martes, 23 de enero de 2018

Neurociencias / Neuroscience

Enero 23, 2018. No. 2972
Redes de cerebro a múltiples escalas.
Multi-scale brain networks.
Neuroimage. 2017 Oct 15;160:73-83. doi: 10.1016/j.neuroimage.2016.11.006. Epub 2016 Nov 11.
Abstract
The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its alteration in disease or injury. Traditional tools and approaches to study this architecture have largely focused on single scales-of topology, time, and space. Expanding beyond this narrow view, we focus this review on pertinent questions and novel methodological advances for the multi-scale brain. We separate our exposition into content related to multi-scale topological structure, multi-scale temporal structure, and multi-scale spatial structure. In each case, we recount empirical evidence for such structures, survey network-based methodological approaches to reveal these structures, and outline current frontiers and open questions. Although predominantly peppered with examples from human neuroimaging, we hope that this account will offer an accessible guide to any neuroscientist aiming to measure, characterize, and understand the full richness of the brain's multiscale network structure-irrespective of species, imaging modality, or spatial resolution.
KEYWORDS: Brain networks; Complex networks; Graph theory; Multi-layer; Multi-resolution; Multi-scale; Network neuroscience
Neuromodulación no invasiva de nervios craneales: nuevo enfoque para la neuro-rehabilitación.
Cranial Nerve Noninvasive Neuromodulation: New Approach to Neurorehabilitation.
Authors
In: Kobeissy FH1, editor. 
Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Boca Raton (FL): CRC Press/Taylor & Francis; 2015. Chapter 44.
Frontiers in Neuroengineering.
Neurociencias
NEUROSCIENCE
Third Edition, 2004
Safe Anaesthesia Worldwide
Delivering safe anaesthesia to the world's poorest people
World Congress on Regional Anesthesia & Pain Medicine
April 19-21, 2018, New York City, USA
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Anestesiología y Medicina del Dolor

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Manejo del dolor articular acromio-clavicular: una revisión del alcance

http://www.mihombroycodo.com.mx/academia/manejo-del-dolor-articular-acromio-clavicular-una-revision-del-alcance/

Managing acromio-clavicular joint pain: a scoping review


Fuente
Este artículo es publicado originalmente en:

https://www.ncbi.nlm.nih.gov/pubmed/29276532

http://journals.sagepub.com/doi/10.1177/1758573217700839

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734523/


De:

Chaudhury S1, Bavan L1, Rupani N1, Mouyis K1, Kulkarni R2, Rangan A3, Rees J1.

2018 Jan;10(1):4-14. doi: 10.1177/1758573217700839. Epub 2017 Apr 9.


Todos los derechos reservados para:

Copyright © 2018 by The British Elbow & Shoulder Society


Abstract

Background:

Shoulder pain secondary to acromioclavicular joint pain is a common presentation in primary and secondary care but is often poorly managed as a result of uncertainty about optimal treatment strategies. Osteoarthritis is the commonest cause. Although acromioclavicular pain can be treated non-operatively and operatively, there appears to be no consensus on the best practice pathway of care for these patients, with variations in treatment being common place. The present study comprises a scoping review of the current published evidence for the management of isolated acromioclavicular pain (excluding acromioclavicular joint dislocation).

Conclusions:

High-level studies on treatment modalities for acromioclavicular joint pain are limited. As such, there remains little evidence to support one intervention or treatment over another, making it difficult to develop any evidenced-based patient pathways of care for this condition.Level of evidence: 2A.

KEYWORDS:

acromioclavicular joint; arthroscopic surgery; corticosteroid injection; distal clavicular excision; pain


Resumen


ANTECEDENTES:

El dolor de hombro secundario al dolor de la articulación acromioclavicular es una presentación común en la atención primaria y secundaria, pero a menudo se trata de manera deficiente como resultado de la incertidumbre sobre las estrategias de tratamiento óptimas. La osteoartritis es la causa más común. Aunque el dolor acromioclavicular puede tratarse de forma no operativa y operativa, parece que no hay consenso sobre la mejor forma de atención para estos pacientes, con variaciones en el tratamiento que es el lugar común. El presente estudio comprende una revisión del alcance de la evidencia publicada actual para el tratamiento del dolor acromioclavicular aislado (excluyendo la luxación de la articulación acromioclavicular).

Conclusiones

Los estudios de alto nivel sobre las modalidades de tratamiento para el dolor articular acromioclavicular son limitados. Como tal, queda poca evidencia para respaldar una intervención o tratamiento sobre otra, lo que dificulta el desarrollo de las vías de atención del paciente basadas en la evidencia para esta afección. Nivel de evidencia: 2A.

