Clonidina IT en cesárea/Spinal clonidine in C-section

Prevención de hipotensión y prolongación de analgesia postoperatoria en cesárea urgente: Estudio randomizado con clonidina intratecal


Prevention of hypotension and prolongation of postoperative analgesia in emergency cesarean sections: A randomized study with intrathecal clonidine.
Bajwa SJ, Bajwa SK, Kaur J, Singh A, Singh A, Parmar SS.
Department of Anesthesiology and Intensive Care Medicine, Gian Sagar Medical College and Hospital, Banur, Punjab, India.
Int J Crit Illn Inj Sci. 2012 May;2(2):63-9. doi: 10.4103/2229-5151.97269.
Abstract
BACKGROUND AND CONTEXT: Different adjuvants been tried out for neuraxial anesthesia in emergency caesarean section so that the dose of the local anesthetic can be reduced and hypotension thereby prevented. AIMS AND OBJECTIVES:The present study was carried out in patients presenting for emergency lower segment caesarean section (LSCS) to establish the dose of intrathecal clonidine that would allow reduction of the dose of local anesthetic (thereby reducing the incidence and magnitude of hypotension) while at the same time providing clinically relevant prolongation of spinal anesthesia without significant side effects.
MATERIALS AND METHODS: This randomized clinical study was carried out in our institution among 100 pregnant females who underwent emergency caesarean section. The participants were divided randomly into four groups: A, B, C, and D, each comprising 25 parturients. Subarachnoid block was performed using a 26G Quincke needle, with 12 mg of hyperbaric bupivacaine (LA) in group A, 9 mg of LA + 30 μg ofclonidine in group B, LA + 37.5 μg of clonidine in group C, and LA + 45 μg of clonidine in group D. The solution was uniformly made up to 2.2 mL with normal saline in all the groups. Onset of analgesia at T(10) level, sensory and motor blockade levels, maternal heart rate and blood pressure, neonatal Apgar scores, postoperative block characteristics, and adverse events were looked for and recorded. Statistical analysis was carried out with SPSS(®) version 10.0 for Windows(®), using the ANOVA test with post hoc significance, the Chi-square test, and the Mann-Whitney U test. P<.05 was considered significant and P<.0001 as highly significant. RESULTS: One hundred patients were enrolled for this study. The four groups were comparable with regard to demographic data and neonatal Apgar scores. Onset and establishment of sensory and motor analgesia was significantly shorter in groups C and D, while hypotension (and the use of vasopressors) was significantly higher in groups A and D. Perioperative shivering, nausea, and vomiting were significantly higher in groups A and D, while incidence of dry mouth was significantly higher in group D. CONCLUSIONS:The addition of 45 μg, 37.5 μg, and 30 μg of clonidine to hyperbaric bupivacaine results in more prolonged complete and effective analgesia, allowing reduction of up to 18% of the total dose of hyperbaric bupivacaine. From the results of this study, 37.5 μg of clonidine seems to be the optimal dose.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401819/






Efecto de clonidina intratecal agregada a bupivacaína hiperbárica sobre el dolor postoperatorio después de cesárea. Estudio randomizado controlado

The effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain after lower segment caesarean section: A randomized control trial.

Singh R, Gupta D, Jain A.

Department of Anaesthesiology and Critical Care, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.

Saudi J Anaesth. 2013 Jul;7(3):283-90. doi: 10.4103/1658-354X.115360.

Abstract

BACKGROUND:Intrathecal clonidine prolongs spinal anesthesia but the optimum dose to be used in cesarean delivery is not yet known. We evaluated the effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain after lower segment caesarean section. METHODS:A total of 105 parturients carrying a singleton fetus at term, scheduled to undergo elective LSCS under spinal anesthesia were randomized in a double blind fashion to one of the three groups. Group BF (n=35) received 2 ml of 0.5% hyperbaric bupivacaine+25 μg fentanyl, Group BC50 (n=35) received 2 ml of 0.5% hyperbaric bupivacaine+50 μg clonidine, Group BC75 (n=35) received 2 ml of 0.5% hyperbaric bupivacaine+75 μg clonidine. RESULTS:The duration of postoperative analgesia was 184.73±68.64 min in group BF, 360.71±86.51 min in group BC50 and 760.50±284.03 min in group BC75, P<0.001. The incidence of hypotension was comparable, P=0.932, whereas the incidence of nausea and pruritis was significantly lower in groups BC50 and BC75 as compared to group BF, P<0.001. No other side effects of intrathecal clonidine were detected. Neonatal outcome was similar in all the three groups. CONCLUSIONS:Addition of 75 μg clonidine to hyperbaric bupivacaine in spinal anesthesia for LSCS significantly prolongs the duration of postoperative analgesia without any increase in maternal side effects. There was no difference in neonatal outcome.

KEYWORDS:Caesarean section, clonidine, intrathecal, postoperative pain

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757801/


http://www.saudija.org/downloadpdf.asp?issn=1658-354X;year=2013;volume=7;issue=3;spage=283;epage=290;aulast=Singh;type=2




Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org

“Queremos una ley para realizar tamiz de cadera a niños”

“Queremos una ley para realizar tamiz de cadera a niños”

Publicada: 05:07 del 22/11/2013 -- Ciudad: Centro, Tabasco

(0)

“Queremos una ley para realizar tamiz de cadera a niños”

La doctora tabasqueña Sonia Castro lucha porque sea una obligación legal realizar pruebas para descartar displasia

La especialista en traumatología y ortopedia habló sobre sus proyectos en la SMOP.

- See more at: http://www.tabascohoy.com/2/notas/index.php?ID=161374#sthash.UYwJbgJV.dpuf

Por primera vez en 29 años de existencia, una mujer presidirá la Sociedad Mexicana de Ortopedia Pediátrica (SMOP), será la tabasqueña Sonia Castro Noriega, quien ha presentado una propuesta de ley ante el Congreso de la Unión para que por decreto a todos los niños recién nacidos y menores de cuatro meses, se les realice un radiografías para descartar la presencia de displasia de cadera.

La especialista en ortopedia y traumatología pediátrica, indicó que la luxación congénita de cadera o displasia del desarrollo de cadera, puede llegar a ser una enfermedad discapitante en la edad joven o adulta, de ahí su importancia para que se realicen las detecciones y correciones a temprana edad.

¿Cómo la nombran Presidenta de la Sociedad Mexicana de Ortopedia Pediátrica?

El año pasado me eligieron vicepresidenta y de acuerdo a los estatutos, este año rendiría protesta como presidenta, y así fue el pasado 17 de noviembre en nuestra asamblea anual, realizada en Campeche; a mí me proponen mis maestros y compañeros del hospital Shriners, donde hice mi especialidad.

