jueves, 10 de mayo de 2012

Obesidad y embarazo


Efecto del IMC materno sobre la evolución del embarazo y del recién nacido 
Effect of maternal body mass index on pregnancy outcome and newborn weight.
Yazdani S, Yosofniyapasha Y, Nasab BH, Mojaveri MH, Bouzari Z.
Department of Anesthesia, Babol University of Medical Sciences, Babol, Iran. bahmanh2002@yahoo.com.
BMC Res Notes. 2012 Jan 17;5:34.
Abstract
BACKGROUND: Maternal obesity has been associated with adverse pregnancy outcomes, such as pre-eclampsia, eclampsia, pre- and post-term delivery, induction of labor, macrosomia, increased rate of caesarean section, and post-partum hemorrhage. The objective of this study was to determine the effect of maternal Body Mass Index (BMI) on pregnancy outcomes. METHODS: 1000 pregnant women were enrolled in the study. In order to explore the relationship between maternal first trimester Body Mass Index and pregnancy outcomes, participants were categorized into five groups based on their first trimester Body Mass Index. The data were analyzed using Pearson Chi-square tests in SPSS 18. Differences were considered significant if p < 0.05. RESULTS: Women with an above-normal Body Mass Index had a higher incidence of pre-eclampsia, induction of labor, caesarean section, pre-term labor, and macrosomia than women with a normal Body Mass Index (controls). There was no significant difference in the incidence of post-term delivery between the control group and other groups. CONCLUSION: Increased BMI increases the incidence of induction of labor, caesarean section, pre-term labor and macrosomia. The BMI of women in the first trimester of pregnancy is associated with the risk of adverse pregnancy outcome.
http://www.biomedcentral.com/content/pdf/1756-0500-5-34.pdf 
DE(50) y DE(95) de bupivacaína intratecal en obesas mórbidas sometidas a parto por cesárea
ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery.
Carvalho B, Collins J, Drover DR, Atkinson Ralls L, Riley ET.
Department of Anesthesia, Stanford University School of Medicine, Stanford, California 94305, USA. bcarvalho@stanford.edu
Anesthesiology. 2011 Mar;114(3):529-35.
Abstract
BACKGROUND: It has been suggested that morbidly obese parturients may require less local anesthetic for spinal anesthesia. The aim of this study was to determine the effective dose (ED(50)/ED(95)) of intrathecal bupivacaine for cesarean delivery in morbidly obese patients. METHODS: Morbidly obese parturients (body mass index equal to or more than 40) undergoing elective cesarean delivery were enrolled in this double-blinded study. Forty-two patients were randomly assigned to receive intrathecal hyperbaric bupivacaine in doses of 5, 6, 7, 8, 9, 10, or 11 mg (n = 6 per group) coadministered with 200 μg morphine and 10 μg fentanyl. Success (induction) was defined as block height to pinprick equal to or more than T6 and success (operation) as success (induction) plus no requirement for epidural supplementation throughout surgery. The ED(50)/ED(95) values were determined using a logistic regression model. RESULTS: ED(50) and ED(95) (with 95% confidence intervals) for success (operation) were 9.8 (8.6-11.0) and 15.0 (10.0-20.0), respectively, and were similar to corresponding values of a nonobese population determined previously using similar methodology. We were unable to measure ED(50)/ED(95) values for success (induction) because so few blocks failed initially, even at the low-dose range. There were no differences with regard to secondary outcomes (i.e., hypotension, vasopressor use, nausea, and vomiting). CONCLUSIONS: Obese and nonobese patients undergoing cesarean delivery do not appear to respond differently to modest doses of intrathecal bupivacaine. This dose-response study suggests that doses of intrathecal bupivacaine less than 10 mg may not adequately ensure successful intraoperative anesthesia. Even when the initial block obtained with a low dose is satisfactory, it will not guarantee adequate anesthesia throughout surgery.
http://journals.lww.com/anesthesiology/pages/articleviewer.aspx?year=2011&issue=03000&article=00016&type=abstract 
Imagen y obesidad: una perspectiva durante el embarazo 
Imaging and obesity: a perspective during pregnancy.
Maxwell C, Glanc P.
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Mount Sinai Hospital, Toronto, ON, Canada.
AJR Am J Roentgenol. 2011 Feb;196(2):311-9.
Abstract
OBJECTIVE: Obesity is a rapidly growing global pandemic that has surpassed all other risk factors in obstetric care, converting 40% of pregnant women into a high-risk category, with the attendant increased burden on our health care systems. This article will review the role of the imaging specialist in understanding the determinants of poor pregnancy outcome in the mother and her baby. We will also review how obesity affects the quality of patient care in terms of the limitation in completion of fetal anatomic surveys, ergonomic risks to the imaging specialist, and techniques that may improve imaging quality and ensure patient safety. We urgently need refinement in our ability to detect those fetuses at greatest risk for stillbirth and growth restriction, macrosomia, and congenital anomalies, and to understand the potentially multigenerational impact of maternal obesity on the incidence of obesity and the metabolic syndrome for the future. Utilization of emerging technologies such as laser Doppler, evolving MRI technology, and expanded roles for ultrasound such as ultrasound guidance for placement of labor anesthesia will become increasingly important. CONCLUSION: The far-reaching implications of obesity on the mother and her children will continue have a progressive impact on our health care systems and resources.
http://www.ajronline.org/content/196/2/311.full.pdf 
Atentamente
Anestesiología y Medicina del Dolor