PALABRAS CLAVE:

articulación acromioclavicular; cirugía artroscópica; inyección de corticosteroides; escisión clavicular distal; dolor


PMID: 29276532  PMCID:  PMC5734523  [Available on 2019-01-01]
DOI: 10.1177/1758573217700839

lunes, 22 de enero de 2018

Los pacientes que viven solos pueden ser dados de alta de forma segura directamente a casa después de una artroplastia articular total: un estudio de cohortes prospectivo

http://www.mishuesosyarticulaciones.com.mx/artroplastia/los-pacientes-que-viven-solos-pueden-ser-dados-de-alta-de-forma-segura-directamente-a-casa-despues-de-una-artroplastia-articular-total-un-estudio-de-cohortes-prospectivo/


Patients Living Alone Can Be Safely Discharged Directly Home After Total Joint Arthroplasty: A Prospective Cohort Study


Fuente
Este artículo es originalmente publicado en:

https://www.ncbi.nlm.nih.gov/pubmed/29342059

https://insights.ovid.com/crossref?an=00004623-201801170-00002


De:

Fleischman AN1, Austin MS1, Purtill JJ1, Parvizi J1, Hozack WJ1.

2018 Jan 17;100(2):99-106. doi: 10.2106/JBJS.17.00067.


Todos los derechos reservados para:

Copyright © 2017 Ovid Technologies, Inc., and its partners and affiliates. All Rights Reserved.
Some content from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.


Abstract

BACKGROUND:

Despite the expense and potential hazards of inpatient rehabilitation, there is a prevailing belief that patients living alone cannot be safely discharged directly home after total joint arthroplasty. The purpose of this study was to assess the safety and efficacy of direct home discharge for patients living alone during convalescence after primary total joint arthroplasty.

CONCLUSIONS:

Patients living alone had a safe and manageable recovery when discharged directly home after total joint arthroplasty. Extending the initial hospitalization and providing home health services on a selected basis may be a more cost-effective approach than routine discharge to an inpatient rehabilitation facility.


Resumen


ANTECEDENTES:

A pesar del costo y los peligros potenciales de la rehabilitación hospitalaria, existe la creencia predominante de que los pacientes que viven solos no pueden ser dados de alta de manera segura directamente a casa después de la artroplastia total de articulaciones. El objetivo de este estudio fue evaluar la seguridad y la eficacia de la descarga domiciliaria directa en pacientes que viven solos durante la convalecencia después de la artroplastia total primaria de articulaciones.

CONCLUSIONES:

Los pacientes que viven solos tuvieron una recuperación segura y manejable cuando fueron dados de alta directamente a casa después de la artroplastia total de articulaciones. Extender la hospitalización inicial y proporcionar servicios de atención domiciliaria en una base seleccionada puede ser un enfoque más rentable que la descarga de rutina a un centro de rehabilitación para pacientes hospitalizados.

PMID:  29342059  DOI:  10.2106/JBJS.17.00067

Embarazo en Adolescentes, Por el Dr. Francisco Fernández Paredes

Hola, Estimado Ciberpediatra

lo invitamos a unirse al seminario web Zoom.

Cuándo: ene 24, 2018 9:00 PM Ciudad de México

Tema: Embarazo en Adolescentes, Por el Dr. Francisco Fernández Paredes

Haga clic en el enlace a continuación para unirse al seminario web:

https://zoom.us/j/506960495



O un toque en iPhone :

Estados Unidos: +16468769923,,506960495# or +16699006833,,506960495#

O teléfono:

Marcar:

Estados Unidos: +1 646 876 9923 or +1 669 900 6833 or +1 408 638 0968

ID de seminario web: 506 960 495

Números internacionales disponibles: https://zoom.us/zoomconference?m=G-l4nXSC8OFamILIAnlL7qWXKdzg-VTA

XcfjeWMjs

Recomendamos que bajes e instales el programa Zoom en tu computadora, para poder accesar la reunion

Henrys

--

Dr. Enrique Mendoza López
Webmaster: CONAPEME
Coordinador Nacional: Seminario Ciberpeds-Conapeme
Av La Clinica 2520-310 col Sertoma
Monterrey N.L. CP 64718
Tel (81) 83482940, (81)81146053
Cel 0448183094806
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Dolor en pediatría / Pediatric pain

Enero 20, 2018. No. 2969
Los enfoques metodológicos actuales en la evaluación de la modulación condicionada del dolor en pediatría.
Current methodological approaches in conditioned pain modulation assessment in pediatrics.
Hwang PS1, Ma ML1,2,3, Spiegelberg N1, Ferland CE1,2,3,4,5.
J Pain Res. 2017 Dec 12;10:2797-2802. doi: 10.2147/JPR.S150857. eCollection 2017.
Abstract
Conditioned pain modulation (CPM) paradigms have been used in various studies with healthy and non-healthy adult populations in an attempt to elucidate the mechanisms of pain processing. However, only a few studies so far have applied CPM in pediatric populations. Studies finding associations with chronic pain conditions suggest that deficiencies in underlying descending pain pathways may play an important role in the development and persistence of pain early in life. Twelve studies were identified using a PubMed search which examine solely pediatric populations, and these are reviewed with regard to demographics studied, methodological approaches, and conclusions reached. This review aimed to provide both clinicians and researchers with a brief overview of the current state of research regarding the use of CPM in children and adolescents, both healthy and clinical patients. The implications of CPM in experimental and clinical settings and its potential to aid in refining considerations to individualize treatment of pediatric pain syndromes will be discussed.
KEYWORDS: chronic pain; conditioned pain modulation; descending endogenous pain inhibition; pediatrics
Safe Anaesthesia Worldwide
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World Congress on Regional Anesthesia & Pain Medicine
April 19-21, 2018, New York City, USA
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Anestesiología y Medicina del Dolor

