobre trombocitopenia / Book on thrombocytopenia

Marzo 12, 2018. No. 3020
Edited by Pankaj Abrol, ISBN 978-953-51-3876-1, Print ISBN 978-953-51-3875-4, 104 pages, Publisher: InTech, Chapters published March 07, 2018 under CC BY 3.0 license
DOI: 10.5772/intechopen.69080
Edited Volume
The book "Thrombocytopenia" certainly raises some important issues in its pathogenesis and management. The authors have done a lot of hard work to write state-of-the-art chapters. Each and every chapter is peer-reviewed, evidence-based, and remarkably excellent. Some of the causes of thrombocytopenia are well explained in textbooks, but the topics included in this book are not usually so well described. The chapters are written in such a manner so as to stimulate and keep the reader well-informed. Such an approach is certainly beneficial when aiming to motivate discussion, interaction, innovation, and research. Chapters like "Interferon-Induced Thrombotic Microangiopathy" have been included with the aim to help in understanding the immune pathogenesis of thrombocytopenia. Others have also been selected to keep an eye on the future.
La fisiopatología de las plaquetas sanguíneas y la sepsis: ¿una nueva perspectiva terapéutica en pacientes críticos?
Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
Erratum in
Ann Intensive Care. 2017 Dec 1;7(1):115. doi: 10.1186/s13613-017-0337-7.
Beyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened the spectrum of their role in health and disease. Here, we propose a narrative review that first describes these new platelet attributes. We then examine their relevance to microcirculatory alterations in multi-organ dysfunction, a major sepsis complication. Rapid progresses that are made on the knowledge of novel platelet functions should improve the understanding of thrombocytopenia, a common condition and a predictor of adverse outcome in sepsis, and may provide potential avenues for management and therapy.
KEYWORDS: Inflammation; Intensive care; Platelets; Sepsis
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