Enterocolitis Necrosante actualización 2012


Estimado Pediatra  te invito al Seminario de Pediatría, 

Cirugía Pediátrica y Lactancia Materna. Programa 2012, el 

día 16 de mayo  las 21hrs (Centro, México DF, Guadalajara 

y Lima Perú) a la Conferencia:

“Enterocolitis Necrosante actualización 2012”  por  el  “Dr. Guillermo Gutiérrez Calleros ” Pediatra Neonatólogo de la Cd de Phoenix Ar.   

La sesión inicia puntualmente las 21 hrs. 
Para entrar a la Sala de Conferencia:
1.- hacer click en la siguiente liga, o cópiala y escríbela en tu buscador


2.- “Entra como Invitado” Escribes tu nombre y apellido en el espacio en blanco 
3.- Hacer click en el espacio que dice “Entrar en la Sala”
5.- A disfrutar la conferencia                                                                                                                            

6.- Recomendamos que dejes tu Nombre Completo, Correo electrónico y que participes.

Henrys
 
Dr. Enrique Mendoza López
Webmaster: CONAPEME
Coordinador Nacional: Seminario Ciberpeds-Conapeme
Av La clinica 2520-310 
Colonia Sertoma ,Mty N.L. México
CP 64710
Tel-Fax 52 81 83482940 y 52 81 81146053
Celular 8183094806
www.conapeme.org
www.pediatramendoza.com
enrique@pediatramendoza.com
emendozal@yahoo.com.mx

New Cautions About Long-Term Use of Bone Drugs


http://well.blogs.nytimes.com/2012/05/09/new-cautions-about-long-term-use-of-bone-drugs/?src=me&ref=general


New Cautions About Long-Term Use of Bone Drugs

WELL WOMAN |   | May 9, 2012, 6:32 PM 80 Comments
An X-ray shows a fracture in the femur of a woman who used Fosamax for seven years.An X-ray shows a fracture in the femur of a woman who used Fosamax for seven years.

