#Osteopetrosis makes bones overly dense, but weak & easily fractured. Info on symptoms, treatments & research: 1.usa.gov/16wHP8i
— NIAMS/NIH/DHHS (@NIH_NIAMS) 2 de abril de 2013
Revisiones bibliográficas. Documentación científica en Ortopedia y Traumatología, medicina deportiva, artroscopia, artroplastia y de todas las patologías del sistema Músculo-Esquelético
viernes, 24 de mayo de 2013
#Osteopetrosis makes bones overly dense, but weak & easily fractured
Osteopetrosis
AR #osteopetrosis is a rare #lethal #disorder resulting in a bone marrow cavity insufficient to support #hematopoiesis. cags.org.ae/pdf/259700.pdf
— Arab Genomic Studies (@CAGS_UAE) 12 de febrero de 2012
Una clave para reducir la osteoartritis
Una clave para reducir la osteoartritis Hasta ahora, sólo podíamos proponer a reducir los..reflexions.ulg.ac.be/cms/c_44577/un… twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
Artroscopia de Cadera
Artroscopia de CaderaSe trata de una cirugía mínimamente invasiva en la que ....camde.es/artroscopia-de… twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
Las sociedades científicas deberían liderar la creación de un protocolo de actuación en artrosis
Sociedades científicas deberían liderar la creación de un protocolo de actuación en artrosiscondroprotectores.es/prof-antonio-g… twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
Booksupdate. NYT
Book
http://www.nytimes.com/indexes/2013/05/24/books/booksupdate/index.html
May 24, 2013
Books Update
'The Hanging Garden'
By PATRICK WHITE
Reviewed by JOHN SUTHERLAND
In the eyes of Patrick White's two refugee children, most Australians are horrible and very few are kind.
'Between My Father and the King: New and Uncollected Stories'
By JANET FRAME
Reviewed by ALISON McCULLOCH
Janet Frame was saved from undergoing a lobotomy when a book of her stories won a local literary prize.
Also in the Book Review
Maria Semple: By the Book
The author of "Where'd You Go, Bernadette" calls Franzen her "big daddy" - "My favorite kind of book is a domestic drama that's grounded in reality yet slightly unhinged."
By the Book: Archive
'Forty-One False Starts: Essays on Artists and Writers'
By JANET MALCOLM
Reviewed by ADAM KIRSCH
Janet Malcolm's penetrating profiles are case studies in defeated amour-propre.
'My Bright Abyss: Meditation of a Modern Believer'
By CHRISTIAN WIMAN
Reviewed by KATHLEEN NORRIS
The poet Christian Wiman ruminates on his incurable illness and his return to Christian belief.
''til Faith Do Us Part: How Interfaith Marriage Is Transforming America'
By NAOMI SCHAEFER RILEY
Reviewed by GUSTAV NIEBUHR
An exploration of how, or if, interfaith marriages work in a nation of many religions.
'Flora'
By GAIL GODWIN
Reviewed by LEAH HAGER COHEN
Gail Godwin's novel is populated almost exclusively by orphans of various stripes.
'Waiting to Be Heard: A Memoir'
By AMANDA KNOX
Reviewed by SAM TANENHAUS
Amanda Knox tells her story of being charged with murder in Italy.
'You Are One of Them'
By ELLIOTT HOLT
Reviewed by MAGGIE SHIPSTEAD
Amid entanglements between Russia and young Americans, a first novel explores the sense of betrayal in the loss of family and friends.
'Hollywood and Hitler, 1933-1939'
By THOMAS DOHERTY
Reviewed by DAVE KEHR
The movie industry ignored the growing German menace.
'The Guns at Last Light: The War in Western Europe, 1944-1945'
By RICK ATKINSON
Reviewed by BEN MACINTYRE
The final volume of Rick Atkinson's trilogy shows that the road to Berlin was far from smooth.
'Return of a King: The Battle for Afghanistan, 1839-42'
By WILLIAM DALRYMPLE
Reviewed by JOHN DARWIN
William Dalrymple seeks contemporary lessons in Britain's disastrous 19th-century invasion of Afghanistan.
CRIME
Uneasy Streets
By MARILYN STASIO
Walter Mosley is never better than when he's got a juicy cut of history to chew on - this time the late '60s.
