domingo, 11 de marzo de 2012

Rosalind Franklin, The Dark Lady of DNA


ScienceSunday  -  09:21  -  Público
The Dark Lady of DNA

In keeping with the Women in Science theme, +Siromi Samarasingheshares the interesting story of Rosalind Fanklin.
Foto del perfil de Siromi SamarasingheSiromi Samarasinghe compartió inicialmente esta publicación:
Rosalind Franklin, The Dark Lady of DNA
#sciencesunday curated by +Allison Sekuler and +Robby Bowles

The award winning biographer Brenda Maddox records the biography of Rosalind Franklin in her book titled ‘Rosalind Franklin, The DarkLady of DNA’ where she portrays Franklin as a determined perfectionist, single minded and forthright, whose work had not been given due recognition for the discoveryof the double helix structure of DNA.

Franklin’s X-ray diffraction photographs of DNA and her precise measurements of the unitcell (the smallest repeating unit) of DNA showed unmistakable evidence of a helical structure, clearly demonstrating that DNA was a doublehelix. This finding contradicted the view held at the time by Watson and Crick, regarding the structure of the DNA molecule.

In 1962 Watson, Crick and Wilkins were awarded the Nobel Prize for the discovery of DNA leavingout Franklin from the greatest scientific discovery of the 20th century. Rosalind Franklin died of ovarian cancer in 1958, (probably her carelessness when handling the x-ray crystallography equipment was a contributory factor). She died not knowing that her work had been crucial forthe discovery of the double helix structure of DNA.

The Nobel Prize is awardedonly to those who are still alive, and it was four years after her death that Watson, Crick, and Wilkins received the award. Though Franklin was not eligible,many share the thought that she deserved explicit mention at the time of receiving the award by the other three scientist.

At a time when the achievement of women scientists were undermined and overlooked Rosalind Franklin carried on regardless, and accomplished much in her field. She was a scientist of the highest calibre,one who devoted her life to science.

The crucial x-ray diffraction image "Photo 51" is shown here.
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