The F.D.A. review
, published in The New England Journal of Medicine online on Wednesday, was prompted by a growing debate over how long women should continue using the drugs, known as bisphosphonates, which are sold as generic versions of brands like Fosamax and Boniva, as well as Novartis’s Reclast.In an unusual move that may prompt millions of women to rethink their use of popular bone-building drugs, the Food and Drug Administration published an analysis that suggested caution about long-term use of the drugs, but fell short of issuing specific recommendations.
The concern is that after years of use, the drugs may in rare cases actually lead to weaker bones in certain women, contributing to “rare but serious adverse events,” including unusual femur fractures, esophageal cancer and osteonecrosis of the jaw, a painful and disfiguring crumbling of the jaw bone.
Although the concerns about the long-term safety of bone drugs are not new, the F.D.A. performed its own systematic review of the effectiveness of bisphosphonates after years of use. The agency’s analysis, which found little if any benefit from the drugs after three to five years of use, may prompt doctors around the country to rethink how they prescribe them.
The F.D.A. review analyzes only long-term use and does not address whether a woman should be prescribed a bone drug in the first place to reduce her fracture risk. Because serious complications are so rare, most doctors believe that for women with documented osteoporosis who are at very high risk for spinal fractures, the benefits of the drugs far outweigh the risks. However, some women with moderate bone density and no other risk factors continue to take the drugs for years even though they are unlikely to gain any benefits.
“I think a lot of people are going to come off this drug,” said Dr. Clifford J. Rosen, an endocrinologist and researcher at the Maine Medical Center Research Institute.
Bones are in a constant state of remodeling, but after age 30 or so, a woman’s bones start to dissolve faster than they can be rebuilt, and after menopause she may develop thin, brittle bones that are easily broken. Bisphosphonates slow this process. The drugs are incorporated into newly formed bone and can persist there for years, long after a patient stops taking them.
The F.D.A. report offered little specific guidance about long-term use, saying that the decision to continue or stop treatment should be based on an individual assessment of risks, benefits and preferences discussed between a patient and her doctor. The agency did say that women at low risk for fracture or with a bone density near normal may be good candidates to stop therapy after three to five years, but older patients at higher fracture risk and bone density “in the osteoporotic range” may benefit from continued therapy.
But an accompanying article by Dr. Rosen and others, also published in The New England Journal of Medicine, offers more specifics, concluding that the women most likely to benefit from long-term use of the drugs are those who, after three to five years of treatment, continue to have very low bone density, as measured by something called a “T score” that is lower than minus 2.5. Women with a history of spinal fracture or with an existing fracture also are most likely to benefit from long-term use of the drugs, the researchers concluded.
However, many women who are prescribed bone drugs have been given a diagnosis of osteopenia, moderate to low bone density that is not low enough to be called osteoporosis. These women are unlikely to benefit from long-term use and should probably stop taking the drugs after about three years, the researchers said.
It is not clear how many women would be affected based on those recommendations, but many women tire of the therapy and stop taking it on their own anyway, partly because of inconvenient requirements like remaining upright after taking the drugs and common side effects of heartburn, nausea and flulike symptoms. Even so, the researchers estimate that perhaps 60 percent to 70 percent of current users would be candidates for stopping the drugs after three to five years.
The recommendations are based on findings from two industry-sponsored studies led by the University of California, San Francisco, that focused on long-term use of the drugs. A study of Fosamax, which is sold generically as alendronate, continued for 10 years, and a study of Reclast, an injectable form of the drug zoledronic acid, continued for six years. According to the F.D.A. analysis, both studies showed significant reductions in fracture risks during the first three to four years of use but little or no benefit with longer use.
In the Fosamax trial, 10.6 percent of Fosamax users suffered a fracture during the first three years of use, compared with 21 percent of those in the placebo group, according to the F.D.A. analysis. But there was no benefit seen among women who continued the drug for the next 5 to 10 years. In the Reclast trial, 9.8 percent of women taking the drug suffered a fracture in the first three years of the study, compared with 20 percent of women who were taking a placebo. By four to six years, the benefit had narrowed, with 8.6 percent of Reclast users suffering fractures, compared with 12 percent in the placebo group.
The two studies did not show any increased risk of serious side effects with long-term use of bisphosphonates, but experts say the studies simply were not large enough to detect a relatively rare adverse event. Even so, there have been numerous case reports of the unusual fractures and other side effects, prompting widespread concern about the risks with long-term use. No one knows how common the femur fractures are, but estimates have ranged from 1 in 10,000 users to 10 in 10,000.
Women should be reassured that serious complications are rare, saidDennis M. Black, a professor of epidemiology and biostatistics at U.C.S.F. and the lead author of the article that accompanied the F.D.A. report.
“The reality is there is a lot of uncertainty in this situation,” Dr. Black said. “The F.D.A. report was very general, and we tried to be much more specific and use evidence from the best trial available. Hopefully people who are using this drug will be reassured.”
Dr. Rosen said that even though the F.D.A. report was vague on specific recommendations, he was pleased to see the analysis published.
“It’s a very new thing that they submit a paper to The New England Journal that presents all sides of the argument,” Dr. Rosen said. “I think it’s a good thing, because I’ve been on these advisory committees for years, and we get a big crowd in Washington, but the doctors never see the results.”