¿Qué significado tiene esta distinción?

Para mí es de mucho orgullo, una porque soy la primer mujer que preside a la Sociedad, fui elegida entre 400 miembros, y otra porque soy tabasqueña y nos gusta que nos distingan a nivel nacional.

¿Qué la hace meritoria a este reconocimiento?

Aquí se valora o se evalúa el desempeño que cada uno de los agremiados de la SMOP ha tenido a lo largo de los años, el ejercicio a nivel hospitalario, las intervenciones que tenemos, la investigación, en los congresos, afortunadamente y gracias a la pasión que tengo por mi especialidad he tenido la oportunidad de participar en varios congresos nacionales e internacionales con ponencias, simposium y conferencias.

Además junto con cuatro colegas, elaboramos el plan nacional de detección oportuna de displasia del desarrollo de la cadera, conocido como luxación congénita de la cadera, que puede llegar a ser una enfermedad discapacitante; ya lo terminamos y posiblemente durante mi gestión nos toque ponerlo en marcha.

¿Ya lo han planteado a la Secretaría de Salud Pública o por donde empezarán?

Te adelantó que a nivel federal ante la Comision de Salud de la Cámara de Senadores, emitimos una propuesta para tratar que se genere una iniciativa de ley, por la que se estipule que todos los niños menores de 4 meses de edad se les haga una radiografía o un ultrasonido para estar seguros que no traen luxación de cadera o una displasia de cadera, porque desgraciadamente en nuestro país este padecimiento se detecta cuando el niño camina con dificultad, y está en trámite esta aprobación.

¿Cómo esta Tabasco en el tratamiento de displacia de cadera?

Desafortunadamente en México, no solo en Tabasco, no tenemos estadisticas de cuántas luxaciones de cadera por cada mil nacidos vivos, y eso es uno de los primeros trabajos que la Sociedad Mexicana de Ortopedia Pediatrica nos hemos propuesto, se van a empezar a realizar estudios, como una encuesta a nivel nacinal en cada Estado vamos a empezar a registrar el número de niños con displacia de cadera.

Yo en lo personal, en 16 años de estar trabajando en el hospital del niño como ortopedista, les puedo decir que si es un gran volumen de niños que nos ha tocado ver, y puedo asegurar que el 95 por ciento de las luxaciones de cadera se diagnosticaron a dis tiempo, es decir llegaron ya que el niño caminaba.

¿Porqué es importante que este plan se establezca en México?

Existe una asociación internacional ponseti, del manejo de estos piecitos que es con yesos, ya no con cirujias, se le va corrigiendo la deformidad sin someterlos a cirugias extensas.

La propuesta para implantar este Plan en México ya fue aceptada por la asociacion internacional Ponseti que esta en Iowa en Estados Unidos, revisó nuestro plan, lo acepto, le gustó y ya nos dio el aval y el reconocimiento para suplantación en el país, incluso lo estan tomando de modelo para implantarlo en Latinoamerica.

--- AMC - See more at: http://www.tabascohoy.com/2/notas/index.php?ID=161374#sthash.UYwJbgJV.dpuf

Levobupivacaína raquídea/Spinal levobupivacaine

Características clínicas de levobupivacaína espinal hiperbárica comparada con isobárica


Clinical characteristics of spinal levobupivacaine: hyperbaric compared with isobaric solution.
Sanansilp V, Trivate T, Chompubai P, Visalyaputra S, Suksopee P, Permpolprasert L, von Bormann B.
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
ScientificWorldJournal. 2012;2012:169076. doi: 10.1100/2012/169076. Epub 2012 Apr 24.
Abstract
We performed a prospective, double-blinded study in 20 patients undergoing gynecologic surgery with lower abdominal incision, to investigate characteristics of intrathecal hyperbaric levobupivacaine compared with isobaric levobupivacaine. We randomly assigned them to receive either isobaric or hyperbaric 0.42% levobupivacaine intrathecally. We found that hyperbaric levobupivacaine, compared with isobaric levobupivacaine, spread faster to T10 level (2.8 ± 1.1 versus 6.6 ± 4.7 minutes, P = 0.039), reached higher sensory block levels at 5 and 15 minutes after injection (T8 versus L1, P = 0.011, and T4 versus T7, P = 0.027, resp.), and had a higher peak level (T4 versus T8, P = 0.040). Isobaric levobupivacaine caused a wider range of peak levels (L1 to C8) compared with hyperbaric form (T7 to T2). The level of T4 or higher reached 90% in the hyperbaric group compared with 20% in the isobaric group (P = 0.005). Our results suggest that hyperbaric levobupivacaine was more predictable for sensory block level and more effective for surgical procedures with lower abdominal approach. Hyperbaric levobupivacaine seems to be suitable, but the optimal dosage needs further investigation.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349113/pdf/TSWJ2012-169076.pdf






Comparación entre levobupivacaína sola y en combinación con fentanilo y sufentanilo en pacientes para prostatectomía

Comparison of levobupivacaine alone and in combination with fentanyl and sufentanil in patients undergoing transurethral resection of the prostate.

Akan B, Yagan O, Bilal B, Erdem D, Gogus N.

Department of Anesthesia and Reanimation, Numune Training and Research Hospital, Ankara, Turkey.

J Res Med Sci. 2013 May;18(5):378-82.

Abstract

BACKGROUND:It was aimed to compare the efficacy and adverse effects of levobupivacaine alone and in combination with fentanyl and sufentanil during transurethral resection of the prostate (TURP) under spinal anesthesia.MATERIALS AND METHODS:In this prospective, randomized, double-blind trial, 60 patients undergoing elective TURP under spinal anesthesia were randomized into three groups. Ten milligrams of 0.5% levobupivacaine in Group-I, 7.5 mg 0.5% levobupivacaine combined with 25 μg fentanyl in Group-II and 7.5 mg 0.5% levobupivacaine with 2.5 μg sufentanil in Group-III were administered intrathecally. RESULTS: The time for sensorial block to reach level T10 was 10.2 ± 2.0, 6.9 ± 1.7 and 7.0 ± 1.4 min in Group-I, II and III, respectively (P < 0.001). The maximum sensorial block level was T8 in all groups. The frequency of a complete motor block was higher in Group-I. The mean duration of motor block was shorter in Group-II and III than in Group-I (P < 0.001). There were no differences between groups regarding side effects (P > 0.05). The time for first analgesic request was shorter in Group-I than in the other two groups (P < 0.05). During the first postoperative 24-h period, 11 (58%) patients in Group-I, 9 (48%) patients in Group II and 9 (45%) patients in Group-III required an analgesic drug (P > 0.05). CONCLUSION: This study showed that combining lower dose levobupivacaine with fentanyl and sufentanil provides faster onset of sensorial block, lower frequency and shorter duration of motor block, and longer analgesia time in TURP under spinal anesthesia.

