miércoles, 24 de agosto de 2016

Dexmedetomidina i.v. y raquia / I.V. dexmedetomidine and spinal anesthesia

Agosto 24, 2016. No. 2427

Dosis única de dexmedetomidina intravenosa prolonga la anestesia espinal con bupivacaína hiperbárica
Single dose intravenous dexmedetomidine prolongs spinal anesthesia with hyperbaric bupivacaine.
Anesth Essays Res. 2016 May-Aug;10(2):273-7. doi: 10.4103/0259-1162.174465.
BACKGROUND AND INTRODUCTION: Spinal block, a known technique to obtain anaesthesia for infraumblical surgeries. Now physician have advantage of using adjuvant to prolong the effect of intrathecal block, which can be given either intravenously or intrathecally, dexmedetomidine is one of them. We studied effect of intravenous dexmedetomidine for prolongation of duration of intrathecal block of 0.5% bupivacaine block. OBJECTIVE: To evaluate the effect of intravenous dexmedetomidine on sensory regression, hemodynamic profile, level of sedation and postoperative analgesia. METHODOLOGY: 60 patients of ASA grade I and II posted for elective infraumblical surgeries were included in the study and randomly allocated into two groups. Group D recieved intrathecal 0.5% bupivacaine heavy, followed by infusion ofintravenous dexmedetomidine 0.5mic/kg over 10 min, patients in group C received intrathecal 0.5% bupivacaine heavy 3ml followed by infusion of same volume of normal saline as placebo. RESULTS: Two segment regression of sensory block was achieved at 139.0 ± 13.797 in group D whereas in group C it was only 96.67 ± 7.649min, the total duration of analgesia achieved in both study groups was 234.67 ± 7.649min and 164.17 ± 6.170min respectively in group D and group C. The time at which first analgesic was given to the patients when VAS >3 achieved that is in group D at 234.67 ± 7.649min and in group C at 164.17 ± 6.170min. Inj diclofenac sodium 75mg intramuscular was used as rescue analgesic.
KEYWORDS: Intravenous dexmedetomidine; postoperative analgesia; sensory regression; spinal block

XIII Congreso Virtual Mexicano de Anestesiología
Octubre a Diciembre 2016

Información / Information
XXXVI Reunión Anual y Congreso Internacional de la Asociación Mexicana para Estudio y Tratamiento del Dolor
Querétaro, México, Octubre 16-22, 2016

16th World Congress of Anaesthesiologists

28 August - 2 September 2016 
Hong Kong Convention and Exhibition Centre
World Federation of Societies of Anaesthesiologists
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Anestesiología y Medicina del Dolor

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