Epifisiolistesis parte 2

Epifisiolistesis parte 1

Plática impartida por el Dr. Silvestre Fuentes Figueroa, médico adscrito al Servicio de Ortopedia Pediátrica del Hospital de Ortopedia Dr. Victorio de la Fuente Narváez, IMSS cd. de México Distrito Federal, el 09 de mayo 2012.
http://youtu.be/diPjcpiWCQk

miércoles, 9 de mayo de 2012

CMO. Cursos de práctica quirúrgica en espécimen biológico





CMO. Cursos de práctica quirúrgica en espécimen biológico

Fechas:

15 y 16 de junio - Hombro - profesor titular Dr M. Iván Encalada 
Días

30 y 31 de agosto - Rodilla - profesor titular Dr Francisco Javier
Lozano Pardinas

5 y 6 de octubre - Muñeca y codo - profesor titular Dr Alejandro de
Jesus Espinosa
Gutiérrez

16 y 17 de noviembre - Cadera - profesor titular Dr Víctor Ilizaliturri
Sanchez

Costo:
Médico ortopedista y/ residentes : $ 3,500.00 mn

Cupo: limitado a doce asistentes por curso.

Sede:
UNAM, facultad de médicina
Centro de enseñanza y adiestramiento quirúrgico
Torre de ivestigación, 4 piso.

Requisitos:

Cédula profesional de especialista

Coordinador: Dr Jorge Negrete Corona

Dirigido a : Residentes y médicos en traumatología y ortopedia.

Horario: 8-14 hrs.

Informes e inscripciones: Colegio Mexicano de Ortopedia y traumatología AC, WTC México, Montecito # 38, piso 25
oficinas 23-27 col Nápoles, cp 03810, México D.F.
tels 55-9000-2790 al 94
eventos@smo.edu.mx, smo@smo.edu.mx / www.smo.edu.mx

Para facilitar su inscripción, le solicitamos haga su deposito referenciado en el banco BBVA Bancomer a la cuenta 0448759111
a nombre de: Colegio Mexicano de Ortopedia y Traumatología, A.C.
Transferencia interbancaria con clabe 012180004487591114

CMO. Ortopedistas. Cursos en el servicio médico forense de la ciudad de México





Ortopedistas. Cursos en el servicio médico forense de la ciudad de México.
Fechas: 
26 y 27 de julio de 2012.
Disección anatómica de la extremidad torácica y pélvica.
1 er día: Anatomía topográfica disección.
2 do día: abordajes quirúrgicos- Anatomía quirúrgica.
Miembro inferior cadera, rodilla y tobillo) .

25 y 26 de octubre de 2012.
Técnicas quirúrgicas: miembro superior (hombro, codo y muñeca).

Coordinadores:
Dr. Arturo Gutiérrez Meneses
Dr. Antonio Maldonado y Tapia

Costo:
Médico ortopedista no miembro CMO $ 2,500.00 mn
Médico ortopedista miembro CMO $ 1,500.00 mn
Médico residente $ 1,000.00 mn

Cupo limitado a 10 asistentes.

Sede: SEMEFO
Av. Niños Heroes # 130, esquina dr Liceaga, col doctores
CP 06720 delegación Cuauhtémoc.

Informes e inscripciones: Colegio Mexicano de Ortopedia y traumatología A.C. WTC México, montecito 38. piso 25 oficinas 23-27. tel 55-9000-2790 al 94 ext 113 eventos@smo.edu.mx

martes, 8 de mayo de 2012

Infografías en Sanidad


Somos Medicina



Posted: 08 May 2012 02:27 PM PDT

Las infografías (derivado de gráficos de información) han aumentado en popularidad durante el último año. Con el nivel de infoxicación actual parece razonable pensar que un formato ideado para mostrar mucha información, manteniendo la sencillez y la estética, iba a triunfar. Eso y el boom de Pinterest, en el que la Big Pharma ha participado, hacen que las infografías también estén puedan tener un papel importante en la estrategia 2.0 de esta industria.
Ya hemos visto a organizaciones sin ánimo de lucro aprovecharse de este interés por la infografía para aumentar la concienciación sobre diferentes enfermedades como el lupus o el cáncer de páncreas. También muchas agencias gubernamentales relacionadas con la Salud en Estados Unidos han hecho uso de esta herramienta. Incluso la FDA ha usado infografías para difundir mensajes sobre el colesterol y los genéricos.
Sin embargo, sólo una compañía farmacéutica se ha lanzado a explotar esta posibilidad. Una búsqueda realizada por Eileen O'Brien para las patologías en que la Industria Farmacéutica invierte más dinero en publicidad (hipercolesterolemia, diabetes, insomnio) sólo ha devuelto dos resultados y ninguno pertenecía a las dosfarmas con perfil en Pinterest. La compañía Sanofi ha creado dos infografías bastante buenas sobre sus actividades durante el mes de la concienciación sobre Diabetes y para dar a conocer a mujeres pioneras con esta enfermedad.
Probablemente sea una visión sesgada, producto del interés actual en las infografías, pero creo que el uso de las infografías es una buena estrategia para las empresas biomédicas e instituciones sanitarias. Ayudan a entender datos complejos de forma atractiva y son muy fáciles de compartir en redes sociales o por email.
El ejemplo más parecido en España serían las recomendaciones sobre lavado de manos del Ministerio. Os he puesto en la cabecera unas cuantas infografías que podéis ampliar pulsando sobre ellas. ¿Conocéis alguna más que sea interesante? ¿Hay instituciones sanitarias haciendo infografías en español?