Nonfiction Chronicle
New books by Mark S. Weiner, Andrew T. Guzman, Ben Goldacre, Daniel Brook and Vishaan Chakrabarti.
BEST SELLERS
Combined Print & E-Book Fiction
Combined Print & E-Book Nonfiction
Hardcover Fiction
Hardcover Nonfiction
Paperback Trade Fiction
Paperback Mass-Market Fiction
Paperback Nonfiction
All the Lists
OPEN BOOK
Battle of the Brain
By JOHN WILLIAMS
The National Institute of Mental Health has distanced itself from the "D.S.M.," the so-called bible of psychiatry, the fifth edition of which is published this week.
Back Page
Bulgakov's Ghost
By EMILY PARKER
Some Russians say literature had more political power when it was forbidden.
TBR
Inside the List
By GREGORY COWLES
Crime sellers in the spotlight and Dan Brown's "Inferno" makes its debut on the hardcover fiction list at No. 1.
Editors' Choice
Recently reviewed books of particular interest.
Paperback Row
By IHSAN TAYLOR
Paperback books of particular interest.
Book Review Podcast
This week, Helene Wecker discusses her novel "The Golem and the Jinni"; Julie Bosman has notes from the field; David Carr talks about David Sedaris's "Let's Explore Diabetes With Owls"; and Gregory Cowles has best-seller news. Pamela Paul is the host.
Book Review Podcast: Lamenting Defectors, Soviet and Otherwise
Rick Atkinson to Write Trilogy about the American Revolution
Ethan Coen Play to Open Atlantic Theater Company Season
REVIEWS BY THE TIMES'S CRITICS
'The Art of Controversy' by Victor Navasky
'Straight Flush' by Ben Mezrich
'Southern Cross the Dog' by Bill Cheng
'And the Mountains Echoed' by Khaled Hosseini
'Americanah' by Chimamanda Ngozi Adichie
CHILDREN'S BOOKS
Children's Books: Whatever Happened to the Big Bad Wolf?
ARCHIVE
Crime Columns
Children's Books
The New York Times Book Review: Back Issues
Editor's Note
Thanks for taking the time to read this e-mail. Feel free to send feedback; I enjoy hearing your opinions and will do my best to respond.
John Williams
Senior Staff Editor
The New York Times on the Web
http://www.nytimes.com/indexes/2013/05/24/books/booksupdate/index.html
May 24, 2013
Books Update
'The Hanging Garden'
By PATRICK WHITE
Reviewed by JOHN SUTHERLAND
In the eyes of Patrick White's two refugee children, most Australians are horrible and very few are kind.
'Between My Father and the King: New and Uncollected Stories'
By JANET FRAME
Reviewed by ALISON McCULLOCH
Janet Frame was saved from undergoing a lobotomy when a book of her stories won a local literary prize.
Also in the Book Review
Maria Semple: By the Book
The author of "Where'd You Go, Bernadette" calls Franzen her "big daddy" - "My favorite kind of book is a domestic drama that's grounded in reality yet slightly unhinged."
By the Book: Archive'Forty-One False Starts: Essays on Artists and Writers'
By JANET MALCOLM
Reviewed by ADAM KIRSCH
Janet Malcolm's penetrating profiles are case studies in defeated amour-propre.
'My Bright Abyss: Meditation of a Modern Believer'
By CHRISTIAN WIMAN
Reviewed by KATHLEEN NORRIS
The poet Christian Wiman ruminates on his incurable illness and his return to Christian belief.
''til Faith Do Us Part: How Interfaith Marriage Is Transforming America'
By NAOMI SCHAEFER RILEY
Reviewed by GUSTAV NIEBUHR
An exploration of how, or if, interfaith marriages work in a nation of many religions.
'Flora'
By GAIL GODWIN
Reviewed by LEAH HAGER COHEN
Gail Godwin's novel is populated almost exclusively by orphans of various stripes.
'Waiting to Be Heard: A Memoir'
By AMANDA KNOX
Reviewed by SAM TANENHAUS
Amanda Knox tells her story of being charged with murder in Italy.
'You Are One of Them'
By ELLIOTT HOLT
Reviewed by MAGGIE SHIPSTEAD
Amid entanglements between Russia and young Americans, a first novel explores the sense of betrayal in the loss of family and friends.
