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miércoles, 26 de enero de 2011

Uso de catéteres epidurales y bloqueos de nervios periféricos al final de la vida en niños y adultos jóvenes con cáncer: la colaboración entre el servicio de dolor y de cuidados paliativos


Uso de catéteres epidurales y bloqueos de nervios periféricos al final de la vida en niños y adultos jóvenes con cáncer: la colaboración entre el servicio de dolor y de cuidados paliativos
Use of epidural and peripheral nerve blocks at the end of life in children and young adults with cancer: the collaboration between a pain service and a palliative care service
DORALINA L. ANGHELESCU MD, LANE G. FAUGHNAN BS, JUSTIN N. BAKER MD, J IE YANG PhD AND JAVIER R.KANE MD
Division of Anesthesiology, Division of Palliative and End-of-Life Care and Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA
Pediatric Anesthesia 2010 20: 1070-1077 doi:10.1111/j.1460-9592.2010.03449.x 

Summary
Background: Clinicians may avoid continuous pain blocks in pediatric  cancer patients at the end of life for fear of complications or of interfering with the desired location of death. Objectives: To examine the impact of epidural or peripheral nerve catheters on pain control in children and young adults with cancer within the last 3 months of life. Methods: We retrospectively reviewed the medical records to assess pain scores, systemic opioid requirements, and impact on death at the preferred location. Results: Ten patients (4.4-21.3 years of age), nine with solid tumors, one with lymphoma, had 14 devices (11 epidural, 3 peripheral nerve catheters) for a range of 3-81 days. Twelve of 13 catheters provided improvement by at least one of three criteria: improved mean pain scores at 24 h (8 of 13) and decreased opioid requirement at 24 h in nine cases and at day 5 in nine cases. Eight patients died in their preferred setting. Six patients had catheters (five epidural, one peripheral) until death, including two who died at home. In some cases, typical contraindications for indwelling catheters (spinal metastasis, vertebral fracture, thrombocytopenia, fever) were superseded by palliative care needs. We found no bleeding, infectious, or neurological complications. Conclusions: Our findings suggest that continuous catheter-delivered pain blockade at the end of life contributes to analgesia, moderates opioid requirements, and usually does not preclude death at the preferred location.
Keywords: pain; cancer; end of life; epidural; peripheral nerve block.

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Atentamente
Dr. Enrique Hernández-Cortes
Anestesiología y Medicina del Dolor

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