lunes, 27 de julio de 2015

Más de sugammadex/More on sugammadex

Beneficios y riesgos de sugammadex
Benefits and risks of sugammadex.
Korean J Anesthesiol. 2015 Feb;68(1):1-2. doi: 10.4097/kjae.2015.68.1.1.
Uso de sugammadex en un paciente con syndrome de Wolff-Parkinson-White
Sugammadex Use in a Patient with Wolff-Parkinson-White (WPW) Syndrome.
Balkan Med J. 2015 Jul;32(3):327-9. doi: 10.5152/balkanmedj.2014.15155. Epub 2015 Jul 1.
Abstract
BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a disease associated with episodes of supraventricular tachycardia and ventricular pre-excitation or atrial fibrillation. WPW is characterized by an aberrant electrical conduction pathway between atria and ventricles. CASE REPORT: The major anesthetic problem connected with WPW syndrome is the risk of tachyarrhythmias due to accessory pathway. Therefore, it has been proposed that the aim of anesthetic management should be the avoidance of tachyarrhythmia and sympathetic stimulation.Sugammadex was administered as a neuromuscular reversal agent in this case. To our knowledge, this is the first case report of sugammadex use in a patient with WPW. This report presents a case of general anesthesia management in a patient with WPW syndrome.CONCLUSION: We think that it is appropriate to use sugammadex to reverse rocuronium for the prevention of sudden hemodynamic changes in patients with WPW who underwent general anesthesia.
KEYWORDS: General anesthesia; Wolff-Parkinson-White syndrome; sugammadex
Un milagro que acelera la funcionalidad de la sala de operaciones: Sugammadex
A miracle that accelerates operating room functionality: sugammadex.
Biomed Res Int. 2014;2014:945310. doi: 10.1155/2014/945310. Epub 2014 Aug 14.
Abstract
BACKGROUND: Sugammadex offers a good alternative to the conventional decurarisation process currently performed with cholinesterase inhibitors. Sugammadex, which was developed specifically for the aminosteroid-structured rocuronium and vecuronium neuromuscular blockers, is a modified cyclodextrin made up of 8 glucose monomers arranged in a cylindrical shape. METHODS: In this study, the goal was to investigate the efficacy of sugammadex. Sugammadex was used when there was insufficient decurarisation following neostigmine. This study was performed on 14 patients who experienced insufficient decurarisation (TOF <0.9) with neostigmine after general anaesthesia in the operating rooms of a university and a state hospital between June, 2012, and January, 2014. A dose of 2mg/kg of sugammadex was administered. RESULTS: Time elapsed until sugammadex administration following neostigmine 37 ± 6 min, following sugammadex it took 2.1 ± 0.9 min to reach TOF ≥0.9, and the extubation time was 3.2 ± 1.4 min. No statistically significant differences were detected in the hemodynamic parameters before and after sugammadex application. From the time of administration of sugammadex to the second postoperative hour, no side effects or complications occurred. None of the patients experienced acute respiratory failure or residual block during this time period. CONCLUSION: Sugammadex was successfully used to reverse rocuronium-induced neuromuscular block in patients where neostigmine was insufficient.
Sugammadex y peso ideal en cirugía bariátrica
Sugammadex and ideal body weight in bariatric surgery.
Anesthesiol Res Pract. 2013;2013:389782. doi: 10.1155/2013/389782. Epub 2013 Jun 6.
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Anestesia y Medicina del Dolor
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