'Hollywood and Hitler, 1933-1939'
By THOMAS DOHERTY
Reviewed by DAVE KEHR
The movie industry ignored the growing German menace.
'The Guns at Last Light: The War in Western Europe, 1944-1945'
By RICK ATKINSON
Reviewed by BEN MACINTYRE
The final volume of Rick Atkinson's trilogy shows that the road to Berlin was far from smooth.
'Return of a King: The Battle for Afghanistan, 1839-42'
By WILLIAM DALRYMPLE
Reviewed by JOHN DARWIN
William Dalrymple seeks contemporary lessons in Britain's disastrous 19th-century invasion of Afghanistan.
CRIME
Uneasy Streets
By MARILYN STASIO
Walter Mosley is never better than when he's got a juicy cut of history to chew on - this time the late '60s.
Nonfiction Chronicle
New books by Mark S. Weiner, Andrew T. Guzman, Ben Goldacre, Daniel Brook and Vishaan Chakrabarti.
BEST SELLERS
Combined Print & E-Book Fiction
Combined Print & E-Book Nonfiction
Hardcover Fiction
Hardcover Nonfiction
Paperback Trade Fiction
Paperback Mass-Market Fiction
Paperback Nonfiction
All the Lists
OPEN BOOK
Battle of the Brain
By JOHN WILLIAMS
The National Institute of Mental Health has distanced itself from the "D.S.M.," the so-called bible of psychiatry, the fifth edition of which is published this week.
Back Page
Bulgakov's Ghost
By EMILY PARKER
Some Russians say literature had more political power when it was forbidden.
TBR
Inside the List
By GREGORY COWLES
Crime sellers in the spotlight and Dan Brown's "Inferno" makes its debut on the hardcover fiction list at No. 1.
Editors' Choice
Recently reviewed books of particular interest.
Paperback Row
By IHSAN TAYLOR
Paperback books of particular interest.
Book Review Podcast
This week, Helene Wecker discusses her novel "The Golem and the Jinni"; Julie Bosman has notes from the field; David Carr talks about David Sedaris's "Let's Explore Diabetes With Owls"; and Gregory Cowles has best-seller news. Pamela Paul is the host.
Book Review Podcast: Lamenting Defectors, Soviet and Otherwise
Rick Atkinson to Write Trilogy about the American Revolution
Ethan Coen Play to Open Atlantic Theater Company Season
REVIEWS BY THE TIMES'S CRITICS
'The Art of Controversy' by Victor Navasky
'Straight Flush' by Ben Mezrich
'Southern Cross the Dog' by Bill Cheng
'And the Mountains Echoed' by Khaled Hosseini
'Americanah' by Chimamanda Ngozi Adichie
CHILDREN'S BOOKS
Children's Books: Whatever Happened to the Big Bad Wolf?
ARCHIVE
Crime Columns
Children's Books
The New York Times Book Review: Back Issues
Editor's Note
Thanks for taking the time to read this e-mail. Feel free to send feedback; I enjoy hearing your opinions and will do my best to respond.
John Williams
Senior Staff Editor
The New York Times on the Web
39° Congreso Argentino de Cirugía de la Mano16° Congreso Argentino de Terapistas de la Mano
39° Congreso Argentino de Cirugía de la Mano16° Congreso Argentino de Terapistas de la Manocongresoargentinomano2013.org twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
CURSO "PEDI@TÍPS ORTOPÉDICOS"
SE INVITA AL CURSO"PEDI@TÍPS ORTOPÉDICOS" México, 26/27/28/2013INP ,ATTE. DR. JOSE CORTES GOMEZ twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
#hip #arthroscopy
#hip #arthroscopy "the patient must be properly positioned for the procedure to go well. Poor positioning will assure a difficult procedure"
— Dr. David Maldonado (@traumatologoalD) 22 de mayo de 2013
Ketamina para depresión/Ketamine and depression
Ketamina oral para tratamiento rápido de la depresión y ansiedad en pacientes que reciben manejo en hospicios
Oral ketamine for the rapid treatment of depression and anxiety in patients receiving hospice care.
Irwin SA, Iglewicz A.
Institute for Palliative Medicine at San Diego Hospice, Palliative Care Psychiatry, San Diego, California 92103, USA. sirwin@sdhospice.org
J Palliat Med. 2010 Jul;13(7):903-8. doi: 10.1089/jpm.2010.9808.
