jueves, 25 de febrero de 2016

Bibliotecas. Noticias


bibliotecas
Notificaciones diarias ⋅ 24 de febrero de 2016
NOTICIAS

Donación de libros, ante carencia en bibliotecas
Milenio.com
Donación de libros, ante carencia en bibliotecas. Pide regidor se haga una campaña de recolección y concientización casa por casa para rescatar ...




Puebla Noticias

Aperturan 4 bibliotecas públicas en juntas auxiliares de Teziutlán
Puebla Noticias
Teziutlán, Pue.- Las bibliotecas públicas de las juntas auxiliares de Mexcalcuautla, Atoluca, Acateno y San Sebastián han sido reabiertas y han dado ...




Noticanarias (Comunicado de prensa)

Antigua rechaza el pago por préstamo de libros en Bibliotecas Municipales
Noticanarias (Comunicado de prensa)
Antigua rechaza el pago por préstamo de libros en Bibliotecas Municipales ... de usuarios y los préstamos realizados en cada Biblioteca Municipal.



La biblioteca de Morella se integra en la Red de Bibliotecas Públicas de la Comunidad Valenciana
el periodic
La biblioteca de Morella ya pertenece a la Red de Bibliotecas Públicas de la Comunidad Valenciana, después de que ayer se publicará la adhesión ...




Murcia.com

El escritor Carles Cano visitará las bibliotecas para hablar de su obra, Querida Blanca
Murcia.com
Los estudiantes de tercero y cuarto de primaria de varios colegios cartageneros tendrán la oportunidad de conocer al autor Carles Cano y hablar con ...



La biblioteca de Luis Beltrán
rionegro.com.ar
La biblioteca popular Pablo Pizzurno se encuentra en una situación crítica. Desde hace varios meses no cuenta con bibliotecarios. La Secretaría de ...




ileon.com - Información de León

La Biblioteca de León acoge este jueves la conferencia 'Una educación para dignificar la vida'
Lainformacion.com
La Biblioteca Pública de León acoge este jueves, 25 de febrero, la conferencia 'Una educación para dignificar la vida', la tercera ponencia que se ...



Los recortes «obligarían» a cerrar los sábados la Biblioteca Regional
La Verdad
La Biblioteca Regional de Murcia, una de las instituciones culturales más importantes de la Región, además de más utilizadas y mejor valoradas por ...




Noticias de Álava

El sistema de Lectura Fácil se asienta en el territorio alavés
Noticias de Álava
En cuanto a los materiales, combinan la compra de títulos literarios con el uso de los que proporciona la Red de Bibliotecas municipales de Gasteiz.




La Rioja

La Biblioteca Pública de Ávila incorpora videojuegos a su catálogo de préstamos
El Norte de Castilla
La Biblioteca Publica de Ávila ha incorporado, por primera vez, el préstamo de un catálogo de 85 videojuegos. Podrán retirarse en la sección de ...

WEB

Qué es
Instituto Cervantes
Qué es. La biblioteca electrónica es un conjunto de recursos y servicios en línea de la red de bibliotecas del Instituto Cervantes. A través de la ...



Las tendencias de las bibliotecas académicas y de investigación del próximo lustro. Horizon Report
ub.edu
Por segundo año (consecutivo) el New Media Consortium (NMC) ha lanzado el informe de tendencias y retos para lasbibliotecas académicas y de ...



dibam y servicio civil firman convenio para utilización de bibliotecas en entrevistas para selección ...
Dibam
Un convenio de colaboración firmaron hoy los directores nacionales del Servicio Civil, Rodrigo Egaña, y de la Dirección de Bibliotecas Archivos y ...



Biblioteca de México
Biblioteca de México
De lunes a viernes del 29 de febrero al 12 de marzo de 2016, de 9 a 19 horas, en la oficina del Departamento de Promoción Cultural de la Biblioteca ...

Alerta edición 25 de Febrero 2016 Medwave

Alerta edición 25 de Febrero 2016 Medwave
Vea este email en su navegador


 

Los últimos artículos publicados en Medwave son los siguientes:
 
ARTÍCULO ESPECIAL
Vegetales como nuevas drogas psicoactivas: una revisión narrativa
Beatriz Rodríguez Salgado, Jorge Gómez-Arnau Ramírez, Daniel Sánchez Mateos, Helen Dolengevich Segal (España)

Medwave 2016 Ene;16(1):e6372
EDITORIAL
Decisión sobre vacunación anti-virus papiloma humano en Chile con dos dosis en vez de tres
Vivienne C. Bachelet (Chile)