KEYWORDS: Fentanyl, levobupivacaine, spinal anesthesia, sufentanil, transurethral resection of the prostate

http://journals.mui.ac.ir/jrms/article/view/9206/3898


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810569/



Influencia de la posición sobre levobupivacaína isobárica en anestesia espinal para cesárea
Influence of positioning on plain levobupivacaine spinal anesthesia in cesarean section.
Gori F, Corradetti F, Cerotto V, Peduto VA.
Section of Anesthesia and Intensive Care, University of Perugia, 06100 Perugia, Italy.
Anesthesiol Res Pract. 2010;2010. pii: 212696. doi: 10.1155/2010/212696. Epub 2010 May 24.
Abstract
Background. The behaviour of isobaric levobupivacaine in relation to gravity when used in obstetric spinal anesthesia is unclear. Methods. 46 women with ASA physical status 1 undergoing cesarean section were randomly allocated to 2 groups. Spinal anesthesia with 12.5 mg levobupivacaine was performed in the sitting position in all women. Those in the first group were placed in the supine position immediately after the injection, while those in the second group were asked to remain seated for 2 minutes before assuming the supine position. The sensory block level, the onset of sensory and motor blocks, the regression of the sensory block for 2 dermatomes of the sensory block, the first request for analgesics, and the regression of motor block were recorded. Results. No differences in onset times, sensory level, or Bromage score were observed between the two groups. The time of first analgesic request was earlier in the seated group (supine 131 +/- 42 min, seated 106 +/- 29 min, P = .02). Conclusion. Isobaric levobupivacaine in women at term produces a subarachnoid block the dermatomal level of which does not depend on gravitational forces.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911613/pdf/ARP2010-212696.pdf




Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org

21 de noviembre de 2013. A continuación le mostramos las novedades de las revistas más importantes en Condroprotección.

21 de noviembre de 2013



A continuación le mostramos las novedades de las revistas más importantes en Condroprotección.









Annals of the Rheumatic Diseases
November 2013, Volume 72, Issue 11

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative
Frank van den Hoogen, Dinesh Khanna, Jaap Fransen, Sindhu R Johnson, Murray Baron, Alan Tyndall, Marco Matucci-Cerinic, Raymond P Naden, Thomas A Medsger, Jr,Patricia E Carreira, Gabriela Riemekasten, Philip J Clements, Christopher P Denton,Oliver Distler, Yannick Allanore, Daniel E Furst, Armando Gabrielli, Maureen D Mayes,Jacob M van Laar, James R Seibold, Laszlo Czirjak, Virginia D Steen, Murat Inanc, Otylia Kowal-Bielecka, Ulf Müller-Ladner, Gabriele Valentini, Douglas J Veale, Madelon C Vonk,Ulrich A Walker, Lorinda Chung, David H Collier, Mary Ellen Csuka, Barri J Fessler,Serena Guiducci, Ariane Herrick, Vivien M Hsu, Sergio Jimenez, Bashar Kahaleh, Peter A Merkel, Stanislav Sierakowski, Richard M Silver, Robert W Simms, John Varga, Janet E Pope
Value of biomarkers in osteoarthritis: current status and perspectives
M Lotz, J Martel-Pelletier, C Christiansen, M-L Brandi, O Bruyère, R Chapurlat, J Collette,C Cooper, G Giacovelli, J A Kanis, M A Karsdal, V Kraus, W F Lems, I Meulenbelt, J-P Pelletier, J-P Raynauld, S Reiter-Niesert, R Rizzoli, L J Sandell, W E Van Spil, J-Y Reginster
Cardiovascular risk stratification in rheumatic diseases: carotid ultrasound is more sensitive than Coronary Artery Calcification Score to detect subclinical atherosclerosis in patients with rheumatoid arthritis
Alfonso Corrales, José A Parra, Carlos González-Juanatey, Javier Rueda-Gotor, Ricardo Blanco, Javier Llorca, Miguel A González-Gay
Results from systematic screening for cardiovascular risk in outpatients with rheumatoid arthritis in accordance with the EULAR recommendations
Jette Primdahl, Joan Clausen, Kim Hørslev-Petersen
Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study
Arthur Kavanaugh, Iain B McInnes, Philip J Mease, Gerald G Krueger, Dafna D Gladman,Désirée van der Heijde, Surekha Mudivarthy, Weichun Xu, Michael Mack, Zhenhua Xu,Anna Beutler
Hydroxychloroquine in systemic lupus erythematosus: results of a French multicentre controlled trial (PLUS Study)
Nathalie Costedoat-Chalumeau, Lionel Galicier, Olivier Aumaître, Camille Francès,Véronique Le Guern, Frédéric Lioté, Amar Smail, Nicolas Limal, Laurent Perard, Hélène Desmurs-Clavel, Du Le Thi Huong Boutin, Bouchra Asli, Jean-Emmanuel Kahn, Jacques Pourrat, Laurent Sailler, Félix Ackermann, Thomas Papo, Karim Sacré, Olivier Fain,Jerome Stirnemann, Patrice Cacoub, Moez Jallouli, Gaelle Leroux, Judith Cohen-Bittan,Marie-Laure Tanguy, Jean-Sébastien Hulot, Philippe Lechat, Lucile Musset, Zahir Amoura, Jean-Charles Piette, on behalf of Group PLUS
Efficacy and safety of adalimumab for the treatment of peripheral arthritis in spondyloarthritis patients without ankylosing spondylitis or psoriatic arthritis
Jacqueline E Paramarta, Leen De Rycke, Tanja F Heijda, Carmen A Ambarus, Koen Vos,Huib J Dinant, Paul P Tak, Dominique L Baeten
Construct and criterion validity of several proposed DAS28-based rheumatoid arthritis flare criteria: an OMERACT cohort validation study
Aatke van der Maas, Elisabeth Lie, Robin Christensen, Ernest Choy, Yaël A de Man, Piet van Riel, Thasia Woodworth, Alfons A den Broeder
Efficacy of biological agents in juvenile idiopathic arthritis: a systematic review using indirect comparisons
Marieke H Otten, Janneke Anink, Sandra Spronk, Lisette W A van Suijlekom-Smit
Heart failure risk among patients with rheumatoid arthritis starting a TNF antagonist
Daniel H Solomon, Jeremy A Rassen, Bindee Kuriya, Lang Chen, Leslie R Harrold,David J Graham, James D Lewis, Joyce Lii, Liyan Liu, Marie R Griffin, J R Curtis
Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis
Antonios Stavropoulos-Kalinoglou, Giorgos S Metsios, Jet JJCS Veldhuijzen van Zanten,Peter Nightingale, George D Kitas, Yiannis Koutedakis
Cardiovascular comorbidities antedating the diagnosis of rheumatoid arthritis
Anne M Kerola, Tuomas Kerola, Markku J Kauppi, Hannu Kautiainen, Lauri J Virta, Kari Puolakka, Tuomo V M Nieminen
Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial
Robert Zimmer, Hugo R Scherbarth, Oscar Luis Rillo, Juan Jesus Gomez-Reino,Sylviane Muller
Extent and distribution of CPP deposits in patients affected by calcium pyrophosphate dihydrate deposition disease: an ultrasonographic study
Georgios Filippou, Emilio Filippucci, Marika Tardella, Ilaria Bertoldi, Marco Di Carlo,Antonella Adinolfi, Walter Grassi, Bruno Frediani
Switching between TNF inhibitors in psoriatic arthritis: data from the NOR-DMARD study
Karen Minde Fagerli, Elisabeth Lie, Désirée van der Heijde, Marte Schrumpf Heiberg,Synøve Kalstad, Erik Rødevand, Knut Mikkelsen, Åse Stavland Lexberg, Tore K Kvien
Virtual skin biopsy by optical coherence tomography: the first quantitative imaging biomarker for scleroderma
Giuseppina Abignano, Sibel Zehra Aydin, Concepción Castillo-Gallego, Vasiliki Liakouli,Daniel Woods, Adam Meekings, Richard J Wakefield, Dennis G McGonagle, Paul Emery,Francesco Del Galdo
NKG2D stimulated T-cell autoreactivity in giant cell arteritis and polymyalgia rheumatica
Christian Dejaco, Christina Duftner, Juman Al-Massad, Annette D Wagner, Joon-Keun Park, Johannes Fessler, Ariane Aigelsreiter, Franz Hafner, Sandra Vega, William Sterlacci, Beatrix Grubeck-Loebenstein, Alexander Tzankov, Thomas Ness, Luigi Boiardi,Carlo Salvarani, Michael Schirmer
Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration
Kate Louise Eve Phillips, Nikki Jordan-Mahy, Martin J H Nicklin, Christine Lyn Le Maitre
Population-specific influence of SLC2A9 genotype on the acute hyperuricaemic response to a fructose load
Nicola Dalbeth, Meaghan E House, Gregory D Gamble, Anne Horne, Bregina Pool,Lauren Purvis, Angela Stewart, Marilyn Merriman, Murray Cadzow, Amanda Phipps-Green, Tony R Merriman
Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB
Svetlana Frank, Marvin A Peters, Corinna Wehmeyer, Simon Strietholt, Christina Koers-Wunrau, Jessica Bertrand, Marianne Heitzmann, Anja Hillmann, Joanna Sherwood,Christine Seyfert, Steffen Gay, Thomas Pap
Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis
A Serrano, A Márquez, S L Mackie, F D Carmona, R Solans, J A Miranda-Filloy, J Hernández-Rodríguez, M C Cid, S Castañeda, IC Morado, J Narváez, R Blanco, B Sopeña, M J García-Villanueva, J Monfort, N Ortego-Centeno, A Unzurrunzaga, B Marí-Alfonso, J Sánchez-Martín, E de Miguel, C Magro, E Raya, N Braun, J Latus, O Molberg, B A Lie, F Moosig, T Witte, A W Morgan, M A González-Gay, J Martín, UK GCA Consortium Spanish GCA Consortium