Abstract
Depression is prevalent and undertreated in patients receiving hospice care. Standard antidepressants do not work rapidly or often enough to benefit most of these patients. Here, two cases are reported in which a single oral dose of ketamine provided rapid and moderately sustained symptom relief for both depression and anxiety. In addition, no adverse effects were noted. Further investigation with randomized, controlled clinical trials is necessary to firmly establish the effectiveness of oral ketamine for the treatment of depression and anxiety in patients receiving hospice care. Ketamine may be a promising safe, effective, and cost-effective rapid treatment for depression and anxiety in this population.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120058/pdf/jpm.2010.9808.pdf
El bloqueo del receptor NMDA en reposo desencadena respuestas antidepresivas conductuales rápidas
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Autry AE, Adachi M, Nosyreva E, Na ES, Los MF, Cheng PF, Kavalali ET, Monteggia LM.
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9111, USA.
Nature. 2011 Jun 15;475(7354):91-5. doi: 10.1038/nature10130.
Abstract
Clinical studies consistently demonstrate that a single sub-psychomimetic dose of ketamine, an ionotropic glutamatergic NMDAR (N-methyl-D-aspartate receptor) antagonist, produces fast-acting antidepressant responses in patients suffering from major depressive disorder, although the underlying mechanism is unclear. Depressed patients report the alleviation of major depressive disorder symptoms within two hours of a single, low-dose intravenous infusion of ketamine, with effects lasting up to two weeks, unlike traditional antidepressants (serotonin re-uptake inhibitors), which take weeks to reach efficacy. This delay is a major drawback to current therapies for major depressive disorder and faster-acting antidepressants are needed, particularly for suicide-risk patients. The ability of ketamine to produce rapidly acting, long-lasting antidepressant responses in depressed patients provides a unique opportunity to investigate underlying cellular mechanisms. Here we show that ketamine and other NMDAR antagonists produce fast-acting behavioural antidepressant-like effects in mouse models, and that these effects depend on the rapid synthesis of brain-derived neurotrophic factor. We find that the ketamine-mediated blockade of NMDAR at rest deactivates eukaryotic elongation factor 2 (eEF2) kinase (also called CaMKIII), resulting in reduced eEF2 phosphorylation and de-suppression of translation of brain-derived neurotrophic factor. Furthermore, we find that inhibitors of eEF2 kinase induce fast-acting behavioural antidepressant-like effects. Our findings indicate that the regulation of protein synthesis by spontaneous neurotransmission may serve as a viable therapeutic target for the development of fast-acting antidepressants.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172695/pdf/nihms313008.pdf
Abordajes innovadores para el manejo de la depresión refractaria. La historia de la ketamina
Innovative approaches to treatment - refractory depression: The ketamine story.
Rao TS, Andrade C.
Indian J Psychiatry. 2010 Apr;52(2):97-9. doi: 10.4103/0019-5545.64573.
Antidepressant drugs have traditionally addressed the monoamine triumvirate: serotonin, noradrenaline, and dopamine. There have been predominantly two mechanisms recruited in drug action - inhibition of monoamine reuptake and inhibition of intravesicular monoamine catabolism. Tianeptine, which increases the synaptic reuptake of serotonin, and mirtazapine, which blocks alpha-2 adrenergic autoreceptors and heteroreceptors, are examples of the very few drugs which have other mechanisms of action. Yet, even these two antidepressants target the traditional neurotransmitters in psychiatry
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927899/
Ketamina para el tratamiento de la depresión
Ketamine for the treatment of depression
Robert H. Howland
Journal of Psychosocial Nursing * Vol. 51, No. 1, 2013
http://www.healio.com/~/media/Journals/JPN/2013/1_January/10_3928_02793695
_20121219_01/10_3928_02793695_20121219_01.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Oral ketamine for the rapid treatment of depression and anxiety in patients receiving hospice care.
Irwin SA, Iglewicz A.
Institute for Palliative Medicine at San Diego Hospice, Palliative Care Psychiatry, San Diego, California 92103, USA. sirwin@sdhospice.org
J Palliat Med. 2010 Jul;13(7):903-8. doi: 10.1089/jpm.2010.9808.
