| Uso de dexmedetomidina para control del dolor |
Use of dexmedetomidine for pain control
Irina Grosu and Patricia Lavand'homme
F1000 Medicine Reports 2010, 2:90 (doi:10.3410/M2-90)
ABSTRACT
For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the intensive care unit. However, DMET has recently been investigated for its analgesic effects and has the potential to become an alternative to clonidine
http://f1000.com/reports/m/2/90/pdf
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