Arthritis & Rheumatism
Volume 65, Issue 11, November 2013

2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative
Frank van den Hoogen, Dinesh Khanna, Jaap Fransen, Sindhu R. Johnson, Murray Baron, Alan Tyndall, Marco Matucci-Cerinic, Raymond P. Naden, Thomas A. Medsger Jr., Patricia E. Carreira, Gabriela Riemekasten, Philip J. Clements, Christopher P. Denton, Oliver Distler, Yannick Allanore, Daniel E. Furst, Armando Gabrielli, Maureen D. Mayes, Jacob M. van Laar, James R. Seibold, Laszlo Czirjak, Virginia D. Steen, Murat Inanc, Otylia Kowal-Bielecka, Ulf Müller-Ladner, Gabriele Valentini, Douglas J. Veale, Madelon C. Vonk, Ulrich A. Walker, Lorinda Chung, David H. Collier, Mary Ellen Csuka, Barri J. Fessler, Serena Guiducci, Ariane Herrick, Vivien M. Hsu, Sergio Jimenez, Bashar Kahaleh, Peter A. Merkel, Stanislav Sierakowski, Richard M. Silver, Robert W. Simms, John Varga and Janet E. Pope
Association of Paraoxonase 1 Gene Polymorphism and Enzyme Activity With Carotid Plaque in Rheumatoid Arthritis
Christina Charles-Schoeman, Yuen Yin Lee, Ani Shahbazian, Alan H. Gorn, John FitzGerald, Veena K. Ranganath, Mihaela Taylor, Nagesh Ragavendra, Maureen McMahon, David Elashoff and Srinivasa T. Reddy
Familial Risks and Heritability of Rheumatoid Arthritis: Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age
Thomas Frisell, Marie Holmqvist, Henrik Källberg, Lars Klareskog, Lars Alfredsson and Johan Askling
Rituximab-Induced T Cell Depletion in Patients With Rheumatoid Arthritis: Association With Clinical Response
J. Mélet, D. Mulleman, P. Goupille, B. Ribourtout, H. Watier and G. Thibault
Methotrexate Normalizes Up-Regulated Folate Pathway Genes in Rheumatoid Arthritis
Marjolein Blits, Gerrit Jansen, Yehuda G. Assaraf, Mark A. van de Wiel, Willem F. Lems, Mike T. Nurmohamed, Dirkjan van Schaardenburg, Alexandre E. Voskuyl, Gert-Jan Wolbink, Saskia Vosslamber and Cornelis L. Verweij
Association of Low Baseline Levels of Erythrocyte Folate With Treatment Nonresponse at Three Months in Rheumatoid Arthritis Patients Receiving Methotrexate
M. C. F. J. de Rotte, P. H. P. de Jong, S. M. F. Pluijm, M. Bulatović Ćalasan, P. J. Barendregt, D. van Zeben, P. A. van der Lubbe, P. B. de Sonnaville, J. Lindemans, J. M. W. Hazes and R. de Jonge
Role of ADAM-17, p38 MAPK, Cathepsins, and the Proteasome Pathway in the Synthesis and Shedding of Fractalkine/CX3CL1 in Rheumatoid Arthritis
Brian A. Jones, Sharayah Riegsecker, Ayesha Rahman, Maria Beamer, Wissam Aboualaiwi, Sadik A. Khuder and Salahuddin Ahmed
ADAM15 Adds to Apoptosis Resistance of Synovial Fibroblasts by Modulating Focal Adhesion Kinase Signaling
Beate B. Böhm, Isabell Freund, Kristin Krause, Raimund W. Kinne and Harald Burkhardt
Lipopolysaccharide Increases the Incidence of Collagen-Induced Arthritis in Mice Through Induction of Protease HTRA-1 Expression
Yuzhu Hou, Haijiang Lin, Linnan Zhu, Zhaoting Liu, Fanlei Hu, Jianfeng Shi, Tao Yang, Xiaoyun Shi, Mingzhao Zhu, Bernard F. Godley, Qiang Wang, Zhanguo Li and Yong Zhao
Insufficient Autoantigen Presentation and Failure of Tolerance in a Mouse Model of Rheumatoid Arthritis
Jason Perera, Xiao Liu, Yuzhen Zhou, Nora E. Joseph, Liping Meng, Jerrold R. Turner and Haochu Huang
Periarticular Bone Loss in Antigen-Induced Arthritis
Cecilia Engdahl, Catharina Lindholm, Alexandra Stubelius, Claes Ohlsson, Hans Carlsten and Marie K. Lagerquist
ADAMTS-4_v1 Is a Splice Variant of ADAMTS-4 That Is Expressed as a Protein in Human Synovium and Cleaves Aggrecan at the Interglobular Domain
Shane D. Wainwright, Jan Bondeson, Bruce Caterson and Clare E. Hughes
Transplantation of Achilles Tendon Treated With Bone Morphogenetic Protein 7 Promotes Meniscus Regeneration in a Rat Model of Massive Meniscal Defect
Nobutake Ozeki, Takeshi Muneta, Hideyuki Koga, Hiroki Katagiri, Koji Otabe, Makiko Okuno, Kunikazu Tsuji, Eiji Kobayashi, Kenji Matsumoto, Hirohisa Saito, Tomoyuki Saito and Ichiro Sekiya