Abstract
Depression is prevalent and undertreated in patients receiving hospice care. Standard antidepressants do not work rapidly or often enough to benefit most of these patients. Here, two cases are reported in which a single oral dose of ketamine provided rapid and moderately sustained symptom relief for both depression and anxiety. In addition, no adverse effects were noted. Further investigation with randomized, controlled clinical trials is necessary to firmly establish the effectiveness of oral ketamine for the treatment of depression and anxiety in patients receiving hospice care. Ketamine may be a promising safe, effective, and cost-effective rapid treatment for depression and anxiety in this population.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120058/pdf/jpm.2010.9808.pdf
El bloqueo del receptor NMDA en reposo desencadena respuestas antidepresivas conductuales rápidas
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Autry AE, Adachi M, Nosyreva E, Na ES, Los MF, Cheng PF, Kavalali ET, Monteggia LM.
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9111, USA.
Nature. 2011 Jun 15;475(7354):91-5. doi: 10.1038/nature10130.
Abstract
Clinical studies consistently demonstrate that a single sub-psychomimetic dose of ketamine, an ionotropic glutamatergic NMDAR (N-methyl-D-aspartate receptor) antagonist, produces fast-acting antidepressant responses in patients suffering from major depressive disorder, although the underlying mechanism is unclear. Depressed patients report the alleviation of major depressive disorder symptoms within two hours of a single, low-dose intravenous infusion of ketamine, with effects lasting up to two weeks, unlike traditional antidepressants (serotonin re-uptake inhibitors), which take weeks to reach efficacy. This delay is a major drawback to current therapies for major depressive disorder and faster-acting antidepressants are needed, particularly for suicide-risk patients. The ability of ketamine to produce rapidly acting, long-lasting antidepressant responses in depressed patients provides a unique opportunity to investigate underlying cellular mechanisms. Here we show that ketamine and other NMDAR antagonists produce fast-acting behavioural antidepressant-like effects in mouse models, and that these effects depend on the rapid synthesis of brain-derived neurotrophic factor. We find that the ketamine-mediated blockade of NMDAR at rest deactivates eukaryotic elongation factor 2 (eEF2) kinase (also called CaMKIII), resulting in reduced eEF2 phosphorylation and de-suppression of translation of brain-derived neurotrophic factor. Furthermore, we find that inhibitors of eEF2 kinase induce fast-acting behavioural antidepressant-like effects. Our findings indicate that the regulation of protein synthesis by spontaneous neurotransmission may serve as a viable therapeutic target for the development of fast-acting antidepressants.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172695/pdf/nihms313008.pdf
Abordajes innovadores para el manejo de la depresión refractaria. La historia de la ketamina
Innovative approaches to treatment - refractory depression: The ketamine story.
Rao TS, Andrade C.
Indian J Psychiatry. 2010 Apr;52(2):97-9. doi: 10.4103/0019-5545.64573.
Antidepressant drugs have traditionally addressed the monoamine triumvirate: serotonin, noradrenaline, and dopamine. There have been predominantly two mechanisms recruited in drug action - inhibition of monoamine reuptake and inhibition of intravesicular monoamine catabolism. Tianeptine, which increases the synaptic reuptake of serotonin, and mirtazapine, which blocks alpha-2 adrenergic autoreceptors and heteroreceptors, are examples of the very few drugs which have other mechanisms of action. Yet, even these two antidepressants target the traditional neurotransmitters in psychiatry
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927899/
Ketamina para el tratamiento de la depresión
Ketamine for the treatment of depression
Robert H. Howland
Journal of Psychosocial Nursing * Vol. 51, No. 1, 2013
http://www.healio.com/~/media/Journals/JPN/2013/1_January/10_3928_02793695
_20121219_01/10_3928_02793695_20121219_01.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Excitación retardada
Excitación retardada
Delayed arousal.
Anastasian ZH, Ornstein E, Heyer EJ.
Division of Neurosurgical Anesthesiology, Department of Anesthesiology, Columbia University, New York, NY 10032, USA. zh2114@columbia.edu
Anesthesiol Clin. 2009 Sep;27(3):429-50. doi: 10.1016/j.anclin.2009.07.007.