Medwave 2016 Ene;16(1):e6373
REVISIÓN CLÍNICA
Revisión de las guías actuales de fibrilación auricular
José Kelvin Galvez-Olortegui, Mayita Lizbeth Álvarez-Vargas, Tomas Vladimir Galvez-Olortegui, Armando Godoy-Palomino, Luis Camacho-Saavedra (Perú)

Medwave 2016 Ene;16(1):6365
RESUMENES EPISTEMONIKOS
¿Es útil la terapia biológica para la psoriasis ungueal?
Andrea Antúnez-Lay, Jorge Cabrolier, Romina Andino-Navarrete (Chile)

Medwave 2016;16(Suppl 1):e6363
¿Es efectivo el ácido ursodeoxicólico en la colestasia intrahepática del embarazo?
Sebastián Sepúlveda Marín, Valeria Contreras Maragaño, Claudio Vera (Chile)

Medwave 2016;16(Suppl 1):e6361
 

 
¿Es necesaria la profilaxis antibiótica para el taponamiento nasal en epistaxis anterior?
Francisco Perez, Gabriel Rada (Chile)

Medwave 2016;16(Suppl 1):e6357
Para mayor información sobre nuestro proceso de publicación y revisión por pares Escribir a: Rodrigo Núñez, publishing@medwave.cl
 
Que tenga excelente día.

Copyright © 2016 Medwave Capacitación Ltda, Todos los derechos reservados
Este correo llega a usted, porque aceptó recibir información de nosotros a través de la página www.medwave.cl

Más de bupivacaina liposomal

Febrero 25, 2016. No. 2247


 



Bupivacaína liposomal como inyección simple en bloqueos de nervios periféricos: Estudio de dosis respuesta
Liposomal bupivacaine as a single-injection peripheral nerve block: a dose-response study.
Anesth Analg. 2013 Nov;117(5):1248-56. doi: 10.1213/ANE.0b013e31829cc6ae.
Abstract
BACKGROUND: Currently available local anesthetics approved for single-injection peripheral nerve blocks have a maximum duration of <24 hours. Aliposomal bupivacaine formulation (EXPAREL, Pacira Pharmaceuticals, Inc., San Diego, CA), releasing bupivacaine over 96 hours, recently gained Food and Drug Administration approval exclusively for wound infiltration but not peripheral nerve blocks. METHODS: Bilateral single-injection femoral nerve blocks were administered in healthy volunteers (n = 14). For each block, liposomal bupivacaine(0-80 mg) was mixed with normal saline to produce 30 mL of study fluid. Each subject received 2 different doses, 1 on each side, applied randomly in a double-masked fashion. The end points included the maximum voluntary isometric contraction (MVIC) of the quadriceps femoris muscle and tolerance to cutaneous electrical current in the femoral nerve distribution. Measurements were performed from baseline until quadriceps MVIC returned to 80% of baseline bilaterally. RESULTS: There were statistically significant dose responses in MVIC (0.09%/mg, SE = 0.03, 95% confidence interval [CI], 0.04-0.14, P = 0.002) and tolerance to cutaneous current (-0.03 mA/mg, SE = 0.01, 95% CI, -0.04 to -0.02, P < 0.001), however, in the opposite direction than expected (the higher the dose, the lower the observed effect). This inverse relationship is biologically implausible and most likely due to the limited sample size and the subjective nature of the measurement instruments. While peak effects occurred within 24 hours after block administration in 75% of cases (95% CI, 43%-93%), block duration usually lasted much longer: for bupivacaine doses >40 mg, tolerance to cutaneous current did not return to within 20% above baseline until after 24 hours in 100% of subjects (95% CI, 56%-100%). MVIC did not consistently return to within 20% of baseline until after 24 hours in 90% of subjects (95% CI, 54%-100%). Motor block duration was not correlated with bupivacaine dose (0.06 hour/mg, SE = 0.14, 95% CI, -0.27 to 0.39, P = 0.707). CONCLUSIONS: The results of this investigation suggest that deposition of a liposomal bupivacaine formulation adjacent to the femoral nerve results in a partial sensory and motor block of >24 hours for the highest doses examined. However, the high variability of block magnitude among subjects and inverse relationship of dose and response magnitude attests to the need for a phase 3 study with a far larger sample size, and that these results should be viewed as suggestive, requiring confirmation in a future trial.
Bupivacaína liposomal. Revisión de una nueva formulación de bupivacaína
Liposomal bupivacaine: a review of a new bupivacaine formulation.
J Pain Res. 2012;5:257-64. doi: 10.2147/JPR.S27894. Epub 2012 Aug 14.
Abstract
Many attempts have been made to increase the duration of local anesthetic action. One avenue of investigation has focused on encapsulating local anesthetics within carrier molecules to increase their residence time at the site of action. This article aims to review the literature surrounding the recently approved formulation of bupivacaine, which consists of bupivacaine loaded in multivesicular liposomes. This preparation increases the duration of local anesthetic action by slow release from the liposome and delays the peak plasma concentration when compared to plain bupivacaineadministration. Liposomal bupivacaine has been approved by the US Food and Drug Administration for local infiltration for pain relief after bunionectomy and hemorrhoidectomy. Studies have shown it to be an effective tool for postoperative pain relief with opioid sparing effects and it has also been found to have an acceptable adverse effect profile. Its kinetics are favorable even in patients with moderate hepatic impairment, and it has been found not to delay wound healing after orthopedic surgery. More studies are needed to establish its safety and efficacy for use via intrathecal, epidural, or perineural routes. In conclusion, liposomal bupivacaine is effective for treating postoperative pain when used via local infiltration when compared to placebo with a prolonged duration of action, predictable kinetics, and an acceptable side effect profile. However, more adequately powered trials are needed to establish its superiority over plain bupivacaine.
KEYWORDS: efficacy; liposomal bupivacaine; pharmacodynamics; pharmacokinetics; postoperative pain; safety