Lanza Biblioteca Digital Mexicana material digital sobre la Batalla de Puebla

http://www.milenio.com/cdb/doc/noticias2011/f91d79fe958aaaaba01a70324e2c8968


Lanza Biblioteca Digital Mexicana material digital sobre la Batalla de Puebla

CULTURA • 
Dicha biblioteca digitalizó siete documentos, entre ellos planos, caricaturas y una obra de teatro, así como una biografía de Ignacio Zaragoza.
México • Para conmemorar los 150 años de la batalla del 5 de mayo en Puebla, la Biblioteca Digital Mexicana (BDMX) digitalizó siete valiosos documentos, entre planos, caricaturas y una obra de teatro sobre la gesta, los cuales ya están disponibles en su sitio electrónico (http://bdmx.mx).
De acuerdo con el Consejo Nacional para la Cultura y las Artes (Conaculta), el Archivo General de la Nación contribuyó con un plano del ataque francés a la ciudad de Puebla y sus alrededores, trazado por las mismas fuerzas francesas para planear la ofensiva.
El documento señala los principales puntos donde se ubicaron los frentes de batalla, entre ellos Totimehuacan, Zaragoza, Guadalupe y Santa Anita.
Otros sitios de relevancia que marca son: Obrajes de Morelos, río Atoyac, Cholula, molino de Guadalupe , Loreto, Cerro de las Navajas, Garita de Tlaxcala, la catedral y el camino a Orizaba, entre otros.
La Biblioteca “Francisco Xavier Clavigero” de la Universidad Iberoamericana aportó la edición original de la descripción de la batalla del cinco de mayo de 1862 por el abate francés Jean Efrem de Lanusse (1818-1905), titulada “Les vaincus du cinq mai” (Los vencidos del cinco de mayo. 1867).
Se trata de un libro de gran formato, encuadernado y cuyas hojas están decoradas con motivos tales como flores y pájaros. Se dice que Lanusse fue el capellán del ejército francés en la invasión a México.
La Biblioteca Digital Mexicana cuenta también con un Plano de la batalla del cinco de mayo, bilingüe (México, 1862), procedente del Centro de Estudios de Historia de México CARSO.
Dicho documento contiene información tanto en español como en francés y fue mandado a hacer poco después de la batalla por el gobierno de Benito Juárez.
Incluye el parte de guerra del general Ignacio Zaragoza y una carta de ciudadanos franceses residentes en la ciudad de Puebla, para agradecer las atenciones dadas a los prisioneros y heridos franceses.
Además de la respuesta del gobernador y el anuncio del ministro de Guerra y Marina de la devolución a los franceses derrotados de las medallas y cruces que les fueron tomadas en la batalla.
Por su parte, la Biblioteca de México “José Vasconcelos” contribuyó a este trabajo con la “Biografía del General de División C. Ignacio Zaragoza”, de Manuel Z. Gómez Gómez, en la cual se da cuenta, entre otras cosas, de los decretos que se expidieron a consecuencia de la muerte de este afamado militar.
Mientras que la Nacional de Antropología, del Instituto Nacional de Antropología e Historia (INAH), hizo lo propio con “Las Glorias Nacionales. Álbum de la Guerra”, integrado por 11 folios del caricaturista y litógrafo Constantino Escalante, publicados por entregas, los nueve primeros en 1862 y 1863, los dos últimos en 1868.
Los dos últimos acompañados de descripciones literarias de Ignacio Manuel Altamirano y Guillermo Prieto.
La Biblioteca Digital Mexicana también incluyó una obra de teatro conmemorativa del 5 de mayo, procedente de la Biblioteca Cervantina del ITESM.
El montaje es de Justo Sierra, Enrique de Olavarría y Ferrari y Esteban González, y desde una óptica patriótica y en forma de versos aborda en un acto la gesta.