Abstract
Elderly patients have medical and psychological problems affecting all major organ systems. These problems may alter the pharmacokinetics and/or pharmacodynamics of medications, or expose previous neurologic deficits simply as a result of sedation. Delayed arousal, therefore, may arise from structural problems that are pre-existent or new, or metabolic or functional disorders such as convulsive or nonconvulsive seizures. Determining the cause of delayed arousal may require clinical, chemical, and structural tests. Structural problems that impair consciousness arise from a small number of focal lesions to specific areas of the central nervous system, or from pathology affecting the cerebrum. In general, focal or multifocal lesions can be identified by computerized tomography, or diffusion-weighted imaging. An algorithm is presented that outlines a workup for an elderly patient with delayed arousal.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036001/pdf/nihms-158134.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Levobupivacaína/Levobupivacaine
Levobupivacaína para el tratamiento de dolor postoperatorio en la circuncisión: bloqueo caudal o dorsal del pene
Levobupivacaine for postoperative pain management in circumcision: caudal blocks or dorsal penile nerve block.
Kazak Bengisun Z, Ekmekci P, Haliloğlu AH.
Department of Anesthesiology and Reanimation, Ufuk University, Faculty of Medicine, Ankara, Turkey. kazakzuleyha@yahoo.com
Agri. 2012 Oct;24(4):180-6. doi: 10.5505/agri.2012.21931.
Abstract
OBJECTIVES: In this study, we evaluated the analgesic efficacy and adverse effect profile of levobupivacaine in caudal and DPNB in postcircumcision pediatric patients. METHODS: Sixty boys between 2-10 years of age undergoing circumcision were enrolled. The patients were divided into two groups: Group C (n=30) and Group P (n=30) were applied caudal block or dorsal penile nerve block (DPNB), respectively. Blocks were performed before surgery as a supplement to general anesthesia with 1 mL kg(-1) 0.25% levobupivacaine. Postoperative pain and sedation scores were assessed on the 10th and 30th minutes, and hours 1-6. The number of pain free patients in the first 6 hours, the duration of analgesia, time to first analgesic administration, walking, micturition, and total paracetamol demands, and length of stay were recorded. RESULTS: Demographic data were similar between groups. The number of children who spent the first 6 hours pain-free was larger in Group C than Group P (p=0.0001). The time to first analgesic (p=0.000033) and walking (p=0.004) were longer in Group C. There were 14 patients with motor block in Group C (p=0.00007). In view of AUC, FPRS, OPS and MPOPS were significantly better in Group C on the first postoperative 6 hours. CONCLUSION: Caudal block done using levobupivacaine for postoperative pain management in circumcision is more successful than penile block, however there is a significant delay in time to first walking and as might be expected there is an increased risk of motor block.
http://www.journalagent.com/pubmed/linkout.asp?ISSN=1300-0012&PMID=23364781
Características clínicas de levobupivacaína espinal: hiperbárica comparada con solución isobárica
Clinical characteristics of spinal levobupivacaine: hyperbaric compared with isobaric solution.
Sanansilp V, Trivate T, Chompubai P, Visalyaputra S, Suksopee P, Permpolprasert L, von Bormann B.
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
ScientificWorldJournal. 2012;2012:169076. doi: 10.1100/2012/169076. Epub 2012 Apr 24.
Abstract
We performed a prospective, double-blinded study in 20 patients undergoing gynecologic surgery with lower abdominal incision, to investigate characteristics of intrathecal hyperbaric levobupivacaine compared with isobaric levobupivacaine. We randomly assigned them to receive 3 ml of either isobaric or hyperbaric 0.42% levobupivacaine intrathecally We found that hyperbaric levobupivacaine, compared with isobaric levobupivacaine, spread faster to T10 level (2.8 ± 1.1 versus 6.6 ± 4.7 minutes, P = 0.039), reached higher sensory block levels at 5 and 15 minutes after injection (T8 versus L1, P = 0.011, and T4 versus T7, P = 0.027, resp.), and had a higher peak level (T4 versus T8, P = 0.040). Isobaric levobupivacaine caused a wider range of peak levels (L1 to C8) compared with hyperbaric form (T7 to T2). The level of T4 or higher reached 90% in the hyperbaric group compared with 20% in the isobaric group (P = 0.005). Our results suggest that hyperbaric levobupivacaine was more predictable for sensory block level and more effective for surgical procedures with lower abdominal approach. Hyperbaric levobupivacaine seems to be suitable, but the optimal dosage needs further investigation.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349113/pdf/TSWJ2012-169076.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Levobupivacaine for postoperative pain management in circumcision: caudal blocks or dorsal penile nerve block.