Headache in Systemic Lupus Erythematosus: Results From a Prospective, International Inception Cohort Study
John G. Hanly, Murray B. Urowitz, Aidan G. O’Keeffe, Caroline Gordon, Sang-Cheol Bae, Jorge Sanchez-Guerrero, Juanita Romero-Diaz, Ann E. Clarke, Sasha Bernatsky, Daniel J. Wallace, Ellen M. Ginzler, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Michelle Petri, Paul R. Fortin, Dafna D. Gladman, Barri J. Fessler, Graciela S. Alarcón, Ian N. Bruce, Mary Anne Dooley, Kristjan Steinsson, Munther A. Khamashta, Rosalind Ramsey-Goldman, Susan Manzi, Gunnar K. Sturfelt, Ola Nived, Asad A. Zoma, Ronald F. van Vollenhoven, Manuel Ramos-Casals, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Kenneth C. Kalunian, S. Sam Lim, Murat Inanc, Diane L. Kamen, Christine A. Peschken, Soren Jacobsen, Chris Theriault, Kara Thompson and Vernon Farewell
The Percentage of FoxP3+Helios+ Treg Cells Correlates Positively With Disease Activity in Systemic Lupus Erythematosus
Amit Golding, Sarfaraz Hasni, Gabor Illei and Ethan M. Shevach
Multiple Lupus-Associated ITGAM Variants Alter Mac-1 Functions on Neutrophils
Yebin Zhou, Jianming Wu, Dennis F. Kucik, Nathan B. White, David T. Redden, Alexander J. Szalai, Daniel C. Bullard and Jeffrey C. Edberg
Skin Gene Expression Correlates of Severity of Interstitial Lung Disease in Systemic Sclerosis
Shervin Assassi, Minghua Wu, Filemon K. Tan, Jeffrey Chang, Tiffany A. Graham, Daniel E. Furst, Dinesh Khanna, Julio Charles, Emma C. Ferguson, Carol Feghali-Bostwick and Maureen D. Mayes
Endothelial Injury in a Transforming Growth Factor β-Dependent Mouse Model of Scleroderma Induces Pulmonary Arterial Hypertension
Emma C. Derrett-Smith, Audrey Dooley, Adrian J. Gilbane, Sarah L. Trinder, Korsa Khan, Reshma Baliga, Alan M. Holmes, Adrian J. Hobbs, David Abraham and Christopher P. Denton
Fibrosis Caused by Loss of PTEN Expression in Mouse Fibroblasts Is Crucially Dependent on CCN2
Shangxi Liu, Sunil K. Parapuram and Andrew Leask
Clinically Significant Renal Involvement in Primary Sjögren’s Syndrome: Clinical Presentation and Outcome
Andreas V. Goules, Ioanna P. Tatouli, Haralampos M. Moutsopoulos and Athanasios G. Tzioufas
Most Patients With Cancer-Associated Dermatomyositis Have Antibodies to Nuclear Matrix Protein NXP-2 or Transcription Intermediary Factor 1γ
David F. Fiorentino, Lorinda S. Chung, Lisa Christopher-Stine, Lisa Zaba, Shufeng Li, Andrew L. Mammen, Antony Rosen and Livia Casciola-Rosen
Copy Number Variations of Complement Component C4 Are Associated With Behçet’s Disease but Not With Ankylosing Spondylitis Associated With Acute Anterior Uveitis
Shengping Hou, Jian Qi, Dan Liao, Qi Zhang, Jing Fang, Yan Zhou, Yunjia Liu, Lin Bai, Meifen Zhang, Aize Kijlstra and Peizeng Yang
Increased Intracellular Oxygen Radical Production in Neutrophils During Febrile Episodes of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome
Martina Sundqvist, Per Wekell, Veronica Osla, Johan Bylund, Karin Christenson, Karin Sävman, Dirk Foell, David A. Cabral, Anders Fasth, Stefan Berg, Kelly L. Brown and Anna Karlsson
Transient Receptor Potential Ankyrin 1 Receptor Stimulation by Hydrogen Peroxide Is Critical to Trigger Pain During Monosodium Urate-Induced Inflammation in Rodents
Gabriela Trevisan, Carin Hoffmeister, Mateus F. Rossato, Sara M. Oliveira, Mariane A. Silva, Rafael P. Ineu, Gustavo P. Guerra, Serena Materazzi, Camilla Fusi, Romina Nassini, Pierangelo Geppetti and Juliano Ferreira
Enhanced Activity of Akt in Teff Cells From Children With Lupus Nephritis Is Associated With Reduced Induction of Tumor Necrosis Factor Receptor-Associated Factor 6 and Increased OX40 Expression
Sudhir Kshirsagar, Elisabeth Binder, Magdalena Riedl, Gottfried Wechselberger, Elisabeth Steichen and Monika Edelbauer