inexorable


inexorable
Esta palabra habla de cierta decisión que no va a ser modificada de manera alguna, no importa cuánto se ruegue al que la adoptó.
La palabra proviene del latín inexorabilis, un adjetivo que se aplicaba a aquel a quien no era posible conmover mediante ruegos ni oraciones porque era absolutamente inflexible. Veamos cómo está compuesta: orabilis es en latín "aquello que es posible pedir". Si se le añade el prefijo ex-, tenemos el vocablo exorabilis, que significa "que puede ser disuadido mediante ruegos", y también "que se deja corromper o sobornar". Inexorable sería, pues, aquel que no se deja convencer, que no es exorabilis. Horacio usa inexorabilis auro para denotar "que no se deja convencer por el oro".
Cabe añadir que orabilis proviene de orare 'rogar', 'pedir', 'solicitar', que se derivó, a su vez, de oris 'boca', presente también en oral, oración, orador, perorata y hasta en la palabra oráculo (de la pitonisa).

lunes, 7 de mayo de 2012

Opioides en pediatría


Prescribiendo medicación controlada a adolescentes y adultos jóvenes en los Estados Unidos 
Prescribing of controlled medications to adolescents and young adults in the United States.
Fortuna RJ, Robbins BW, Caiola E, Joynt M, Halterman JS.
Center for Primary Care, Culver Medical Group, University of Rochester School of Medicine and Dentistry, 913 Culver Rd, Rochester, NY 14609, USA. robert_fortuna@urmc.rochester.edu
Pediatrics. 2010 Dec;126(6):1108-16. Epub 2010 Nov 29.
Abstract
OBJECTIVE: The nonmedical use of prescription drugs by adolescents and young adults has surpassed all illicit drugs except marijuana, yet little is known about prescribing patterns. We examined the prescribing of controlled medications to adolescents aged 15 to 19 and young adults aged 20 to 29. METHODS: We used cross-sectional data from the National Ambulatory Medical Care Survey (N = 4304 physicians) and the National Hospital Ambulatory Medical Care Survey (N = 2805 clinics; N = 1051 emergency departments) between 2005 and 2007. We also used consecutive data from 1994 to describe trends. RESULTS: A controlled medication was prescribed at 2.3 million visits by adolescents and 7.8 million visits by young adults in 2007. Between 1994 and 2007, controlled medications were prescribed at an increasing proportion of visits from adolescents (6.4%-11.2%) and young adults (8.3%-16.1%) (P < .001 for trend). This increase was seen among males and females, in ambulatory offices and emergency departments, and for injury-related and non-injury-related visits (all P < .001). A controlled medication was prescribed during 9.6% of all adolescent visits and 13.8% of young-adult visits for non-injury-related indications and at 14.5% of adolescent visits and 27.0% of young-adult visits for injury-related reasons. Controlled medications were prescribed at a substantial proportion of visits for common conditions, such as back pain, to both adolescents (23.4%) and young adults (36.9%). CONCLUSIONS: Controlled medications are prescribed at a considerable proportion of visits from adolescents and young adults, and prescribing rates have nearly doubled since 1994. This trend and its relationship to misuse of medications warrants further study.

OPIOIDES EN NIÑOS 
Opioides en la práctica médica, editado por la Asociación Colombiana para el Estudio del Dolor, ACED. Bogotá, Colombia 2009.
SANDRA PATRICIA FLÓREZ ROJAS
INTRODUCCIÓN
Debido a múltiples características de los opioides, entre las que se encuentran su potencia, su eficacia y el bajo perfil de efectos secundarios, los opioides son el estándar para el control del dolor en múltiples escenarios, entre los que cabe destacar el control del dolor agudo postoperatorio y el dolor por cáncer principalmente. En la población pediátrica hay consideraciones importantes para su uso, especialmente en la población neonatal. El conocimiento de las diferencias farmacocinéticas y farmacodinámicas, asociado a un juicioso
monitoreo, permite que esta población se beneficie de su uso. La presente revisión pretende definir las características de los principales opioides de uso en la población pediátrica, las dosis y vías de administración más usadas y recomendaciones generales para su manejo.
http://www.dolor.org.co/libros/opioides/2-opioides_ninos.pdf

 
Atentamente
Dr. Enrique Hernández-Cortez
Anestesiología y Medicina del Dolor