Kazak Bengisun Z, Ekmekci P, Haliloğlu AH.
Department of Anesthesiology and Reanimation, Ufuk University, Faculty of Medicine, Ankara, Turkey. kazakzuleyha@yahoo.com
Agri. 2012 Oct;24(4):180-6. doi: 10.5505/agri.2012.21931.
Abstract
OBJECTIVES: In this study, we evaluated the analgesic efficacy and adverse effect profile of levobupivacaine in caudal and DPNB in postcircumcision pediatric patients. METHODS: Sixty boys between 2-10 years of age undergoing circumcision were enrolled. The patients were divided into two groups: Group C (n=30) and Group P (n=30) were applied caudal block or dorsal penile nerve block (DPNB), respectively. Blocks were performed before surgery as a supplement to general anesthesia with 1 mL kg(-1) 0.25% levobupivacaine. Postoperative pain and sedation scores were assessed on the 10th and 30th minutes, and hours 1-6. The number of pain free patients in the first 6 hours, the duration of analgesia, time to first analgesic administration, walking, micturition, and total paracetamol demands, and length of stay were recorded. RESULTS: Demographic data were similar between groups. The number of children who spent the first 6 hours pain-free was larger in Group C than Group P (p=0.0001). The time to first analgesic (p=0.000033) and walking (p=0.004) were longer in Group C. There were 14 patients with motor block in Group C (p=0.00007). In view of AUC, FPRS, OPS and MPOPS were significantly better in Group C on the first postoperative 6 hours. CONCLUSION: Caudal block done using levobupivacaine for postoperative pain management in circumcision is more successful than penile block, however there is a significant delay in time to first walking and as might be expected there is an increased risk of motor block.
http://www.journalagent.com/pubmed/linkout.asp?ISSN=1300-0012&PMID=23364781
Características clínicas de levobupivacaína espinal: hiperbárica comparada con solución isobárica
Clinical characteristics of spinal levobupivacaine: hyperbaric compared with isobaric solution.
Sanansilp V, Trivate T, Chompubai P, Visalyaputra S, Suksopee P, Permpolprasert L, von Bormann B.
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
ScientificWorldJournal. 2012;2012:169076. doi: 10.1100/2012/169076. Epub 2012 Apr 24.
Abstract
We performed a prospective, double-blinded study in 20 patients undergoing gynecologic surgery with lower abdominal incision, to investigate characteristics of intrathecal hyperbaric levobupivacaine compared with isobaric levobupivacaine. We randomly assigned them to receive 3 ml of either isobaric or hyperbaric 0.42% levobupivacaine intrathecally We found that hyperbaric levobupivacaine, compared with isobaric levobupivacaine, spread faster to T10 level (2.8 ± 1.1 versus 6.6 ± 4.7 minutes, P = 0.039), reached higher sensory block levels at 5 and 15 minutes after injection (T8 versus L1, P = 0.011, and T4 versus T7, P = 0.027, resp.), and had a higher peak level (T4 versus T8, P = 0.040). Isobaric levobupivacaine caused a wider range of peak levels (L1 to C8) compared with hyperbaric form (T7 to T2). The level of T4 or higher reached 90% in the hyperbaric group compared with 20% in the isobaric group (P = 0.005). Our results suggest that hyperbaric levobupivacaine was more predictable for sensory block level and more effective for surgical procedures with lower abdominal approach. Hyperbaric levobupivacaine seems to be suitable, but the optimal dosage needs further investigation.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349113/pdf/TSWJ2012-169076.pdf
Atentamente
Anestesiología y Medicina del Dolor
www.anestesia-dolor.org
Bibliotecas. Alerta
La Biblioteca Nacional lleva a cabo su octava recolección de la web ...
ABC.es
La Biblioteca Nacional de España ha cumplido trescientos años, pero día a día sigue mirando al futuro o a lo que ya es presente digital. En este sentido, desde finales de este mes y a lo largo del mes de junio, la institución va a llevar a cabo la ...
Ver todos los artículos sobre este tema »
El biógrafo de los Beatles dona canciones de Lennon a la Biblioteca ...