The Journal of Rheumatology
November 2013; 40 (11)

Juvenile Versus Adult-onset Ankylosing Spondylitis - Clinical, Radiographic, and Social Outcomes. A Systematic Review
Deepak R. Jadon, Athimalaipet V. Ramanan, and Raj Sengupta
Inflammation and Hypertension in Rheumatoid Arthritis
Siriporn Manavathongchai, Aihua Bian, Young Hee Rho, Annette Oeser,Joseph F. Solus, Tebeb Gebretsadik, Ayumi Shintani, and C. Michael Stein
Comparison of the Disease Activity Score Using Erythrocyte Sedimentation Rate and C-reactive Protein in African Americans with Rheumatoid Arthritis
Ashutosh Tamhane, David T. Redden, Gerald McGwin, Jr., Elizabeth E. Brown, Andrew O. Westfall, Richard J. Reynolds IV, Laura B. Hughes, Doyt L. Conn, Leigh F. Callahan, Beth L. Jonas, Edwin A. Smith, Richard D. Brasington, Jr., Larry W. Moreland, and S. Louis Bridges, Jr.
Determining Best Practices in Early Rheumatoid Arthritis by Comparing Differences in Treatment at Sites in the Canadian Early Arthritis Cohort
Jamie A. Harris, Vivian P. Bykerk, Carol A. Hitchon, E.C. Keystone, J. Carter Thorne, Gilles Boire, Boulos Haraoui, Glen Hazlewood, Ashley J. Bonner,Janet E. Pope, Gilles Boire, Janet Pope, Boulos Haraoui, Carol Hitchon,Shahin Jamal, Carter Thorne, Dianne Mosher, Vandana Ahluwalia, William Bensen, Maggie Larché, Michel Zummer, Majed Khraishi, Bindu Nair, Alice Klinkhoff, Alf Cividino, and Vivian Bykerk
A Randomized Controlled Trial of an Internal Family Systems-based Psychotherapeutic Intervention on Outcomes in Rheumatoid Arthritis: A Proof-of-Concept Study
Nancy A. Shadick, Nancy F. Sowell, Michelle L. Frits, Suzanne M. Hoffman,Shelley A. Hartz, Fran D. Booth, Martha Sweezy, Patricia R. Rogers, Rina L. Dubin, Joan C. Atkinson, Amy L. Friedman, Fernando Augusto, Christine K. Iannaccone, Anne H. Fossel, Gillian Quinn, Jing Cui, Elena Losina, andRichard C. Schwartz
Increased Levels of Interleukin 34 in Serum and Synovial Fluid Are Associated with Rheumatoid Factor and Anticyclic Citrullinated Peptide Antibody Titers in Patients with Rheumatoid Arthritis
Su-Jin Moon, Yeon-Sik Hong, Ji Hyeon Ju, Seung-Ki Kwok, Sung-Hwan Park, and Jun-Ki Min
Orthopedic Surgery in Rheumatoid Arthritis in the Era of Biologic Therapy
Leticia Leon, Lydia Abasolo, Loreto Carmona, Luis Rodriguez-Rodriguez,Jose Ramon Lamas, Cesar Hernandez-Garcia, Juan Angel Jover, for the emAR Study Group, J Alegre, JL Alonso, M Alvarez, B Alvárez, A Aragón, FX Arasa, MJ Arias, J Beltrán, J Babío, C Bohorquez, D Boquet, S Bustabad, A Casado, J Calvet, S Castro, MR Colazo, E Collantes, E Cuende, N Chozas, E Delgado, D de la Fuente, A de Juanes, E del Rincón, E Enríquez, C Escudero,L Espadaler, P Espino, A Fernández, J Fernández, L Fernández, J Fiter, P Font, J Galvez, A Gallego, J García, J García, ME García, F Gamero, E Giménez, S Gómez, B González Álvarez, S González, M Granados, G Iglesias,V Irigoyen, F Jimenez, E Júdez, C López, M López, R López, FJ López-Longo,J Maese, FJ Manero-Ruiz, S Manrique, I Maries, C Martínez, A Martínez-Cristóbal, I Mateo, J Marzo, F Medina, J Medina, M Medrano, P Mesa, R Miguélez, I Monteagudo, C Montilla, I Moreno, ML Muñoz, A Naranjo, R Negueroles, M Nolla, S Ojeda, C Ordás, S Ordóñez, AM Ortíz, E Pagán, A Pecondón, S Esteban, E Pérez-Pampín, JM Pina, JA Piqueras, MJ Pozuelo, V Rios, N Rivera, C Rodríguez, JM Rodríguez, R Roselló, MJ Rubira, D Ruiz, E Saiz, M Sánchez, T Tinturé, C Tornero, J Tornero, E Úcar, I Ureña, C Vázquez, R Veroz, E Vicente, and J Zubieta
Low Levels of Antibodies Against Oxidized but not Nonoxidized Cardiolipin and Phosphatidylserine Are Associated with Atherosclerotic Plaques in Systemic Lupus Erythematosus
Jun Su, Anna G. Frostegård, Xiang Hua, Thomas Gustafsson, Tomas Jogestrand, Ingiäld Hafström, and Johan Frostegård
Impaired Health Status and the Effect of Pain and Fatigue on Functioning in Clinical Trial Patients with Systemic Lupus Erythematosus
Michelle Petri, Ariane K. Kawata, Ancilla W. Fernandes, Kavita Gajria, Warren Greth, Asha Hareendran, and Dominique Ethgen
Herpes Zoster Vaccination in SLE: A Pilot Study of Immunogenicity
Joel M. Guthridge, Abigail Cogman, Joan T. Merrill, Susan Macwana, Krista M. Bean, Tiny Powe, Virginia Roberts, Judith A. James, and Eliza F. Chakravarty
Low Bone Density in Systemic Sclerosis. A Systematic Review
Mohammed A. Omair, Christian Pagnoux, Heather McDonald-Blumer, andSindhu R. Johnson
Vertebral Erosions Associated with Spinal Inflammation in Patients with Ankylosing Spondylitis Identified by Magnetic Resonance Imaging: Changes After 2 Years of Tumor Necrosis Factor Inhibitor Therapy
Xenofon Baraliakos, Joachim Listing, Hildrun Haibel, Joachim Sieper, andJurgen Braun
High Prevalence of Metabolic Syndrome in Takayasu Arteritis: Increased Cardiovascular Risk and Lower Adiponectin Serum Levels
Thiago Ferreira da Silva, Maurício Levy-Neto, Eloisa Bonfá, and Rosa Maria R. Pereira
New Features of Disease After Diagnosis in 6 Forms of Systemic Vasculitis
Peter C. Grayson, David Cuthbertson, Simon Carette, Gary S. Hoffman,Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Kathleen Maksimowicz-McKinnon, Paul A. Monach, Philip Seo, Ulrich Specks, Steven R. Ytterberg, Peter A. Merkel, and for the Vasculitis Clinical Research Consortium
Aberrant CpG Islands' Hypermethylation of ABCB1 in Mesenchymal Stem Cells of Patients with Steroid-associated Osteonecrosis
Zhibo Sun, Shuhua Yang, Shunan Ye, Yukun Zhang, Weihua Xu, Bo Zhang,Xianzhe Liu, Fengbo Mo, and Wenbin Hua