52 664 6848905

Sistema glimfático cerebral / The brain glymphatic system

Enero 21, 2018. No. 2970
El sistema glimfático cerebral fue descrito por Maiken Nedergaard, y nombrado así por la participación de la neuroglia. Los descubrimientos han demostrado que es una vía peri vascular de eliminación de productos metabólicos del cerebro (función pseudolinfática) en el cual los astrocitos juegan un papel vital. Se le ha relacionado con la fisiología cerebral y algunas enfermedades del SNC y la posibilidad de manipularlo con efectos terapéuticos que sin duda pronto estaremos utilizando en clínica.
Hoy y mañana enviaremos información disponible con acceso abierto sobre este interesante tópico.
The glymphatic system was described by Maiken Nedergaard, and named for the participation of the neuroglia. The discoveries have shown that it is a peri-vascular pathway for the elimination of metabolic products from the brain (pseudolymphatic function), in which astrocytes play a vital role. It has been related to brain physiology and some CNS diseases, and the possibility of manipulating it with therapeutic effects that we will soon be using in the clinic.
Today and tomorrow we will send information available with open access on this interesting topic.
¿Hay un sistema linfático cerebral?
Is there a cerebral lymphatic system?
Stroke. 2013 Jun;44(6 Suppl 1):S93-5. doi: 10.1161/STROKEAHA.112.678698.
El camino paravascular para la eliminación de desechos cerebrales: comprensión actual, importancia y controversia.
The Paravascular Pathway for Brain Waste Clearance: Current Understanding, Significance and Controversy.
Front Neuroanat. 2017 Nov 7;11:101. doi: 10.3389/fnana.2017.00101. eCollection 2017.
Abstract
The paravascular pathway, also known as the "glymphatic" pathway, is a recently described system for waste clearance in the brain. According to this model, cerebrospinal fluid (CSF) enters the paravascular spaces surrounding penetrating arteries of the brain, mixes with interstitial fluid (ISF) and solutes in the parenchyma, and exits along paravascular spaces of draining veins. Studies have shown that metabolic waste products and solutes, including proteins involved in the pathogenesis of neurodegenerative diseases such as amyloid-beta, may be cleared by this pathway. Consequently, a growing body of research has begun to explore the association between glymphatic dysfunction and various disease states. However, significant controversy exists in the literature regarding both the direction of waste clearance as well as the anatomical space in which the waste-fluid mixture is contained. Some studies have found no evidence of interstitial solute clearance along the paravascular space of veins. Rather, they demonstrate a perivascular pathway in which waste is cleared from the brain along an anatomically distinct perivascular space in a direction opposite to that of paravascular flow. Although possible explanations have been offered, none have been able to fully reconcile the discrepancies in the literature, and many questions remain. Given the therapeutic potential that a comprehensive understanding of brain waste clearance pathways might offer, further research and clarification is highly warranted.
KEYWORDS: amyloid-beta; brain waste clearance; glymphatic system; paravascular pathway; perivascular pathway
Comprendiendo las funciones y relaciones del sistema glimfático y linfático meníngeo.
Understanding the functions and relationships of the glymphatic system and meningeal lymphatics.
J Clin Invest. 2017 Sep 1;127(9):3210-3219. doi: 10.1172/JCI90603. Epub 2017 Sep 1.
Abstract
Recent discoveries of the glymphatic system and of meningeal lymphatic vessels have generated a lot of excitement, along with some degree of skepticism. Here, we summarize the state of the field and point out the gaps of knowledge that should be filled through further research. We discuss the glymphatic system as a system that allows CNS perfusion by the cerebrospinal fluid (CSF) and interstitial fluid (ISF). We also describe the recently characterized meningeal lymphatic vessels and their role in drainage of the brain ISF, CSF, CNS-derived molecules, and immune cells from the CNS and meninges to the peripheral (CNS-draining) lymph nodes. We speculate on the relationship between the two systems and their malfunction that may underlie some neurological diseases. Although much remains to be investigated, these new discoveries have changed our understanding of mechanisms underlying CNS immune privilege and CNS drainage. Future studies should explore the communications between the glymphatic system and meningeal lymphatics in CNS disorders and develop new therapeutic modalities targeting these systems.
Safe Anaesthesia Worldwide
Delivering safe anaesthesia to the world's poorest people
World Congress on Regional Anesthesia & Pain Medicine
April 19-21, 2018, New York City, USA
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Anestesiología y Medicina del Dolor

52 664 6848905