EFE
Londres, 23 may (EFE).- El aclamado biógrafo de los Beatles Hunter Davies ha donado cartas y canciones manuscritas por John Lennon a la Biblioteca Británica, que las expondrá en la galería de los Tesoros junto a obras de Beethoven y Shakespeare.
Ver todos los artículos sobre este tema »
La biblioteca de Lalín, la gran olvidada
Faro de Vigo
Hace poco más de dos años, una interesante iniciativa surgía en una conocida red social con el principal objetivo de solicitar cambios en la estructura y organización de la biblioteca municipal de Lalín y contar así de una vez por todas con una ...
Ver todos los artículos sobre este tema »
Las termitas cierran la biblioteca en exámenes
Faro de Vigo
La Biblioteca Pública Central permanece cerrada esta semana "por motivos de seguridad". El tratamiento contra las terminas que se está aplicando al edificio de Joaquín Yáñez ha dejado sin sala de estudio a docenas de estudiantes que por estas fechas ...
Ver todos los artículos sobre este tema »
La Biblioteca de las Palomas se queda sin luz... y sin explicaciones
Granada Hoy
Cuando el pasado mes de diciembre los vecinos cantaron victoria porque pensaban que el cambio de titularidad del inmueble de la Biblioteca de las Palomas del Ayuntamiento de Granada a la Junta de Andalucía había supuesto la recuperación del ...
Ver todos los artículos sobre este tema »
El complejo El Águila celebra su X aniversario con la exposición ...
Lainformacion.com
Madrid, 22 may (EFE).- El Complejo El Aguila, sede del Archivo y de la Biblioteca regional Joaquín Leguina, acoge hasta el próximo 28 de julio la exposición "Descubre Madrid", una selección de 132 manuscritos, publicaciones, dibujos originales, mapas o ...
Ver todos los artículos sobre este tema »
La UCAB inauguró edificio para crear e investigar
El Nacional.com
En la Universidad Católica Andrés Bello hay razones para celebrar. Ayer en la mañana fue inaugurado el centro cultural Padre Carlos Guillermo Plaza: una edificación de 14.000 metros cuadrados y 4 niveles que alberga la sede de una nueva biblioteca, ...
Ver todos los artículos sobre este tema »
Las Bibliotecas generan actividades para cumplir con su fin y ...
Diario El Argentino
Las actividades culturales y sociales que generan las propias Bibliotecas populares dejan ingresos que ayudan a solventar el día a día, pero esto no es suficiente. Como se anunció, en el marco del Café de las Artes de la Biblioteca Sarmiento, se ...
Ver todos los artículos sobre este tema »
La primera biblioteca sin libros del mundo
BBC Mundo
Una biblioteca sin libros suena a chiste, excepto para los que pronto inaugurarán en Texas, Estados Unidos, la que se considera es la primera biblioteca pública sin libros de papel del mundo. La llamada BiblioTech es un ambicioso proyecto que se ...
Ver todos los artículos sobre este tema »
Gian Marco en impecable presentación en tributo a Carole King
Radio Programas del Perú
Créditos: Armando Gallardo. Biblioteca del Congreso de Estados Unidos le entregó la distinción 2013 Library of Congress Gershwin Priza for Popular Song en una ceremonia con más de mil invitados.
Ver todos los artículos sobre este tema »
Biblioteca Rne | Facebook
Biblioteca Rne is on Facebook. Join Facebook to connect with Biblioteca Rne and others you may know. Facebook gives people the power to share and makes ...
www.facebook.com/biblioteca.sollorne?hc_location=stream
Revision of UKA: Is There a Difference Compared to Primary TKA and Revision TKA?
Revision of UKA: Is There a Difference Compared to Primary TKA and Revision TKA?Faculty: Jean-Noel Argensonicjr.net/media/video.39…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
jueves, 23 de mayo de 2013
El condroitín sulfato ha demostrado actuar sobre las tres estructuras de la articulación..…
El condroitín sulfato ha demostrado actuar sobre las tres estructuras de la articulación..…exicanodeortopediaytrauma.blogspot.mx/2013/05/el-con… twitter.com/bibliomanaztec…
— Victor Ravens (@bibliomanazteca) 24 de mayo de 2013
Suscribirse a:
Entradas (Atom)