          
Anestesiología y Medicina del Dolor

52 664 6848905

Copyright © 2015

miércoles, 24 de febrero de 2016

Bupivacaina liposomal

Bupivacaína liposomal para tratar el dolor postoperatorio en artroplastia total unilateral
The use of exparel (liposomal bupivacaine) to manage postoperative pain in unilateral total knee arthroplasty patients.
J Arthroplasty 2015 Feb;30(2):325-9. doi: 10.1016/j.arth.2014.09.004. Epub 2014 Sep 16.
Abstract
Efforts continue to improve pain after total knee arthroplasty (TKA) in order to allow for accelerated rehabilitation. The purpose of this study was to evaluate pain control after TKA. A randomized prospective study of 80 consecutive patients was performed comparing Exparel versus femoral nerve block (FNB). Inpatient pain control was the primary outcome. Secondary outcome measures included ROM (extension and flexion), nausea and vomiting, narcotic consumption, ambulation distance, and length of stay (LOS). There were no statistically significant differences between the groups with regard to pain, nausea and vomiting, and narcotic consumption. The FNB group had greater flexion but the Exparel group had improved early ambulation and decreased LOS. Exparel provided similar pain relief to a FNB after TKA without compromising early rehabilitation.
KEYWORDS: accelerated rehabilitation; femoral nerve block; liposomal bupivacaine; total knee arthroplasty
Bupivacaína liposomal versus bupivacaína. Revisión comparativa
Bupivacaine liposomal versus bupivacaine: comparative review.
Hosp Pharm. 2014 Jun;49(6):539-43. doi: 10.1310/hpj4906-539.
Abstract
Bupivacaine liposomal injection was recently approved by the US Food and Drug Administration (FDA) as a local anesthetic for use in management of postsurgical pain in adults. When compared to placebo, bupivacaine liposomal decreases postoperative pain and opioid use. This review examines the efficacy of bupivacaine liposomal when compared to conventional bupivacaine ± epinephrine using published and unpublished data provided to the FDA by the manufacturer.
KEYWORDS: bupivacaine; bupivacaine liposomal; formulary; pharmacoeconomics

          
Anestesiología y Medicina del Dolor

52 664 6848905

Copyright © 2015

lunes, 22 de febrero de 2016

Canabinoides, su utilidad en neurología pediátrica

Estimado Ciberpediatra te invito al Seminario de Pediatría, Cirugía Pediátrica y Lactancia Materna. El día 24 Febrero 2016 las 21hrs (Centro, México DF, Guadalajara y Lima Perú) a la Conferencia: “Canabinoides, su utilidad en neurología pediátrica ” por el “Dr. Carlos Aguirre Velázquez”, Neurólogo, Pediatra de la Cd. de Monterrey N.L.. La sesión inicia puntualmente las 21 hrs.
Para entrar a la Sala de Conferencia:
1.- hacer click en la siguiente liga, o cópiala y escríbela en tu buscador 
http://connectpro60196372.adobeconnect.com/canabinoides_pediatria/

2.- “Entra como Invitado” Escribes tu nombre y apellido en el espacio en blanco
3.- Hacer click en el espacio que dice “Entrar en la Sala”
5.- A disfrutar la conferencia
6.- Recomendamos que dejes tu Nombre Completo, Correo electrónico y que participes.