Osteoarthritis and Cartilage
Volume 21, Issue 11, Pages 1627-1812 (November 2013)

Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review
Y. Zhu, M. Yuan, H.Y. Meng, A.Y. Wang, Q.Y. Guo, Y. Wang, J. Peng
Articular osteochondrosis: a comparison of naturally-occurring human and animal disease
A.M. McCoy, F. Toth, N.I. Dolvik, S. Ekman, J. Ellermann, K. Olstad, B. Ytrehus, C.S. Carlson
What proportion of people with hip and knee osteoarthritis meet physical activity guidelines? A systematic review and meta-analysis
J.A. Wallis, K.E. Webster, P. Levinger, N.F. Taylor
Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis
K. Wiegant, P.M. van Roermund, F. Intema, S. Cotofana, F. Eckstein, S.C. Mastbergen, F.P.J.G. Lafeber
Varus thrust and knee frontal plane dynamic motion in persons with knee osteoarthritis
A.H. Chang, J.S. Chmiel, K.C. Moisio, O. Almagor, Y. Zhang, S. Cahue, L. Sharma
Subsets of symptomatic hand osteoarthritis in community-dwelling older adults in the United Kingdom: prevalence, inter-relationships, risk factor profiles and clinical characteristics at baseline and 3-years
M. Marshall, G. Peat, E. Nicholls, D. van der Windt, H. Myers, K. Dziedzic
Association of cartilage defects, and other MRI findings with pain and function in individuals with mild-moderate radiographic hip osteoarthritis and controls
D. Kumar, C.R. Wyatt, S. Lee, L. Nardo, T.M. Link, S. Majumdar, R.B. Souza
High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment
V.B. Kraus, T.W. Worrell, J.B. Renner, R.E. Coleman, C.F. Pieper
Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis
D. Xing, X.-L. Ma, J.-X. Ma, W.-G. Xu, J. Wang, Y. Yang, Y. Chen, B.-Y. Ma, S.-W. Zhu
Differential accumulation of lead and zinc in double-tidemarks of articular cartilage
A. Roschger, J.G. Hofstaetter, B. Pemmer, N. Zoeger, P. Wobrauschek, G. Falkenberg, R. Simon, A. Berzlanovich, H.W. Thaler, P. Roschger, K. Klaushofer, C. Streli
Bone loss at subchondral plate in knee osteoarthritis patients with hypertension and type 2 diabetes mellitus
C.Y. Wen, Y. Chen, H.L. Tang, C.H. Yan, W.W. Lu, K.Y. Chiu
Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis
D. Bobinac, M. Marinovic, E. Bazdulj, O. Cvijanovic, T. Celic, I. Maric, J. Spanjol, T. Cicvaric
Electroarthrography: a novel method to assess articular cartilage and diagnose osteoarthritis by non-invasive measurement of load-induced electrical potentials at the surface of the knee
A.-M. Préville, P. Lavigne, M.D. Buschmann, J. Hardin, Q. Han, L. Djerroud, P. Savard
Estrogen reduces mechanical injury-related cell death and proteoglycan degradation in mature articular cartilage independent of the presence of the superficial zone tissue
J. Imgenberg, B. Rolauffs, A.J. Grodzinsky, M. Schünke, B. Kurz
Demineralized bone matrix and platelet-rich plasma do not improve healing of osteochondral defects of the talus: an experimental goat study
C.J.A. van Bergen, G.M.M.J. Kerkhoffs, M. Özdemir, C.M. Korstjens, V. Everts, L.J. van Ruijven, C.N. van Dijk, L. Blankevoort
Rapid in situ chondrocyte death induced by Staphylococcus aureus toxins in a bovine cartilage explant model of septic arthritis
I.D.M. Smith, J.P. Winstanley, K.M. Milto, C.J. Doherty, E. Czarniak, S.G.B. Amyes, A.H.R.W. Simpson, A.C. Hall
Interleukin 6 mediates selected effects of Notch in chondrocytes
S. Zanotti, E. Canalis
Synovial fluid levels of bradykinin correlate with biochemical markers for cartilage degradation and inflammation in knee osteoarthritis
F. Bellucci, S. Meini, P. Cucchi, C. Catalani, A. Nizzardo, A. Riva, G.M. Guidelli, P. Ferrata, A. Fioravanti, C.A. Maggi
Oxidative stress and status of antioxidant enzymes in children with Kashin-Beck disease
W. Wang, S. Wei, M. Luo, B. Yu, J. Cao, Z. Yang, Z. Wang, M.B. Goldring, J. Chen
Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system
J.A. Collins, R.J. Moots, R. Winstanley, P.D. Clegg, P.I. Milner
Monitoring wound healing of elastic cartilage using multiphoton microscopy
X. Zhu, Y. Tang, J. Chen, S. Xiong, S. Zhuo, J. Chen
Targeting of ADAMTS5’s ancillary domain with the recombinant mAb CRB0017 ameliorates disease progression in a spontaneous murine model of osteoarthritis
R. Chiusaroli, M. Visentini, C. Galimberti, C. Casseler, L. Mennuni, S. Covaceuszach, M. Lanza, G. Ugolini, G. Caselli, L.C. Rovati, M. Visintin







