jueves, 8 de octubre de 2015

Premio Nobel de química 2015

Octubre 8, 2015. No. 2108-AOctubre, mes de lucha contra cáncer de mama.
Anestesia y Dolor

Premio Nobel de química
Cellular secrets of DNA repair win Nobel Prize for chemistry
Tomas Lindahl, Paul Modrich, and Aziz Sancar
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Control de calidad de la reparación del ADN.
Quality control by DNA repair.
Science. 1999 Dec 3;286(5446):1897-905.
Abstract
Faithful maintenance of the genome is crucial to the individual and to species. DNA damage arises from both endogenous sources such as water and oxygen and exogenous sources such as sunlight and tobacco smoke. In human cells, base alterations are generally removed by excision repair pathways that counteract the mutagenic effects of DNA lesions. This serves to maintain the integrity of the genetic information, although not all of the pathways are absolutely error-free. In some cases, DNA damage is not repaired but is instead bypassed by specialized DNA polymerases.
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Modulo CEEA Leon, Gto. Curso CEEA Tijuana  XII Congreso Virtual Mexicano de Anestesiologia


          
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