Dr. Enrique Mendoza López Webmaster: CONAPEME Coordinador Nacional: Seminario Ciberpeds-Conapeme Av La clinica 2520-310 Colonia Sertoma ,Mty N.L. México CP 64710 Tel-Fax 52 81 83482940 y 52 81 81146053 Celular 8183094806 www.conapeme.org www.pediatramendoza.com enrique@pediatramendoza.com emendozal@yahoo.com.mx

jueves, 18 de febrero de 2016

Tromboembolia pulmonar / Pulmonary embolism

Febrero 15, 2016. No. 2238


 



 Epidemiología del tromboembolismo venoso
The epidemiology of venous thromboembolism.
J Thromb Thrombolysis. 2016 Jan;41(1):3-14. doi: 10.1007/s11239-015-1311-6.
Abstract
Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, active cancer, trauma or fracture, immobility or leg paresis, superficial vein thrombosis, and, in women, pregnancy and puerperium, oral contraception, and hormone therapy. Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing.
KEYWORDS: Deep vein thrombosis; Epidemiology; Pulmonary embolism; Thrombophlebitis; Venous thromboembolism
Importancia de los factores de riesgo en la evaluación de pacientes con sospecha de TEP
Importance of risk factors for the evaluation of patients with a suspected pulmonary embolism.
Exp Ther Med. 2015 Jun;9(6):2281-2284. Epub 2015 Mar 30.
Abstract
The reliable exclusion of a pulmonary embolism (PE) in hemodynamically stable patients remains a challenge. The European Society of Cardiology guidelines for PE diagnosis published in 2008 and updated in 2014 recommend a low-threshold computed tomography (CT) indication for patients with a high probability of pulmonary embolism or those with elevated levels of D-dimers. Certain elements of the recommendations are controversial, while others, including the evaluation of the risk factors for PE, are considered only in individual cases. In the present study, various risk factors, including obesity, smoking, contraceptive use, immobility level, history of malignant disease and thrombophilia and the factors of familial predisposition, deep vein thrombosis (DVT)/PE-history, long-distance flying <1 week and surgery <4 weeks previously, were retrospectively examined in 492 patients with a suspected PE. The data demonstrated a significant risk of PE with contraceptive use, a history of DVT/PE and thrombophilia. The immobility level, surgery <4 weeks and long-distance flying <1 week previously, as well as family history, malignant disease,obesity and smoking, were not observed to be associated with a significantly higher risk of PE. Contraceptive use and thrombophilia, in addition to a history of DVT/PE, each appear to have a significant predictive value in the context of PE risk stratification. Therefore, patients with a suspected PE, who additionally present with at least one of the aforementioned risk factors, should undergo further diagnostic steps for PE risk stratification, including a low-threshold CT examination, even in the absence of elevated D-dimers.
KEYWORDS: emergency department; pulmonary embolism; risk factors
Revisión del costo de tromboembolismo venoso
Review of the cost of venous thrombembolism.
Clinicoecon Outcomes Res. 2015 Aug 28;7:451-62. doi: 10.2147/CEOR.S85635. eCollection 2015.
Abstract
BACKGROUND: Venous thromboembolism (VTE) is the second most common medical complication and a cause of excess length of hospital stay. Its incidence and economic burden are expected to increase as the population ages. We reviewed the recent literature to provide updated cost estimates on VTE management. METHODS: Literature search strategies were performed in PubMed, Embase, Cochrane Collaboration, Health Economic Evaluations Database, EconLit, and International Pharmaceutical Abstracts from 2003-2014. Additional studies were identified through searching bibliographies of related publications. RESULTS: Eighteen studies were identified and are summarized in this review; of these, 13 reported data from the USA, four from Europe, and one from Canada. Three main cost estimations were identified: cost per VTE hospitalization or per VTE readmission; cost for VTE management, usually reported annually or during a specific period; and annual all-cause costs in patients with VTE, which included the treatment of complications and comorbidities. Cost estimates per VTE hospitalization were generally similar across the US studies, with a trend toward an increase over time. Cost per pulmonary embolism hospitalization increased from $5,198-$6,928 in 2000 to $8,764 in 2010. Readmission for recurrent VTE was generally more costly than the initial index event admission. Annual health plan payments for services related to VTE also increased from $10,804-$16,644 during the 1998-2004 period to an estimated average of $15,123 for a VTE event from 2008 to 2011. Lower costs for VTE hospitalizations and annualized all-cause costs were estimated in European countries and Canada. CONCLUSION: Costs for VTE treatment are considerable and increasing faster than general inflation for medical care services, with hospitalization costs being the primary cost driver. Readmissions for VTE are generally more costly than the initial VTE admission. Further studies evaluating the economic impact of new treatment options such as the non-vitamin K antagonist oral anticoagulants on VTE treatment are warranted.
KEYWORDS: costs; deep vein thrombosis; pharmacoeconomics; pulmonary embolism; resource utilization
JACCOA


          
Anestesiología y Medicina del Dolor

52 664 6848905

Copyright © 2015