The Journal of Bone and Joint Surgery
November 06, 2013 | Vol. 95. Issue 21

Management of the Pediatric Pulseless Supracondylar Humeral Fracture: Is Vascular Exploration Necessary?
Amanda Weller, MD; Sumeet Garg, MD; A. Noelle Larson, MD; Nicholas D. Fletcher, MD; Jonathan R. Schiller, MD; Michael Kwon, MD; Lawson A.B. Copley, MD; Richard Browne, PhD; Christine A. Ho, MD
The Perfused, Pulseless Supracondylar Humeral Fracture: Intermediate-Term Follow-up of Vascular Status and Function
Brian P. Scannell, MD; J. Benjamin Jackson, III, MD; Christopher Bray, MD; Timothy S. Roush, MD; Brian K. Brighton, MD; Steven L. Frick, MD
Latissimus Dorsi Tendon Transfer for Treatment of Irreparable Posterosuperior Rotator Cuff Tears: Long-Term Results at a Minimum Follow-up of Ten Years
Christian Gerber, MD, FRCSEd(Hon); Stefan A. Rahm, MD; Sabrina Catanzaro, MD; Mazda Farshad, MD, MPH; Beat K. Moor, MD
Differences in Outcomes Following Total Ankle Replacement in Patients with Neutral Alignment Compared with Tibiotalar Joint Malalignment
Robin M. Queen, PhD; Samuel B. Adams, Jr., MD; Nicholas A. Viens, MD; Jennifer K. Friend, AS; Mark E. Easley, MD; James K. DeOrio, MD; James A. Nunley, MD
Local Infiltration Analgesia Followed by Continuous Infusion of Local Anesthetic Solution for Total Hip Arthroplasty: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Olga Solovyova, MD; Courtland G. Lewis, MD; Jonathan H. Abrams, MD; John Grady-Benson, MD; Michael E. Joyce, MD; Steven F. Schutzer, MD; Sivasenthil Arumugam, MBBS; Stephanie Caminiti, APRN; Sanjay K. Sinha, MBBS
One-to-One Therapy Is Not Superior to Group or Home-Based Therapy After Total Knee Arthroplasty: A Randomized, Superiority Trial
Victoria Ko, BAppSc; Justine Naylor, PhD; Ian Harris, PhD; Jack Crosbie, PhD; Anthony Yeo, PhD; Rajat Mittal, BSc, MBBS, MMed(ClinEpi)
Return of Motor Function After Repair of a 3-cm Gap in a Rabbit Peroneal Nerve: A Comparison of Autograft, Collagen Conduit, and Conduit Filled with Collagen-GAG Matrix
Tatevik Sahakyants, MD; Joo-Yup Lee, MD, PhD; Patricia F. Friedrich, AAS; Allen T. Bishop, MD; Alexander Y. Shin, MD
Topical (Intra-Articular) Tranexamic Acid Reduces Blood Loss and Transfusion Rates Following Total Knee Replacement: A Randomized Controlled Trial (TRANX-K)
Sattar Alshryda, MBChB, MRCS, MRCSEd, FRCS(Tr&Orth), PhD; James Mason, DPhil, MSc, BSc(Hons); Manesh Vaghela, MBBS, MS, MSc; Praveen Sarda, MBBS, MRCS, FRCS(Tr&Orth); Antoni Nargol, MBBS, FRCS, FRCS(Tr&Orth); S. Maheswaran, MBBS, FRCS; Chris Tulloch, FRCS; Sanjeev Anand, MBBS, FRCSI, FRCS(Tr&Orth), MFSEM; Raj Logishetty, MBBS, FRCS, FRCS(Tr&Orth); Brian Stothart, NMC(ENB), NCFE; A. Pali S. Hungin, MD, FRCGP, FRCP, FRSA
The Value of Intraoperative Histology in Predicting Infection in Patients Undergoing Revision Elbow Arthroplasty
Shahryar Ahmadi, MD; Thomas M. Lawrence, MBChB; Bernard F. Morrey, MD; Joaquin Sanchez-Sotelo, MD
Comparison of Distal Soft-Tissue Procedures Combined with a Distal Chevron Osteotomy for Moderate to Severe Hallux Valgus: First Web-Space Versus Transarticular Approach
Yu-Bok Park, MD; Keun-Bae Lee, MD, PhD; Sung-Kyu Kim, MD; Jong-Keun Seon, MD, PhD; Jun-Young Lee, MD, PhD
Mid-Term Outcome After Curettage with Polymethylmethacrylate for Giant Cell Tumor Around the Knee: Higher Risk of Radiographic Osteoarthritis?
Lizz Van Der Heijden, MSc; Michiel A.J. Van De Sande, MD, PhD; Adriaan C. Heineken; Marta Fiocco, PhD; Rob G.H.H. Nelissen, MD, PhD; P.D. Sander Dijkstra, MD, PhD
Functional Outcomes After Total Shoulder Arthroplasty in Obese Patients
Xinning Li, MD; Phillip N. Williams, MD; Joseph T. Nguyen, MPH; Edward V. Craig, MD, MPH; Russell F. Warren, MD; Lawrence V. Gulotta, MD
Mechanisms and Risk Factors o

	f Brachial Plexus Injury in the Treatment of Early-Onset Scoliosis with Distraction-Based Growing Implants Elizabeth R.A. Joiner, BS; Lindsay M. Andras, MD; David L. Skaggs, MD, MMM   Complications, Reoperation Rates, and Health-Care Cost Following Surgical Treatment of Lumbar Spondylolisthesis Shivanand P. Lad, MD, PhD; Ranjith Babu, MS; Abdul A. Baker, MD; Beatrice Ugiliweneza, PhD, MSPH; Maiying Kong, PhD; Carlos A. Bagley, MD; Oren N. Gottfried, MD; Robert E. Isaacs, MD; Chirag G. Patil, MD; Maxwell Boakye, MD, MPH   Histologic, Serologic, and Tribologic Findings in Failed Metal-on-Metal Total Hip Arthroplasty: AAOS Exhibit Selection Christopher E. Pelt, MD; Jill Erickson, PA-C; Ian Clarke, PhD; Thomas Donaldson, MD; Lester Layfield, MD; Christopher L. Peters, MD   Use of Porous Tantalum for Acetabular Reconstruction in Revision Hip Arthroplasty Paul S. Issack, MD, PhD   Journal of the American Academy of Orthopaedic Surgeons November 2013; 21 (11)  Management of Septic Arthritis Following Anterior Cruciate Ligament Reconstruction: A Review of Current Practices and Recommendations Edwin R. Cadet, Eric C. Makhni, Nima Mehran, and Brian M. Schulz   Foot Compartment Syndrome: Diagnosis and Management Andrew Dodd and Ian Le   Hip Pathology in the Adolescent Athlete Jeremy S. Frank, Peter L. Gambacorta, and Eric A. Eisner   Tendon Transfers for Radial, Median, and Ulnar Nerve Palsy John G. Seiler III, Mihir J. Desai, and S. Houston Payne   Management of Metastatic Bone Disease of the Acetabulum Paul S. Issack, Suhel Y. Kotwal, and Joseph M. Lane   Driving After Orthopaedic Surgery Geoffrey S. Marecek and Michael F. Schafer